The Carcinogenetic Potential of Human Papilloma Virus: From Experimental Studies to Targeted Therapy
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".
Deadline for manuscript submissions: 20 December 2024 | Viewed by 356
Special Issue Editor
Interests: oncopathology; gastric cancer; colorectal cancer; hepatocellular carcinoma; epithelial–mesenchymal transition; targeted therapy of cancer; histopathology; molecular pathology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The scope of this special issue is to collect papers referring to the carcinogenic role of Human Papilloma virus (HPV). It is known to be involved in genesis of cervical cancer, anal canal but also head and neck malignancies but the exact role in pathogenesis and evolution of these carcinomas is far to be understood. Moreover, although p16 is used as the surrogate marker in immunohistochemistry, as a tool for identification of HPV mutations, the PCR determinations do not confirm in any case the association between gene status and protein expression. Based on this fact, a deeply examination of HPV interactions and carcinogenic potential deserves attention. The prognostic and predictive role of HPV in oncology patients is also worthy to be explored. Any review or original-type article is welcome, including experimental, basic research or clinical data. If some papers are mainly based on in silico analysis or examination of public gene databases, they should include an external validation on own cohort. We hope to collect interesting papers that help researchers to have a better understanding of HPV and medical doctors to have an whole picture of HPV, from carcinogenesis to drug resistance.
Prof. Dr. Simona Gurzu
Guest Editor
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Keywords
- human papilloma virus
- head and neck cancer
- squamous cell carcinoma
- oropharyngeal cancer
- non-oropharyngeal malignancies
- anal canal
- uterine cervix
- tumor tissue
- PCR
- NGS
- oncology
- pathology
- carcinogenesis
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