Advancements in Total Joint Arthroplasty

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Medical Research".

Deadline for manuscript submissions: 20 December 2024 | Viewed by 1973

Special Issue Editors


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Guest Editor
Guglielmo da Saliceto Polichirurgico Hospital AUSL Piacenza, 29121 Piacenza, Italy
Interests: knee arthroplasty; hip arthroplasty; trauma
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Guest Editor
1. Robotic Prosthetic Surgery Unit—Sports Traumatology Unit, Fondazione Poliambulanza Hospital, 25124 Brescia, Italy
2. Department of Orthopedics, Catholic University of the Sacred Heart, 20123 Rome, Italy
Interests: total arthroplasty; hip and knee arthroplasty

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1. Fondazione Poliambulanza Istituto Ospedaliero, Via Leonida Bissolati, 57, 25124 Brescia, BS, Italy
2. Istituto Universitario Studi Superiori, Palazzo del Broletto, Piazza della Vittoria, 15, 27100 Pavia, PV, Italy
Interests: KAT
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Sezione di Chirurgia Protesica ad Indirizzo Robotico, Unità di Traumatologia dello Sport, Brescia, Italy
Interests: total knee arthroplasty; orthopedics; adult reconstructive surgery; robotic surgery
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue represents a deep dive into the field of total joint arthroplasty, offering a detailed exploration of complex management strategies and new perspectives for the future. This collection covers a wide range of topics, from the analysis of hip and knee replacements to the latest innovations. These articles shed a clear light on the ongoing evolution of joint arthroplasty, revealing challenges faced in areas like implant materials, infection prevention, and long-term outcomes for patients undergoing these procedures.

We encourage the submission of original basic, translational, and clinical research and review articles on the following topics related to total joint arthroplasty of the hip, knee, and shoulder:

  • Robotic and technology-assisted joint replacement.
  • Periprosthetic joint infection—prevention, diagnosis, and therapeutics.
  • Biomaterials and implant design.
  • Tissue engineering.
  • Muscle strengthening and conditioning.
  • Implant designs.
  • Edema and pain.

We look forward to your contributions.

Dr. Corrado Ciatti
Dr. Luca Andriollo
Prof. Dr. Francesco Benazzo
Dr. Stefano Marco Paolo Rossi
Guest Editors

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Keywords

  • robotic and technology-assisted joint replacement
  • periprosthetic joint infection—prevention, diagnosis, and therapeutics
  • biomaterials and implant design
  • tissue engineering
  • muscle strengthening and conditioning
  • implant designs
  • edema and pain

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Published Papers (3 papers)

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Research

13 pages, 668 KiB  
Article
Advancements and Strategies in Robotic Planning for Knee Arthroplasty in Patients with Minor Deformities
by Giacomo Capece, Luca Andriollo, Rudy Sangaletti, Roberta Righini, Francesco Benazzo and Stefano Marco Paolo Rossi
Life 2024, 14(12), 1528; https://doi.org/10.3390/life14121528 - 21 Nov 2024
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Abstract
Knee arthroplasty, commonly performed to treat osteoarthritis, necessitates precise surgical techniques for optimal outcomes. The introduction of systems such as the Persona Knee System (Zimmer Biomet, Warsaw, IN, USA) has revolutionized knee arthroplasty, promising enhanced precision and better patient outcomes. This study investigates [...] Read more.
Knee arthroplasty, commonly performed to treat osteoarthritis, necessitates precise surgical techniques for optimal outcomes. The introduction of systems such as the Persona Knee System (Zimmer Biomet, Warsaw, IN, USA) has revolutionized knee arthroplasty, promising enhanced precision and better patient outcomes. This study investigates the application of robotic planning specifically in knee prosthetic surgeries, with a focus on Persona Knee System prostheses. We conducted a retrospective analysis of 300 patients who underwent knee arthroplasty using the Persona Knee System between January 2020 and November 2023, including demographic data, surgical parameters, and preoperative imaging. Robotic planning was employed to simulate surgical procedures. The planning process integrated preoperative imaging data from a specific program adopted for conducting digital preoperative planning, and statistical analyses were conducted to assess correlations between patient characteristics and surgical outcomes. Out of 300 patients, 85% presented with minor deformities, validating the feasibility of robotic planning. Robotic planning demonstrated precise prediction of optimal arthroplasty sizes and alignment, closely aligning with preoperative imaging data. This study highlights the potential benefits of robotic planning in knee arthroplasty surgeries, particularly in cases with minor deformities. By leveraging preoperative imaging data and integrating advanced robotic technologies, surgeons can improve precision and efficacy in knee arthroplasty. Moreover, robotic technology allows for a reduced level of constraint in the intraoperative choice between Posterior-Stabilized and Constrained Posterior-Stabilized liners compared with an imageless navigated procedure. Full article
(This article belongs to the Special Issue Advancements in Total Joint Arthroplasty)
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9 pages, 597 KiB  
Article
Therapy for Non-Diabetic Foot Infections After Orthopedic Foot and Ankle Surgery: The Duration of Post-Debridement Antibiotic Treatment Does Not Alter Failure Risk
by Martina Scherer, Laura Soldevila-Boixader, İnci Yιldιz, Franziska C. S. Altorfer, Pascal R. Furrer, Silvan Beeler, Stephan H. Wirth, Arnd Viehöfer and İlker Uçkay
Life 2024, 14(11), 1509; https://doi.org/10.3390/life14111509 - 20 Nov 2024
Viewed by 398
Abstract
Despite growing numbers of scientific publications on the optimal antibiotic treatment for diabetic foot infections, the data on the adult population with non-diabetic (postsurgical) foot infections is limited. Therefore, one of the largest single-center databases at the Balgrist University Hospital in Zurich, Switzerland, [...] Read more.
Despite growing numbers of scientific publications on the optimal antibiotic treatment for diabetic foot infections, the data on the adult population with non-diabetic (postsurgical) foot infections is limited. Therefore, one of the largest single-center databases at the Balgrist University Hospital in Zurich, Switzerland, was established between January 2014 and August 2022. Using a case–control study design, we retrospectively investigated failures of combined surgical and antibiotic therapy for surgical site foot infections (SSIs). Overall, 17.4% of the episodes experienced therapeutic failures, particularly in patients with infected ankle prostheses. However, age, biological sex, pathogens, the duration of post-debridement antibiotic treatment, the number of surgical debridements, or the use of negative-pressure wound care altered the failure risk. In the multivariate logistic regression analyses, the duration of postsurgical antibiotic use was completely indifferent (as a continuous variable with an odds ratio of 1.0 and a 95% confidence interval ranging from 0.96 to 1.03) when stratified into inter-tertiary groups. Our findings suggest that shorter courses of systemic antibiotics may be appropriate in non-diabetic adults, supporting better antibiotic stewardship. Ongoing randomized controlled trials are under way to investigate which patients might safely receive shorter antibiotic treatments for surgical site infections following elective foot and ankle procedures. Full article
(This article belongs to the Special Issue Advancements in Total Joint Arthroplasty)
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10 pages, 507 KiB  
Article
Predictors of Persistent Pain after Total Knee Arthroplasty
by Ali H. Alyami, Mohammed A. Alkhotani, Abdulaziz Abdullah Alsiraihi, Abdulaziz Farouk Y. Bokhari, Mohammed Majed Bukhari, Omar E. Hetta, Hassan O. Bogari and Mohamed Eldigire Ahmed
Life 2024, 14(10), 1300; https://doi.org/10.3390/life14101300 - 14 Oct 2024
Viewed by 1027
Abstract
Background: Total knee arthroplasty (TKA) is an orthopedic procedure performed on patients with severe knee pain and advanced knee conditions, such as osteoarthritis and rheumatoid arthritis, in order to restore joint function. Despite the procedure’s high success rates, persistent postoperative pain (PPP) remains [...] Read more.
Background: Total knee arthroplasty (TKA) is an orthopedic procedure performed on patients with severe knee pain and advanced knee conditions, such as osteoarthritis and rheumatoid arthritis, in order to restore joint function. Despite the procedure’s high success rates, persistent postoperative pain (PPP) remains a significant complication, affecting a substantial proportion of patients. Identifying predictors of PPP is crucial for improving patient outcomes and satisfaction. Methods: A retrospective analytic study was conducted, reviewing the medical records of patients who underwent unilateral or bilateral TKA at King Abdulaziz Medical City. The data collection focused on demographics, comorbidities, clinical presentations, surgical details, and postoperative outcomes. Data were analyzed using JMP software. A p-value of less than 0.05 was considered statistically significant. Results: This study included 838 patients, predominantly female (71.5%), with an average age of 65.4 years. Osteoarthritis was the primary reason for surgery (98.3%). The mean preoperative pain score was 3.4, and the average pain duration prior to surgery was 6.2 years. We identified dyslipidemia as a significant predictor of PPP (OR 1.40, p = 0.042), while we found younger age to be a significant predictor (OR 0.979, 95% CI 0.967–0.991, p = 0.001). Other factors such as gender, diabetes, hypertension, cardiovascular disease, anxiety disorder, mood disorder, tobacco use, chronic kidney disease, chronic lung disease, and BMI were not significant predictors of PPP. Conclusion: This study identifies younger age and dyslipidemia as significant predictors of persistent postoperative pain and improved outcomes following total knee arthroplasty Further research is needed to validate these results in diverse populations and settings, with the objective should be to refine preoperative counseling and postoperative pain management protocols. Full article
(This article belongs to the Special Issue Advancements in Total Joint Arthroplasty)
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