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The Food Processing Industry’s 200th Anniversary: Bioactive Compounds, Antioxidants, and Potential Health Benefits (2nd Edition)

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Bioactives and Nutraceuticals".

Deadline for manuscript submissions: 31 March 2025 | Viewed by 983

Special Issue Editor

Special Issue Information

Dear Colleagues,

"The industrial revolution" is a shorthand term for a historical era that began in Great Britain in the 18th century and was characterized by an apparent acceleration of progress. Over the years, the food industry has changed and adapted to meet changing consumer demands and behaviors. The supply, consumption, and delivery of food products around the world are part of a complex system that defines this industry. Food processes can bestow the potential health benefits of bioactive compounds in processed food products. People with allergies, diabetes, and other health issues who cannot consume certain common food items also benefit from modern food processing. Additional nutrients, such as vitamins and antioxidants, can be added to foods during processing. Food processing offers a number of advantages, such as extending the shelf life of food and improving the usability of products; however, highly processed meals can have disadvantages. According to the World Health Organization, a diet high in fat, added sugar, and salt, such as one that includes many highly processed foods, can increase the risk of cancer, type 2 diabetes, and heart disease. The key is to strike a balance between the advantages and disadvantages of food processing. This can be achieved by consuming a mix of whole, minimally processed foods and those that have undergone some processing to improve their safety, taste, and nutritional value. It is also important to be mindful of the ingredients used in processed foods and to choose options that are made with natural ingredients.

Since it is necessary to develop approaches that provide improved food products for human health and wellbeing, while minimizing their environmental impact, such that the circular economy becomes a reality in food (and industrial) processing, this Special Issue on "The Food Processing Industry’s 200th Anniversary: Bioactive Compounds, Antioxidants, and Potential Health Benefits (2nd Edition)" will (I) explore the maintenance or enhancement of the concentration of bioactive compounds that can be used as functions in foods during their processing and (II) examine the mechanisms by which the desired effect is achieved. Original research articles and reviews on the topic are welcome.

Dr. Vassilis Athanasiadis
Guest Editor

Manuscript Submission Information

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Keywords

  • antioxidants
  • bioactive compounds
  • food processing
  • functional foods
  • green processes
  • health potentials
  • molecular mechanisms
  • polyphenols
  • shelf life
  • vitamins

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Published Papers (1 paper)

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Research

29 pages, 5462 KiB  
Article
Phytochemical Profile and In Vitro Cytotoxic, Genotoxic, and Antigenotoxic Evaluation of Cistus monspeliensis L. Leaf Extract
by Ghanya Al-Naqeb, Gianluca Zorzi, Amanda Oldani, Alberto Azzalin, Linda Avesani, Flavia Guzzo, Alessia Pascale, Rachele De Giuseppe and Hellas Cena
Int. J. Mol. Sci. 2024, 25(24), 13707; https://doi.org/10.3390/ijms252413707 - 22 Dec 2024
Viewed by 594
Abstract
Cistus monspeliensis L. (C. monspeliensis) is used in Italian folk medicine. This study was performed to determine genotoxic and antigenotoxic effects of C. monspeliensis leaf extract against mitomycin C (MMC) using an in vitro cytokinesis-block micronucleus assay (CBMN) in the Chinese [...] Read more.
Cistus monspeliensis L. (C. monspeliensis) is used in Italian folk medicine. This study was performed to determine genotoxic and antigenotoxic effects of C. monspeliensis leaf extract against mitomycin C (MMC) using an in vitro cytokinesis-block micronucleus assay (CBMN) in the Chinese Hamster Ovarian K1 (CHO-K1) cell line. The phytochemical composition of C. monspeliensis extract was evaluated using an untargeted metabolomic approach by employing UPLC-PDA-ESI/MS. The automated in vitro CBMN assay was carried out using image analysis systems with a widefield fluorescence microscope and the ImageStreamX imaging flow cytometer. The phytochemical profile of C. monspeliensis extract showed, as the most abundant metabolites, punicalagin, myricetin, gallocathechin, and a labdane-type diterpene. C. monspeliensis, at the tested concentrations of 50, 100, and 200 μg/mL, did not induce significant micronuclei frequency, thus indicating the absence of a genotoxic potential. When testing the C. monspeliensis extract for antigenotoxicity in the presence of MMC, we observed a hormetic concentration-dependent effect, where low concentrations resulted in a significant protective effect against MMC-induced micronuclei frequency, and higher concentrations resulted in no effect. In conclusion, our findings demonstrate that C. monspeliensis extract is not genotoxic and, at low concentration, exhibits an antigenotoxic effect. In relation to this final point, C. monspeliensis may act as a potential chemo-preventive against genotoxic agents. Full article
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