Journal of Clinical Medicine

Research

16 pages, 4171 KiB

Open AccessArticle

Evaluation of Peri-Implantitis Bone Defect Healing: Comparing the Efficacy of Small-Particle Dentin and Bio-Oss in Bone Density Attenuation

by Michał Łobacz, Katarzyna Wieczorek, Paulina Mertowska, Sebastian Mertowski, Marek Kos, Ewelina Grywalska, Grzegorz Hajduk and Mansur Rahnama-Hezavah

J. Clin. Med. 2024, 13(16), 4638; https://doi.org/10.3390/jcm13164638 - 8 Aug 2024

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Abstract

Introduction: Peri-implantitis is a serious complication in dental implantology that, if left untreated, may lead to implant loss and systemic diseases. Effective regeneration of bone defects resulting from peri-implantitis is crucial to maintaining the functionality of dental implants. Purpose of the Study: The [...] Read more.

Introduction: Peri-implantitis is a serious complication in dental implantology that, if left untreated, may lead to implant loss and systemic diseases. Effective regeneration of bone defects resulting from peri-implantitis is crucial to maintaining the functionality of dental implants. Purpose of the Study: The study aimed to compare the effectiveness of fine-particle dentin and Bio-Oss in the reconstruction of bone defects caused by peri-implantitis. Materials and Methods: The study included a comprehensive radiological assessment of changes in bone density over time. Bone density was assessed using Hounsfield Units (HUs) as a measure of bone attenuation, with radiological assessments performed at 8- and 12-week intervals during the healing process. The study included participants ranging in age from 30 to 65 years. Fifty-seven patients were divided into three groups: 22 patients received small-particle dentin, 15 received Bio-Oss, and 20 controls without bone substitute material. Results: The fine-dentin group showed a 20% increase in bone density after 8 weeks (p < 0.05), while the Bio-Oss group showed a 15% increase after 12 weeks (p < 0.05). The control group showed minimal changes in bone density (5% after 12 weeks), which was not statistically significant. Clinical evaluations showed 95% successful integration in the fine dentin group, 85% in the Bio-Oss group, and 70% in the control group. The fine-dentin group showed a 20% increase in bone density after 8 weeks (p < 0.05), while the Bio-Oss group showed a 15% increase after 12 weeks (p < 0.05). The control group showed minimal changes in bone density (5% after 12 weeks), which was not statistically significant. Clinical evaluations showed 95% successful integration in the fine-dentin group, 85% in the Bio-Oss group, and 70% in the control group. Conclusions: Both fine-particle dentin and Bio-Oss significantly improved bone density compared to the control group. Fine-particle dentin is suitable for immediate bone regeneration due to its rapid initial regeneration, while Bio-Oss provides long-term support, ideal for maintaining implant stability over a longer period of time. The results highlight the importance of selecting appropriate bone replacement materials depending on the clinical scenario to improve patient outcomes after dental implant placement. Full article

(This article belongs to the Special Issue Current Challenges in Clinical Dentistry)

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14 pages, 5383 KiB

Open AccessArticle

Effectiveness of Clear Aligners on Sequential Maxillary Molar Distalization: Discrepancy between Treatment Goal and Outcome

by Jatuphol Mamani, Chidchanok Sessirisombat, Hitoshi Hotokezaka, Noriaki Yoshida and Irin Sirisoontorn

J. Clin. Med. 2024, 13(14), 4216; https://doi.org/10.3390/jcm13144216 - 19 Jul 2024

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Abstract

Objectives: The purpose of this preliminary study was to determine the differences between planned and actual maxillary molar movements after the completion of treatment with an initial set of clear aligners including sequential maxillary molar distalization. Methods: The data records of 14 non-growing [...] Read more.

Objectives: The purpose of this preliminary study was to determine the differences between planned and actual maxillary molar movements after the completion of treatment with an initial set of clear aligners including sequential maxillary molar distalization. Methods: The data records of 14 non-growing patients who completed orthodontic treatment with sequential maxillary molar distalization using clear aligners were retrospectively evaluated (n= 14, 4 males and 10 females, 33.61 ± 8.57 years). Data on planned tooth movements were obtained from ClinCheck software (ClinCheck Pro version 5.3). The amounts of actual tooth movements were obtained by performing superimposition of lateral cephalograms taken before and after treatment. The amounts of distal translation and tipping between planned and actual maxillary molar movements were compared with the paired Student’s t-test. Results: The statistically significant differences between planned and actual translation movements of maxillary first and second molars were shown after completing treatment with the first series of aligners (p < 0.05). The average actual amount of molar distalization on maxillary first molars was less than the planned amount by 1.32 ± 0.42 mm. Similarly, the average actual amount of molar distalization on maxillary second molars was less than the planned amount by 1.57 ± 0.45 mm. The accuracy for molar distalization, namely, the percentage of actual distal translation to planned movement, was 40.11% for maxillary first molars and 35.39% for maxillary second molars. However, the difference between the planned and actual angulation movements was not significant (p > 0.05). Conslusions: In conclusion, the amounts of actual distal translation of maxillary molars through the utilization of clear aligners were significantly lower than planned. However, there were no statistically significant differences between the degrees of actual and planned molar angulation movement. Full article

(This article belongs to the Special Issue Current Challenges in Clinical Dentistry)

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19 pages, 6978 KiB

Open AccessArticle

Relationship between Cephalometric and Ultrasonic Airway Parameters in Adults with High Risk of Obstructive Sleep Apnea

by Anutta Terawatpothong, Chidchanok Sessirisombat, Wish Banhiran, Hitoshi Hotokezaka, Noriaki Yoshida and Irin Sirisoontorn

J. Clin. Med. 2024, 13(12), 3540; https://doi.org/10.3390/jcm13123540 - 17 Jun 2024

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Abstract

Background/Objectives: Polysomnography and cephalometry have been used for studying obstructive sleep apnea (OSA) etiology. The association between craniofacial skeleton and OSA severity remains controversial. To study OSA’s etiology, cephalometry, fiberoptic pharyngoscopy, polysomnography, and sleep endoscopy have been used; however, airway obstructions cannot be [...] Read more.

Background/Objectives: Polysomnography and cephalometry have been used for studying obstructive sleep apnea (OSA) etiology. The association between craniofacial skeleton and OSA severity remains controversial. To study OSA’s etiology, cephalometry, fiberoptic pharyngoscopy, polysomnography, and sleep endoscopy have been used; however, airway obstructions cannot be located. Recent research suggested ultrasonography for OSA screening and upper airway obstruction localization. Thus, this study aims to investigate the relationship between specific craniofacial cephalometric and ultrasonic airway parameters in adults at high risk of OSA. Methods: To assess craniofacial structure, lateral cephalograms were taken from thirty-three adults over 18 with a STOP-Bang questionnaire score of three or higher and a waist-to-height ratio (WHtR) of 0.5 or higher. Airway parameters were assessed through submental ultrasound. Results: NSBA correlated with tongue base airspace width, while MP-H correlated with oropharynx, tongue base, and epiglottis airspace width. SNA, SNB, and NSBA correlated with tongue width at the oropharynx. At tongue base, ANB and MP-H correlated with tongue width. SNB and NSBA were associated with deep tissue thickness at the oropharynx, while MP-H correlated with superficial tissue thickness at velum and oropharynx. Conclusions: Cephalometric parameters (SNA, SNB, ANB, NSBA, and MP-H) were correlated with ultrasonic parameters in the velum, oropharynx, tongue base, and epiglottis. Full article

(This article belongs to the Special Issue Current Challenges in Clinical Dentistry)

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24 pages, 14811 KiB

Open AccessArticle

A Novel Therapeutic Approach of 980 nm Photobiomodulation Delivered with Flattop Beam Profile in Management of Recurrent Aphthous Stomatitis in Paediatrics and Adolescents—A Case Series with 3-Month Follow-Up

by Reem Hanna, Ioana Cristina Miron and Stefano Benedicenti

J. Clin. Med. 2024, 13(7), 2007; https://doi.org/10.3390/jcm13072007 - 29 Mar 2024

Cited by 1 | Viewed by 1444

Abstract

Background/Objectives: Recurrent aphthous stomatitis (RAS) is one of the most common oral mucosal lesions and a very debilitating lesion, especially in paediatric and adolescent patients. The current pharmacotherapy offers a pain relief but not without side effects, and therefore photobiomodulation (PBM) can [...] Read more.

Background/Objectives: Recurrent aphthous stomatitis (RAS) is one of the most common oral mucosal lesions and a very debilitating lesion, especially in paediatric and adolescent patients. The current pharmacotherapy offers a pain relief but not without side effects, and therefore photobiomodulation (PBM) can be an alternative therapy. To the authors’ best knowledge, no published study has explored the efficacy of λ 980 nm laser PBM in the management of all RAS subtypes in paediatric and adolescent patients, and therefore, this prospective observational clinical study was conducted to bridge this gap by evaluating λ 980 nm laser PBM efficacy in symptomatic RAS management in paediatric and adolescent patients. The objectives were to evaluate (1) pain intensity alleviation; (2) wound healing rate; (3) wound size closure; (4) a complete resolution; (5) evidence of recurrence; and (6) patients’ treatment satisfaction. Methods: The study’s variables were assessed at the following timepoints: T0: pre-treatment; T1: immediately after first PBM session; T2: 5 hours (h) post first PBM session (via telephone call); T3: immediately after second PBM session (three days post first PBM session); T4: three-day follow-up (after complete PBM treatments); T5: two-week follow-up; and T6: three-month follow-up. The following PBM dosimetry and treatment protocols were employed: λ 980 nm; 300 mW; 60 s; 18 J; CW; flattop beam profile of 1 cm² spot size; 18 J/cm²; and twice-a-week irradiation (72 h interval). Results: At T1, significant immediate pain intensity relief was reported. 33.33% recorded “4” and 66.67% reported “5” on the quantitative numeric pain intensity scale (NPIS), and this continued to improve significantly (83.33%) at T2. All the subjects reported “0” on the NPIS at T3, T4, T5 and T6. There was a significant reduction in the lesion surface area (>50% complete healing) at T3 compared to T0. Complete healing (100%) with no evidence of scarring and lesion recurrence observed at T4, T5 and T6. Very good patients’ satisfaction was reported at all timepoints. Conclusions: This is the first report demonstrating λ980 nm efficacy in all RAS subtype management in paediatric and adolescent patients with a 3-month follow-up, whereby its PBM dosimetry and treatment protocols were effective from scientific and practical standpoints, and hence multicentre RCTs with large data are warranted to validate its reproducibility and to enrich the knowledge of PBM application in all RAS subtypes. Full article

(This article belongs to the Special Issue Current Challenges in Clinical Dentistry)

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Graphical abstract

12 pages, 290 KiB

Open AccessArticle

Influence of Surgeon Experience on Surgical Outcome of Maxillomandibular Advancement for Obstructive Sleep Apnea

by Jean-Pierre T. F. Ho, Semih Özkan, Ning Zhou, Ruben C. Apperloo, Naichuan Su, Alfred G. Becking and Jan de Lange

J. Clin. Med. 2023, 12(10), 3504; https://doi.org/10.3390/jcm12103504 - 16 May 2023

Viewed by 1715

Abstract

The primary aim of this study was to assess the association between clinical efficacy outcomes (i.e., polysomnography (PSG) results) of maxillomandibular advancement (MMA) and surgeons’ experience. The second aim was to assess the association between the occurrence of postoperative complications of MMA and [...] Read more.

The primary aim of this study was to assess the association between clinical efficacy outcomes (i.e., polysomnography (PSG) results) of maxillomandibular advancement (MMA) and surgeons’ experience. The second aim was to assess the association between the occurrence of postoperative complications of MMA and surgeons’ experiences. Patients treated with MMA for moderate to severe obstructive sleep apnea (OSA) were enrolled in this retrospective study. The patient population was divided into two groups based on two different surgeons performing MMA. The associations between surgeons’ experience on the one hand and PSG results and postoperative complications on the other hand were investigated. A total of 75 patients were included. There was no significant difference in baseline characteristics between the two groups. The reductions in apnea-hypopnea index and oxygen desaturation index were both significantly greater in group-B than group-A (p = 0.015 and 0.002, respectively). The overall success rate after MMA was 64.0%. There was a negative correlation between surgeon experience and surgical success (odds ratio: 0.963 [0.93, 1.00], p = 0.031). No significant association was found between surgeon experience and surgical cure. Additionally, there was no significant association between surgeon experience and the occurrence of postoperative complications. Within the limitations of this study, it is concluded that surgeon experience may have little to no influence on the clinical efficacy and safety of MMA surgery in OSA patients. Full article

(This article belongs to the Special Issue Current Challenges in Clinical Dentistry)

13 pages, 1515 KiB

Open AccessArticle

Inflammatory Markers as Predictors for Prolonged Duration of Hospitalization in Maxillofacial Infections

by Horatiu Urechescu, Eleonora Gheran-Vida, Cristiana Cuzic, Oana Ancusa, Sorin Ursoniu and Marius Pricop

J. Clin. Med. 2023, 12(3), 871; https://doi.org/10.3390/jcm12030871 - 21 Jan 2023

Cited by 3 | Viewed by 1517

Abstract

Despite the progress made in diagnosing and treating maxillofacial infections, the course of infection can be unpredictable, leading to severe complications, prolonged hospitalization, and substantial financial costs to health care services. It is important to determine whether various serum inflammatory marker levels on [...] Read more.

Despite the progress made in diagnosing and treating maxillofacial infections, the course of infection can be unpredictable, leading to severe complications, prolonged hospitalization, and substantial financial costs to health care services. It is important to determine whether various serum inflammatory marker levels on admission may predict a prolonged hospital stay in these patients. To analyze the role of CRP, white blood cell count (WBC), and neutrophil-to-lymphocyte ratio (NLR) in predicting the prolonged duration of hospitalization in maxillofacial infections, we performed a retrospective study by collecting paper records data from 108 patients who met our inclusion criteria. The patients were divided into two groups according to the duration of hospitalization (group A < 5 days and group B ≥ 5 days). The predictor variables were CRP, WBC, and NLR, and the outcome variable was the duration of hospitalization. This study confirmed a positive linear correlation (p < 0.001) between the predictors and the outcome variable. The optimal cut-off values for WBC are 11,030 white blood cells/μL and 63 mg/L for CRP. Levels that exceed these optimal values predict a duration of hospitalization of over (≥) 5 days. Serum WBC and CRP on admission may predict the duration of hospitalization in patients with MFI. Full article

(This article belongs to the Special Issue Current Challenges in Clinical Dentistry)

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12 pages, 938 KiB

Open AccessArticle

Orthodontic Treatment Does Not Affect Frontal Sinus Development in Female Adults: A Clinical Study

by Masaki Sawada, Saya Suetake, Hiroshi Yamada, Masaaki Higashino, Susumu Abe and Eiji Tanaka

J. Clin. Med. 2023, 12(3), 778; https://doi.org/10.3390/jcm12030778 - 18 Jan 2023

Cited by 1 | Viewed by 1634

Abstract

Frontal sinus growth is gradual and lasts until post-puberty. However, the influence of biomechanical stimuli, such as orthodontic treatment, on frontal sinus development after the growth period has ended remains unclear. This study was designed to elucidate the impact of orthodontic treatment on [...] Read more.

Frontal sinus growth is gradual and lasts until post-puberty. However, the influence of biomechanical stimuli, such as orthodontic treatment, on frontal sinus development after the growth period has ended remains unclear. This study was designed to elucidate the impact of orthodontic treatment on the frontal sinus morphology of adult females. Sixty women were included and divided into three groups, based on the Frankfort mandibular plane angle. All participants underwent computed tomography and lateral cephalometry before and after treatment. Although two participants exhibited frontal sinus agenesis, most exhibited a bilaterally symmetric frontal sinus without fusion. The frontal sinus width and height were almost similar, irrespective of the vertical skeletal pattern, where the frontal sinus depth was significantly larger in the average mandibular plane angle group than in the low- and high-angle groups. Furthermore, the sinus volume in the low-angle group was likely smaller than that in the average and high-angle groups. On comparing pre-treatment and post-treatment measurements, minimal or no changes to the frontal sinus dimension were detected after treatment. In conclusion, orthodontic treatment did not affect frontal sinus development after the end of growth. Full article

(This article belongs to the Special Issue Current Challenges in Clinical Dentistry)

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15 pages, 2601 KiB

Open AccessArticle

Associations between Periodontitis and COPD: An Artificial Intelligence-Based Analysis of NHANES III

by Andreas Vollmer, Michael Vollmer, Gernot Lang, Anton Straub, Veronika Shavlokhova, Alexander Kübler, Sebastian Gubik, Roman Brands, Stefan Hartmann and Babak Saravi

J. Clin. Med. 2022, 11(23), 7210; https://doi.org/10.3390/jcm11237210 - 4 Dec 2022

Cited by 14 | Viewed by 3812

Abstract

A number of cross-sectional epidemiological studies suggest that poor oral health is associated with respiratory diseases. However, the number of cases within the studies was limited, and the studies had different measurement conditions. By analyzing data from the National Health and Nutrition Examination [...] Read more.

A number of cross-sectional epidemiological studies suggest that poor oral health is associated with respiratory diseases. However, the number of cases within the studies was limited, and the studies had different measurement conditions. By analyzing data from the National Health and Nutrition Examination Survey III (NHANES III), this study aimed to investigate possible associations between chronic obstructive pulmonary disease (COPD) and periodontitis in the general population. COPD was diagnosed in cases where FEV (1)/FVC ratio was below 70% (non-COPD versus COPD; binary classification task). We used unsupervised learning utilizing k-means clustering to identify clusters in the data. COPD classes were predicted with logistic regression, a random forest classifier, a stochastic gradient descent (SGD) classifier, k-nearest neighbors, a decision tree classifier, Gaussian naive Bayes (GaussianNB), support vector machines (SVM), a custom-made convolutional neural network (CNN), a multilayer perceptron artificial neural network (MLP), and a radial basis function neural network (RBNN) in Python. We calculated the accuracy of the prediction and the area under the curve (AUC). The most important predictors were determined using feature importance analysis. Results: Overall, 15,868 participants and 19 feature variables were included. Based on k-means clustering, the data were separated into two clusters that identified two risk characteristic groups of patients. The algorithms reached AUCs between 0.608 (DTC) and 0.953% (CNN) for the classification of COPD classes. Feature importance analysis of deep learning algorithms indicated that age and mean attachment loss were the most important features in predicting COPD. Conclusions: Data analysis of a large population showed that machine learning and deep learning algorithms could predict COPD cases based on demographics and oral health feature variables. This study indicates that periodontitis might be an important predictor of COPD. Further prospective studies examining the association between periodontitis and COPD are warranted to validate the present results. Full article

(This article belongs to the Special Issue Current Challenges in Clinical Dentistry)

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14 pages, 7973 KiB

Open AccessArticle

Evaluation of the Tooth Surface after Irradiation with Diode Laser Applied for Removal of Dental Microorganisms from Teeth of Patients with Gingivitis, Using X-ray Photoelectron (XPS) and Optical Profilometry (OP)

by Iga Wawrzyk-Bochenek, Michał Łobacz, Sławomir Wilczyński, Mansur Rahnama, Justyna Szulc, Adam Konka and Anna Wawrzyk

J. Clin. Med. 2022, 11(22), 6840; https://doi.org/10.3390/jcm11226840 - 19 Nov 2022

Cited by 2 | Viewed by 1466

Abstract

Gingivitis is accompanied by microorganisms, including pathogens, which must be eliminated to speed up the treatment of inflammation. Laser irradiation may be one of the safe methods for reducing tissue contamination on the tooth surface. The aim of the study was the assessment [...] Read more.

Gingivitis is accompanied by microorganisms, including pathogens, which must be eliminated to speed up the treatment of inflammation. Laser irradiation may be one of the safe methods for reducing tissue contamination on the tooth surface. The aim of the study was the assessment of the tooth surface in patients with gingivitis after the use of a diode laser to eliminate microorganisms living there. In the first stage of the research, microorganisms were isolated (Candida albicans, C. guilliermondii, Escherichia coli, Haemophilus parainfluenzae, Klebsiella oxytoca, Neisseria subflava, Rothia dentocariosa, Rothia mucilaginosa, Streptococcus pneumoniae) from three patients with gingivitis, their identification confirmed using the MALDI-TOF MS technique (matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry). Then, the irradiation process with a diode laser was optimized to a wavelength of 810 nm ± 10 nm in five variants to reduce microorganisms on the tooth. The tooth surface was analyzed by X-ray photoelectron spectroscopy (XPS) and optical profilometry (OP) before and after irradiation. 103 to 106 CFU were detected on a 0.4 cm² tooth area. Nine types of bacteria and two types of fungi dominated among the microorganisms. The laser at the most effective biocidal dose of 25 W/15.000 Hz/10 µs, average = 3.84 W, with three uses after 15 s, increased the reduction of fungi from 57.97% to 93.80%, and bacteria from 30.67% to 100%. This dose also caused a decrease in the degree of oxidation and in the effect of smoothing on the treated surfaces. Full article

(This article belongs to the Special Issue Current Challenges in Clinical Dentistry)

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Review

Jump to: Research, Other

12 pages, 622 KiB

Open AccessReview

Current Status of the Management of Idiopathic Condylar Resorption/Progressive Condylar Resorption—A Scoping Review

by Eiji Tanaka and Louis G. Mercuri

J. Clin. Med. 2024, 13(13), 3951; https://doi.org/10.3390/jcm13133951 - 5 Jul 2024

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Abstract

The temporomandibular joint (TMJ) is a complex synovial joint shrouded in mystery, as the etiology of many TMJ disorders are unsolved. Idiopathic/progressive condylar resorption (ICR/PCR) is one such TMJ disorder characterized by a gradually deteriorating mandibular condylar mass, resulting in severe mandibular retrognathia, [...] Read more.

The temporomandibular joint (TMJ) is a complex synovial joint shrouded in mystery, as the etiology of many TMJ disorders are unsolved. Idiopathic/progressive condylar resorption (ICR/PCR) is one such TMJ disorder characterized by a gradually deteriorating mandibular condylar mass, resulting in severe mandibular retrognathia, which often accompanied by clockwise rotation of mandible and an anterior open bite. Since the etiology of the ICR/PCR remains unclear, no definitive prevention or management options have been established. To date, various symptomatic non-surgical, surgical, and salvage management options have been developed and reported. To understand the current status of the ICR/PCR management options, this article provides an overview of the options presently reported in the literature to reduce its TMJ symptoms and improve mandibular function and form. Full article

(This article belongs to the Special Issue Current Challenges in Clinical Dentistry)

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12 pages, 255 KiB

Open AccessReview

Advancements in Methods of Classification and Measurement Used to Assess Tooth Mobility: A Narrative Review

by Gi Youn Kim, Sunjai Kim, Jae-Seung Chang and Se-Wook Pyo

J. Clin. Med. 2024, 13(1), 142; https://doi.org/10.3390/jcm13010142 - 27 Dec 2023

Cited by 1 | Viewed by 2712

Abstract

Evaluating tooth mobility is clinically significant, not only for diagnosing periodontal tissues but also in determining the overall periodontal treatment plan. Numerous studies related to tooth mobility have been conducted over the years, including the proposal of various classifications as well as the [...] Read more.

Evaluating tooth mobility is clinically significant, not only for diagnosing periodontal tissues but also in determining the overall periodontal treatment plan. Numerous studies related to tooth mobility have been conducted over the years, including the proposal of various classifications as well as the development of electronic devices for objective measurement. However, there is still no consensus on the measurement methods and criteria for assessing tooth mobility. In this study, we provide a comprehensive review of past and current tooth mobility classification and measurement methods. In order to propose a new method to intuitively evaluate tooth mobility based on previous studies, a digital approach capable of recording tooth micromovements induced by dynamic load should be considered. Full article

(This article belongs to the Special Issue Current Challenges in Clinical Dentistry)

16 pages, 792 KiB

Open AccessReview

Current Progress and Challenges of Using Artificial Intelligence in Clinical Dentistry—A Narrative Review

by Zinovia Surlari, Dana Gabriela Budală, Costin Iulian Lupu, Carmen Gabriela Stelea, Oana Maria Butnaru and Ionut Luchian

J. Clin. Med. 2023, 12(23), 7378; https://doi.org/10.3390/jcm12237378 - 28 Nov 2023

Cited by 9 | Viewed by 3010

Abstract

The concept of machines learning and acting like humans is what is meant by the phrase “artificial intelligence” (AI). Several branches of dentistry are increasingly relying on artificial intelligence (AI) tools. The literature usually focuses on AI models. These AI models have been [...] Read more.

The concept of machines learning and acting like humans is what is meant by the phrase “artificial intelligence” (AI). Several branches of dentistry are increasingly relying on artificial intelligence (AI) tools. The literature usually focuses on AI models. These AI models have been used to detect and diagnose a wide range of conditions, including, but not limited to, dental caries, vertical root fractures, apical lesions, diseases of the salivary glands, maxillary sinusitis, maxillofacial cysts, cervical lymph node metastasis, osteoporosis, cancerous lesions, alveolar bone loss, the need for orthodontic extractions or treatments, cephalometric analysis, age and gender determination, and more. The primary contemporary applications of AI in the dental field are in undergraduate teaching and research. Before these methods can be used in everyday dentistry, however, the underlying technology and user interfaces need to be refined. Full article

(This article belongs to the Special Issue Current Challenges in Clinical Dentistry)

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17 pages, 1489 KiB

Open AccessReview

Are Local Drug Delivery Systems a Challenge in Clinical Periodontology?

by Dana Gabriela Budală, Ionut Luchian, Monica Tatarciuc, Oana Butnaru, Adina Oana Armencia, Dragoș Ioan Virvescu, Monica Mihaela Scutariu and Darian Rusu

J. Clin. Med. 2023, 12(12), 4137; https://doi.org/10.3390/jcm12124137 - 19 Jun 2023

Cited by 5 | Viewed by 3642

Abstract

Placing antimicrobial treatments directly in periodontal pockets is an example of the local administration of antimicrobial drugs to treat periodontitis. This method of therapy is advantageous since the drug concentration after application far surpasses the minimum inhibitory concentration (MIC) and lasts for a [...] Read more.

Placing antimicrobial treatments directly in periodontal pockets is an example of the local administration of antimicrobial drugs to treat periodontitis. This method of therapy is advantageous since the drug concentration after application far surpasses the minimum inhibitory concentration (MIC) and lasts for a number of weeks. As a result, numerous local drug delivery systems (LDDSs) utilizing various antibiotics or antiseptics have been created. There is constant effort to develop novel formulations for the localized administration of periodontitis treatments, some of which have failed to show any efficacy while others show promise. Thus, future research should focus on the way LDDSs can be personalized in order to optimize future clinical protocols in periodontal therapy. Full article

(This article belongs to the Special Issue Current Challenges in Clinical Dentistry)

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Other

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13 pages, 7558 KiB

Open AccessCase Report

Severe Maxillary Protrusion Treated with Surgically Assisted Rapid Maxillary Expansion

by Sonoko Okuhashi, Masaru Kobayashi and Eiji Tanaka

J. Clin. Med. 2024, 13(14), 4149; https://doi.org/10.3390/jcm13144149 - 16 Jul 2024

Viewed by 1084

Abstract

In this case, surgically assisted rapid maxillary expansion (SARME) was successfully adopted to treat a skeletal maxillary protrusion with large overjet and severe crowding. The female patient, aged 25 years and 11 months, was diagnosed with skeletal maxillary protrusion with severe crowding and [...] Read more.

In this case, surgically assisted rapid maxillary expansion (SARME) was successfully adopted to treat a skeletal maxillary protrusion with large overjet and severe crowding. The female patient, aged 25 years and 11 months, was diagnosed with skeletal maxillary protrusion with severe crowding and excessive overjet associated with labially inclined maxillary central incisors. After achieving sufficient space for surgical incision between bilateral maxillary central incisors, the SARME was performed. A total of 8.0 mm lateral expansion of the maxilla was completed. At 48 days after surgery, the Hyrax appliance was replaced with an Anchor-Lock system used as an external surgical stent and skeletal anchorage for maxillary group distalization, and the distal movement of the maxillary molars was initiated without waiting for bone healing of the separated midpalatal suture by SARME. Twenty-five months’ treatment, including surgical preparation, achieved an acceptable and stable occlusion with adequate interincisal relationship. The occlusion was much more stable with a little relapse through more than 4 years’ retention period. In conclusion, SARME followed by the Anchor-Lock system might lead to favorable occlusal outcome in the long term without any relapses. Full article

(This article belongs to the Special Issue Current Challenges in Clinical Dentistry)

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