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Foods
Special Issues
Fusarium Species and Their Mycotoxins in Cereal Food
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Fusarium Species and Their Mycotoxins in Cereal Food

A special issue of Foods (ISSN 2304-8158). This special issue belongs to the section "Food Toxicology".

Deadline for manuscript submissions: 30 April 2025 | Viewed by 209

Special Issue Editors

Dr. Na Liu

E-Mail Website
Guest Editor
SIBS-UGENT-SJTU Joint Laboratory of Mycotoxin Research, CAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai 200030, China
Interests: mycotoxin; mass spectrometry detection technology; rapid detection; contamination control; risk assessment; food safety
Dr. Song Yu

E-Mail Website
Guest Editor
Division of Chemical Toxicity and Safety Assessment, Shanghai Center for Disease Control and Prevention, Shanghai 200336, China
Interests: mycotoxin; mass spectrometry detection technology; contamination control; toxicity intervention; food quality and safety assessment
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Fusarium is one of the major disease-causing organisms of crops. Moreover, they produce mycotoxins, which are toxic secondary metabolites. Mycotoxins have been found to be prevalent in cereals and organisms. They are considered a threat to agriculture, food and feed chains, and human and animal health. Therefore, understanding the mechanism of mycotoxin synthesis, contamination status, health hazards, and risk assessment has become a very important issue.

The aim of this Special Issue is to provide an overview of the latest developments and applications in the above-mentioned research areas. It showcases the latest research advances and/or the current status of innovative approaches, methods, and technologies, focusing on the contamination and hazard control of Fusarium and mycotoxins, as well as changes in the occurrence and distribution of mycotoxins as a result of changing environmental conditions.

This Special Issue invites original research and review articles that address advances and trends in a variety of aspects of mycotoxins, including source and synthesis, detection and distribution, metabolism and transformation, mechanisms of action and effects, evaluation and management, and control and detoxification.

Dr. Na Liu
Dr. Song Yu
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Foods is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Fusarium species
  • mycotoxins
  • synthetic regulation
  • fast detection method
  • contamination
  • internal exposure risk assessment
  • toxicity mechanism
  • biological control
  • new challenges and trends

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Published Papers (1 paper)

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Research

12 pages, 1154 KiB  
Article
Resveratrol Alleviates Fumonisin B1-Induced Cytotoxicity in Sertoli Cells
by Song Yu, Lianpeng Zou, Jiawei Zhao and Yiping Zhu
Foods 2024, 13(23), 3810; https://doi.org/10.3390/foods13233810 - 26 Nov 2024
Abstract
Fumonisin B1 is a common food contaminant that has been found to adversely affect the reproductive system, especially Sertoli cells. However, the potential mitigation of FB1-induced cytotoxicity in Sertoli cells has not been fully elaborated. Resveratrol is a natural substance with anti-inflammatory, antioxidant, [...] Read more.
Fumonisin B1 is a common food contaminant that has been found to adversely affect the reproductive system, especially Sertoli cells. However, the potential mitigation of FB1-induced cytotoxicity in Sertoli cells has not been fully elaborated. Resveratrol is a natural substance with anti-inflammatory, antioxidant, and anti-tumor properties. Herein, the protective effects of resveratrol against FB1-induced cytotoxicity in Sertoli cells were examined in this work. The mouse Sertoli cell line (TM4) was used as a research model. These results indicated that FB1 (40 μM and 80 μM) significantly reduces cell viability, disrupts the cell barrier, and induces an inflammatory response in TM4 cells. To our surprise, resveratrol (15 μM) showed an ability to reverse adverse effects induced by FB1 (40 μM). Furthermore, resveratrol could alleviate the FB1-induced apoptosis, decrease ROS level, and promote the antioxidant enzymes (CAT and SOD2) expression in FB1-treated TM4 cells. The addition of resveratrol could mitigate FB1-induced promoted phosphorylation of JNK and upregulation of c-jun expression. Interestingly, resveratrol was also able to mitigate the cytotoxicity of FB2 (40 μM), FB3 (40 μM), and an FB1-FB2-FB3 (40 μM-40 μM-40 μM) combination group on TM4 cells. In summary, this research displayed that resveratrol may alleviate fumonisin B1-induced cytotoxicity in Sertoli cells via inhibiting oxidative stress-mediated JNK/c-jun signaling pathway-induced apoptosis. This study provides new insights into the prevention and treatment of FB1-induced testicular toxicity and highlights the potential application value of resveratrol. Full article
(This article belongs to the Special Issue Fusarium Species and Their Mycotoxins in Cereal Food)
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