Biofunctionalized Scaffold in Regenerative Medicine-Series II
A special issue of Materials (ISSN 1996-1944). This special issue belongs to the section "Biomaterials".
Deadline for manuscript submissions: closed (10 November 2022) | Viewed by 3398
Special Issue Editors
Interests: regenerative medicine; stem cells; oral stem cells; biomaterials; extracellular vesicles; exosomes; epithelial- mesenchymal transition
Special Issues, Collections and Topics in MDPI journals
Interests: regenerative medicine; stem cells; biomaterials; extracellular vesicles; exosomes; cardiac regeneration; cardiomyocytes
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The use of a biofunctionalized scaffold with cells and/or soluble factors has emerged as a promising approach in the field of regenerative medicine. A biomaterial refers to a matrix that provides a specific environment and supports growth and development. An ideal scaffold must be biocompatible and nontoxic, and should improve cell viability, cell adhesion, and proliferation. Different scaffolds can be combined with cells, such as mesenchymal stem cells (MSCs), that can promote bone regeneration through differentiation towards the osteogenic lineage or the release of specific soluble factors, or scaffolds can be primed with soluble molecules, including growth factors that can be delivered in the environment, performing therapeutic actions. In recent years, many isolation and culture technologies have been proposed for obtaining a large number of MSCs. These technologies have promoted the application of stem cells in research into disease mechanisms and clinical therapy. MSCs have their own advantages for therapeutic applications, avoiding the risks of immune rejection, directional regulation, and ethical controversy.
Better evaluating the tissue regeneration in scaffold/stem cell models, determining if the emerging imaging technologies fulfill all of the requirements for stem cell therapy research at present, and realizing their improvement and the development of multimodal molecular imaging systems will effectively promote the understanding of stem cell therapy biology and its mechanisms.
The aim of this Special Issue is to provide an overview of ongoing scientific research to better understand the molecular mechanisms involved in tissue regeneration and the evaluation of the aptitude of biofunctionalized scaffolds for future clinical applications. In vitro and/or in vivo studies could have a substantial impact on the development of stem cell-based regeneration strategies and in the identification of key biological regulation processes.
Dr. Francesca Diomede
Dr. Jacopo Pizzicanella
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Materials is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- regenerative medicine
- tissue engineering
- mesenchymal stem cells
- 3D-construct
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue polices can be found here.
