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Life
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Causes and Effects of Nutritional Changes
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Causes and Effects of Nutritional Changes

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Reproductive and Developmental Biology".

Deadline for manuscript submissions: closed (25 November 2022) | Viewed by 5286

Special Issue Editors

Prof. Dr. Alexandra M. Crǎciun

E-Mail Website
Guest Editor
Department of Biochemistry, University of Medicine and Pharmacy Iuliu Hatieanu Cluj-Napoca, Cluj-Napoca, Romania
Interests: bone metabolism; vitamin D; biomedical science; cartilage arthritis; rheumatoid arthritis; bone; osteoblasts; vitamin K; atherosclerosis; bone research; clinical chemistry; clinical trials; nutritional biochemistry; bone mineral density; osteoporosis; cardiovascular risk; hip fracture; bone mineralization; myocardial infarction; calcium; metabolic syndrome; lipids; lipoproteins; cardiovascular disease; diabetes; chronic inflammation; chronic intestinal disease; microbiota; short-chain fatty acids
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. Gabriela C. Zaharie

E-Mail Website
Guest Editor
Department of Mother and child, Iuliu Hatieganu University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania
Interests: neonatal intensive care; nutrition of the newborn; follow-up of the newborn at risk

Special Issue Information

Dear colleagues,

Nutrition and the gastrointestinal environment have significant effects on life in infancy, adulthood, and later in life. This Special Issue presents the latest research and the research that is currently under review in the field of human nutritional status and considers fat-soluble vitamins, the microbiota, and inflammatory status. Deficiencies in fat-soluble vitamins and inflammation related to regulatory proteins in energy metabolism and bone development  have been analyzed in humans. The metabolic and inflammatory status of preterm infants is also one of the topics we aimed to consider. This Special Issue presents recent research on fat digestion and fatty acid metabolism in postpartum gut adaptation, the development of local and systemic immune defenses, and the regulation of inflammatory responses.

Prospective authors should first send a brief abstract or tentative title to the Editorial Office. Authors are encouraged to submit full manuscripts if the editor deems the topic suitable for inclusion in the Special Issue.

Prof. Dr. Alexandra Crǎciun
Prof. Dr. Gabriela C. Zaharie
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Life is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • vitamin D
  • vitamin K
  • GLA proteins
  • C reactive protein
  • IL-6, IL-1 beta, TNF alpha
  • short-chain fatty acids (SCFA)

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Published Papers (2 papers)

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Research

13 pages, 860 KiB  
Article
Higher Dietary Vitamin D Intake Influences the Lipid Profile and hs-CRP Concentrations: Cross-Sectional Assessment Based on The National Health and Nutrition Examination Survey
by Zahra Hariri, Hamed Kord-Varkaneh, Noura Alyahya, Kousalya Prabahar, Mihnea-Alexandru Găman and Ahmed Abu-Zaid
Life 2023, 13(2), 581; https://doi.org/10.3390/life13020581 - 19 Feb 2023
Cited by 6 | Viewed by 2651
Abstract
Background. An unanswered question in the field of nutrition is whether there is an association between vitamin D intake and the lipid profile in adults. We conducted this cross-sectional study in order to investigate the impact of vitamin D intake on the lipid [...] Read more.
Background. An unanswered question in the field of nutrition is whether there is an association between vitamin D intake and the lipid profile in adults. We conducted this cross-sectional study in order to investigate the impact of vitamin D intake on the lipid profile of adults in the context of the 2017–2018 National Health and Nutrition Examination Survey (NHANES). Methods. Serum lipids and high-sensitivity C-reactive protein (hs-CRP) concentrations and the Vitamin D intake in 2588 people aged 19 to 70 years was collected using laboratory analysis and 24-h recall, respectively. The one-way ANOVA test was used to compare quantitative variables and the chi-squared test was used to compare qualitative ones. Multivariate logistic regression for three models was performed to assess the odds ratio (OR) of high total cholesterol (TC) (>200 mg/dL), triglycerides (TG) (>150 mg/dL), low-density lipoprotein cholesterol (LDL-C) (>115 mg/dL), high-density lipoprotein cholesterol (HDL-C) (<40 mg/dL) and hs-CRP (>1 mg/l) based on the tertiles of dietary vitamin D (D2 + D3) intake. Results. After adjusting for age, sex, race, body mass index, serum 25-hydroxyvitamin D2, alcohol intake, energy intake, protein intake, carbohydrate intake, fiber intake and fat intake, individuals in the tertile with the highest versus lowest vitamin D intake (>1 mcg/day vs. <0.10 mcg/day) had lower odds of displaying elevated TC, LDL-C and hs-CRP concentrations (OR 0.57; CI: 0.37 to 0.88; P-trend: 0.045, OR 0.59; CI: 0.34 to 1.01; P-trend: 0.025 and OR 0.67; CI: 0.45 to 0.99; P-trend: 0.048, respectively). Based on the results of the logistic regression, no correlation between vitamin D intake and changes in TG or HDL-C values was noted. Conclusions. Our cross-sectional study indicates that higher dietary vitamin D (D2 + D3) intake is associated with lower TC, LDL-C and hs-CRP levels. No relationship between dietary vitamin D intake and TG or HDL-C values was detected. Further large-scale randomized trials are needed to evaluate the actual association between dietary vitamin D intake and the lipid profile. Full article
(This article belongs to the Special Issue Causes and Effects of Nutritional Changes)
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17 pages, 2688 KiB  
Article
Neonatal Antibiotic Treatment Can Affect Stool Pattern and Oral Tolerance in Preterm Infants
by Diana Verónica Reyes-García, Arturo Alejandro Canul-Euan, María Antonieta Rivera-Rueda, Claudia Edith Cruz-Alvarado, Luisa Bertha Bermejo-Martínez, Gabriela Arreola-Ramírez, Guadalupe Cordero-González, Sandra Carrera-Muiños, Juan Daniel Diaz-Valencia, Guadalupe Estrada-Gutiérrez, Claudine Irles and Gabriela Gonzalez-Perez
Life 2022, 12(7), 1043; https://doi.org/10.3390/life12071043 - 13 Jul 2022
Cited by 1 | Viewed by 1998
Abstract
Preterm neonates are at high risk of infectious and inflammatory diseases which require antibiotic treatment. Antibiotics influence neonatal gut microbiome development, and intestinal dysbiosis has been associated with delayed gastrointestinal transit. Neonates who take less time to pass meconium have a better tolerance [...] Read more.
Preterm neonates are at high risk of infectious and inflammatory diseases which require antibiotic treatment. Antibiotics influence neonatal gut microbiome development, and intestinal dysbiosis has been associated with delayed gastrointestinal transit. Neonates who take less time to pass meconium have a better tolerance to enteral feeding. We analyzed the effect of neonatal antibiotic treatment on the stool pattern and oral tolerance in 106 preterm infants < 33 weeks gestational age. Neonates were classified in 3 groups according to neonatal antibiotic (ABT) treatment days: no antibiotics, 3–7 d ABT, and ≥8 d ABT. Preterm infants from the ≥8 d ABT group took longer to pass meconium and to start green and yellow stools, took longer to reach 100 and 150 mL/kg/day, and reached reduced volumes in enteral feeds at day of life 14 and 28 than infants from no ABT and 3–7 d ABT groups. Multiple linear regression models showed that neonatal antibiotic treatment, birth weight, invasive mechanical ventilation, surfactant, enteral feeding start day, neonatal parenteral nutrition, and neonatal fasting days are associated with the stool pattern and oral tolerance in preterm infants. Full article
(This article belongs to the Special Issue Causes and Effects of Nutritional Changes)
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