Epigenetic Modifications in Cancer: Mechanisms, Diagnostics and Therapeutic Implications
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Genetics and Genomics".
Deadline for manuscript submissions: 20 December 2024 | Viewed by 1088
Special Issue Editor
Interests: epigenetics; DNA methylation; histone modifications
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
This Special Issue will delve into the intricate world of epigenetic modifications and their profound impacts on cancer development, progression, and treatment. Epigenetics, encompassing DNA methylation, histone modification, and non-coding RNA regulation, plays a pivotal role in the regulation of gene expression without altering the genetic code itself. These modifications can lead to oncogene activation or tumor suppressor gene silencing, contributing to the onset and progression of various cancers.
The Special Issue will bring together cutting-edge research and comprehensive reviews highlighting the latest advancements in our understanding of the epigenetic mechanisms driving cancer. It will cover the development of novel diagnostic tools that leverage epigenetic markers for early cancer detection and prognostication. Additionally, it will explore innovative therapeutic strategies that target epigenetic alterations, offering new hope for precision medicine in oncology.
By providing a platform for interdisciplinary collaboration, this Special Issue will bridge the gap between basic research and clinical application, fostering the translation of epigenetic discoveries into tangible benefits for cancer patients. Thus, for this Special Issue of IJMS, we invite contributions from researchers and clinicians dedicated to advancing knowledge and improving outcomes in the fight against cancer through epigenetics.
Dr. Yonghwan Shin
Guest Editor
Manuscript Submission Information
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Keywords
- cancer
- epigenetic
- next-generation sequencing
- epigenome mapping
- DNA methylation
- histone modifications
- non-coding RNA involvement
- chromatin remodeling
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