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Advances in Endoscopic, Surgical, and Interventional Radiological Management of Gastrointestinal...
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Advances in Endoscopic, Surgical, and Interventional Radiological Management of Gastrointestinal Diseases

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Medical Research".

Deadline for manuscript submissions: 29 November 2024 | Viewed by 2419

Special Issue Editor

Dr. Beata Jabłońska

E-Mail Website
Guest Editor
Department of Digestive Tract Surgery, Medical University of Silesia, Katowice, Poland
Interests: gastrointestinal surgery; oncological surgery; vascular surgery; gastroenterology; angiology; oncology; nutritional status; nutrition
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Gastrointestinal diseases encompass a wide spectrum of inflammatory and neoplastic conditions. They may be chronic as well as acute disorders. Recently, significant progress in the diagnostic and therapeutic field has been noted. A higher number of patients can now be treated using less invasive endoscopic and radiologic approaches, such as endoscopic prosthesis for biliary and pancreatic strictures and fistulas, endoscopic cystogastrostomy for post-inflammatory pancreatic pseudocysts, and endoscopic necrosectomy for pancreatic necrosis. On the other hand, some patients require advanced surgery, including open, laparoscopic, and robotic approaches. In recent years, complex surgical procedures, including esophageal, gastric, bowel, pancreatic, and hepatic resections for gastrointestinal neoplasms, have been evaluated. In addition, techniques for interventional radiological procedures, such as percutaneous drainage of biliary tract and intra-abdominal abscess, transarterial embolization, and stent graft implantation for visceral true and post-inflammatory and postoperative pseudoaneurysms, have improved. Due to advances in multimodal oncological management, including chemotherapy, radiotherapy, immunotherapy, and complex multivisceral surgery (including venous and arterial concomitant resections), radical treatment leading to better prognosis and longer survival may be possible for an increasing number of patients.

Surgeons, gastroenterologists, oncologists, and radiologists, as well as all the physicians involved in the management of gastrointestinal diseases, are invited to contribute to this Special Issue.

Dr. Beata Jabłońska
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Life is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • gastrointestinal disease
  • endoscopic cystogastrostomy
  • endoscopic biliary prosthesis
  • endoscopic pancreatic prosthesis
  • endoscopic necrosectomy
  • esophagectomy
  • gastrectomy
  • bowel resection
  • colectomy
  • pancreatectomy
  • hepatectomy
  • liver transplantation
  • gastroenterology
  • surgery
  • interventional radiology

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Published Papers (3 papers)

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Research

15 pages, 1819 KiB  
Article
What We Know So Far About ECG for Pancreatic Pseudocysts
by Paulina Kluszczyk, Beata Jabłońska, Michał Serafin, Aleksandra Tobiasz, Tomasz Kowalczyk, Sebastian Maślanka, Mateusz Chapuła, Piotr Wosiewicz and Sławomir Mrowiec
Life 2024, 14(11), 1419; https://doi.org/10.3390/life14111419 - 4 Nov 2024
Viewed by 439
Abstract
Background: Endoscopic cysto-gastrostomy (ECG) has become the treatment of choice for pancreatic pseudocysts (PPCs). Endoscopic drainage of PPCs requires the creation of an anastomosis between the lumen of the PPCs and the lumen of the gastrointestinal tract. Various types of stents are used [...] Read more.
Background: Endoscopic cysto-gastrostomy (ECG) has become the treatment of choice for pancreatic pseudocysts (PPCs). Endoscopic drainage of PPCs requires the creation of an anastomosis between the lumen of the PPCs and the lumen of the gastrointestinal tract. Various types of stents are used for this purpose. The aim of the study is to compare the indications, quantity, and results of using double pigtail plastic stents (DPPSs) and lumen-apposing fully covered metal stents (LAMSs) in ECG. Methods: A retrospective analysis was conducted of 39 patients (24 men, 15 women) treated for PPCs in the Department of Digestive Tract Surgery and the Department of Gastroenterology and Hepatology between October 2018 and February 2023. The mean age of patients was 51.13 (28–77). Data about etiology, cyst diameter, type, and complications of the stents were collected. Results: DPPSs were placed in smaller cysts (108 vs. 140 millimeters, p = 0.04) and were maintained for a longer duration compared to LAMSs (106 vs. 34 days, p = 0.001). Cyst recurrence was reported less frequently in patients with a LAMS (0 (0%) vs. 4 (19.05%), p = 0.05) and the therapeutic success was non-significantly higher in the LAMS group compared to the DPPS group (100% vs. 85.71%), p = 0.095. Conclusions: Both DPPSs and LAMSs are characterized by high therapeutic success and low complication rates in patients undergoing ECG for PPCs. Full article
(This article belongs to the Special Issue Advances in Endoscopic, Surgical, and Interventional Radiological Management of Gastrointestinal Diseases)
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12 pages, 1132 KiB  
Article
Trypsin and Trypsinogen Activation Peptide in the Prediction of Severity of Acute Pancreatitis
by Andreas Allemann, Sebastian M. Staubli and Christian A. Nebiker
Life 2024, 14(9), 1055; https://doi.org/10.3390/life14091055 - 23 Aug 2024
Viewed by 864
Abstract
Objectives: To assess the predictive value of serum trypsin and trypsinogen activation peptide (TAP) for the severity of AP through a single center cohort study as well as a systematic review of the current literature. Methods: A literature search was conducted using Medline [...] Read more.
Objectives: To assess the predictive value of serum trypsin and trypsinogen activation peptide (TAP) for the severity of AP through a single center cohort study as well as a systematic review of the current literature. Methods: A literature search was conducted using Medline (PubMed), EMBASE and the Cochrane Central Register. A total of 142 patients with acute pancreatitis (AP) were included in the cohort study and parameters of the revised Atlanta criteria of 2012 and the APACHE II were assessed. Results: The review showed promising results for the predictive value of serum trypsinogen-2 but conflicting results for serum TAP and trypsin. In the cohort study, patients were observed for 4 days after diagnosis of AP; 9 patients had severe AP, 35 patients had moderate AP and 81 patients had mild AP. The ratio of the geometric mean of severe vs. mild AP for trypsin was 0.72 (95% CI: 0.51–1.00), p = 0.053 and, for TAP, 0.74 (95% CI: 0.54–1.01), p = 0.055, respectively. Conclusions: The cohort study showed an inverse correlation of serum levels of TAP and trypsin with severity of AP. Serum TAP and trypsin have an inferior predictive value of severity of AP compared to the clinical APACHE II score. Full article
(This article belongs to the Special Issue Advances in Endoscopic, Surgical, and Interventional Radiological Management of Gastrointestinal Diseases)
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13 pages, 1577 KiB  
Article
Endoscopic Surveillance after (Procto)Colectomy with Gastrointestinal Reconstruction in Patients with Familial Adenomatous Polyposis (FAP)—Principles, Goals and Practical Aspects Based on 12 Years of Observation
by Jarosław Cwaliński, Wiktoria Zasada, Hanna Cholerzyńska, Wiktoria Andrzejewska, Hanna Michalak, Tomasz Banasiewicz and Jacek Paszkowski
Life 2024, 14(8), 1000; https://doi.org/10.3390/life14081000 - 12 Aug 2024
Viewed by 854
Abstract
(1) Background: Familial adenomatous polyposis (FAP) is a hereditary condition characterized by the development of numerous adenomas in the large intestine, often necessitating colectomy due to an elevated risk of colorectal cancer. Despite surgical intervention, adenomas frequently recur, underscoring the importance of ongoing [...] Read more.
(1) Background: Familial adenomatous polyposis (FAP) is a hereditary condition characterized by the development of numerous adenomas in the large intestine, often necessitating colectomy due to an elevated risk of colorectal cancer. Despite surgical intervention, adenomas frequently recur, underscoring the importance of ongoing surveillance. This study evaluates the outcomes of a 12-year endoscopic follow-up after colectomy and gastrointestinal reconstruction for FAP. (2) Methods: A retrospective analysis was conducted on 41 FAP patients who underwent at least one postoperative endoscopic examination. Assessments of the pouch or rectum were performed every 12–18 months following ileorectal anastomosis and every 18–24 months after ileal pouch–anal anastomosis. Follow-up biopsies were assessed using the adopted Spigelman classification. (3) Results: Postoperative pathology revealed invasive colorectal cancer in three patients. Abdominoperineal resection was performed in two cases due to secondary invasive carcinoma, and one T1 tumor was radically removed with ESD. One patient underwent radical pouch excision following a nodal pelvic recurrence of rectal cancer. Over a 12-year observation period, the mean Spigelman score increased by 2 points, and the proportion of patients with low-grade polypoid lesions decreased. The quantity or size of polyps increased in 24 patients, decreased in 8 patients, and remained stable in 9 patients. In four patients, granular, laterally spreading tumors were discovered in the rectal stump. (4) Conclusions: Regular endoscopic surveillance in FAP patients facilitates early identification of neoplastic and inflammatory changes. The downstaging potential highlights the effectiveness of early interventions. While the Spigelman classification assessed polyps well, it did not predict cancer occurrence. A notable number of patients had invasive cancer at the time of surgery, underscoring the importance of early surgical qualification, which is particularly crucial for identifying upstaging or secondary cancer. Full article
(This article belongs to the Special Issue Advances in Endoscopic, Surgical, and Interventional Radiological Management of Gastrointestinal Diseases)
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