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Metabolites
Special Issues
Nutritional Epidemiology and Metabolic Disorders
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Nutritional Epidemiology and Metabolic Disorders

A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Nutrition and Metabolism".

Deadline for manuscript submissions: 30 November 2024 | Viewed by 4953

Special Issue Editors

Dr. Kijoon Kim

E-Mail Website
Guest Editor
1. Department of Nutritional Sciences, University of Connecticut, Storrs, CT 06269, USA
2. Department of Food and Nutrition, Sookmyung Women’s University, Seoul 04310, Republic of Korea
3. KIM KIJOON BOM Clinic, Lotte Hotel World, Seoul 05554, Republic of Korea
4. BOM Institute of Nutrition and Natural Medicine, Seoul 05554, Republic of Korea
Interests: nutritional epidemiology; antioxidants; medicinal herbs; functional ingredi-ents; public health
Special Issues, Collections and Topics in MDPI journals
Dr. Sanggil Lee

E-Mail Website
Guest Editor
Department of Food Science and Nutrition, Pukyong National University, Busan 48513, Republic of Korea
Interests: marine bioactive compounds; redox medicine; anti-obesity; molecular nutrition; bioactive compound analysis
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

In recent years, the field of nutritional epidemiology has emerged as a crucial discipline in unraveling the intricate interplay between diet, health, and metabolic disorders. Additionally, nutrition is now recognized as a cornerstone of public health, and there is a growing interest in harnessing the potential of antioxidants, medicinal herbs, and functional ingredients in promoting well-being. Given this context, this Special Issue titled ‘Nutritional Epidemiology and Metabolic Disorders’ seeks to collate research papers that explore the dynamic relationship between dietary factors and metabolic health.

The primary focus of this Special Issue is to shed light on the role of nutritional epidemiology in understanding the development, prevention, and management of metabolic disorders, thereby bridging the gap between nutritional science, epidemiology, and public health. Through this, we aim to foster collaboration and knowledge exchange that will contribute to evidence-based dietary recommendations and strategies for preventing and treating metabolic disorders on a global scale.

We invite papers that integrate epidemiological research with nutrition science or employ a multidisciplinary approach to investigate the intricate connections between dietary patterns, nutrient intake, and the prevalence of conditions such as obesity, diabetes, cardiovascular diseases, and more, thus enhancing the understanding of how dietary choices impact metabolic pathways, diseases and overall health. We also encourage submissions that explore the broader implications of nutritional epidemiology in shaping public health policies and promoting healthier lifestyles.

We cordially invite researchers, academicians, and practitioners to submit their original research, reviews as well as perspectives encompassing a broad spectrum of research areas, including but not limited to studies on the epidemiology of specific diets, the effects of antioxidants on oxidative stress, the therapeutic potential of medicinal herbs, and the functional ingredients that hold promise in metabolic disorder management.

Dr. Kijoon Kim
Prof. Dr. Sanggil Lee
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Metabolites is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • nutritional epidemiology
  • antioxidants
  • medicinal herbs
  • functional ingredients
  • public health

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Published Papers (3 papers)

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Research

26 pages, 4637 KiB  
Article
Metabolomic and Physiological Effects of a Cardiorenal Protective Diet Intervention in African American Adults with Chronic Kidney Disease
by Meera J. Patel, Chiamaka Emerenini, Xuan Wang, Teodoro Bottiglieri and Heather Kitzman
Metabolites 2024, 14(6), 300; https://doi.org/10.3390/metabo14060300 - 25 May 2024
Viewed by 1067
Abstract
Chronic kidney disease (CKD) impacts 14% of adults in the United States, and African American (AA) individuals are disproportionately affected, with more than 3 times higher risk of kidney failure as compared to White individuals. This study evaluated the effects of base-producing fruit [...] Read more.
Chronic kidney disease (CKD) impacts 14% of adults in the United States, and African American (AA) individuals are disproportionately affected, with more than 3 times higher risk of kidney failure as compared to White individuals. This study evaluated the effects of base-producing fruit and vegetables (FVs) on cardiorenal outcomes in AA persons with CKD and hypertension (HTN) in a low socioeconomic area. The “Cardiorenal Protective Diet” prospective randomized trial evaluated the effects of a 6-week, community-based FV intervention compared to a waitlist control (WL) in 91 AA adults (age = 58.3 ± 10.1 years, 66% female, 48% income ≤ USD 25K). Biometric and metabolomic variables were collected at baseline and 6 weeks post-intervention. The change in health outcomes for both groups was statistically insignificant (p > 0.05), though small reductions in albumin to creatinine ratio, body mass index, total cholesterol, and systolic blood pressure were observed in the FV group. Metabolomic profiling identified key markers (p < 0.05), including C3, C5, 1-Met-His, kynurenine, PC ae 38:5, and choline, indicating kidney function decline in the WL group. Overall, delivering a directed cardiorenal protective diet intervention improved cardiorenal outcomes in AA adults with CKD and HTN. Additionally, metabolomic profiling may serve as a prognostic technique for the early identification of biomarkers as indicators for worsening CKD and increased CVD risk. Full article
(This article belongs to the Special Issue Nutritional Epidemiology and Metabolic Disorders)
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12 pages, 253 KiB  
Article
Long-Term Adherence to the Mediterranean Diet Reduces 20-Year Diabetes Incidence: The ATTICA Cohort Study (2002–2022)
by Ioanna Kechagia, Thomas Tsiampalis, Evangelia Damigou, Fotios Barkas, Georgia Anastasiou, Evrydiki Kravvariti, Evangelos Liberopoulos, Petros P. Sfikakis, Christina Chrysohoou, Costas Tsioufis, Christos Pitsavos and Demosthenes Panagiotakos
Metabolites 2024, 14(4), 182; https://doi.org/10.3390/metabo14040182 - 25 Mar 2024
Cited by 2 | Viewed by 1585
Abstract
This study aimed to evaluate the association between adherence to the Mediterranean diet and the 20-year incidence of type II diabetes mellitus (T2DM) among adults from the ATTICA study. This study involved a prospective cohort of 3042 men and women recruited at baseline [...] Read more.
This study aimed to evaluate the association between adherence to the Mediterranean diet and the 20-year incidence of type II diabetes mellitus (T2DM) among adults from the ATTICA study. This study involved a prospective cohort of 3042 men and women recruited at baseline from the Attica region in Greece. Sociodemographic, anthropometric, lifestyle, and clinical characteristics were evaluated at baseline and follow-up examinations; adherence to the Mediterranean diet was assessed through the MedDietScore (range 0–55); four Mediterranean diet trajectories were identified (i.e., increasing, decreasing, and sustained high and sustained low adherence levels). For the present analysis, data from 2000 individuals with complete information were used (age 43 ± 13 years; 49% men). Over the 20-year period, 26.3% (95%CI 24.4%, 28.3%) of participants developed T2DM; men exhibited a 1.5-times higher incidence compared to women (p < 0.001). Individuals consistently close to the Mediterranean diet throughout the studied period had an improved glycemic and lipidemic profile (at baseline and at 10-y follow-up) (all p-values < 0.001) and showed a 21% reduction in their 20-year risk of developing T2DM compared to those who were consistently away (RR = 0.79, 95%CI 0.47, 0.86). A long-term adherence to the Mediterranean diet is protective against the onset of T2DM and, therefore, could be incorporated in public health actions for the prevention of the disease. Full article
(This article belongs to the Special Issue Nutritional Epidemiology and Metabolic Disorders)
18 pages, 1116 KiB  
Article
Changes in Intake and Major Food Sources of Carotenoids among U.S. Adults between 2009–2018
by Kijoon Kim, Matthew P. Madore and Ock K. Chun
Metabolites 2024, 14(1), 13; https://doi.org/10.3390/metabo14010013 - 24 Dec 2023
Cited by 2 | Viewed by 1605
Abstract
Large epidemiologic studies suggest that diets rich in total or specific carotenoids are associated with a reduced risk of many chronic diseases. However, there are few studies characterizing trends in dietary carotenoid sources and intake among subgroups of the US adult population in [...] Read more.
Large epidemiologic studies suggest that diets rich in total or specific carotenoids are associated with a reduced risk of many chronic diseases. However, there are few studies characterizing trends in dietary carotenoid sources and intake among subgroups of the US adult population in the previous decade. This study aimed to assess these trends using data from 22,339 adults who participated in NHANES 2009–2018 cycles. Carotenoid intake and major food sources were calculated by linking food consumption data from the 24 h diet recall to an FNDDS 2009–2018 and the USDA’s National Nutrient Database for Standard Reference (Release 28). Among US adults, mean (SE) dietary carotenoid intake was 9687.1 (158.0) mcg/day, and total intake was highest in men, non-smokers, moderate alcohol consumers, supplement users, and those with normal BMI, a PIR ≥ 1.85, and whose physical activity level was considered vigorous (p < 0.05). Carotenoid intake has gradually decreased over the past decade (p-trend: 0.097), especially among White adults (p-trend < 0.05), males (p-trend: 0.062), and those with a PIR of 1.0–1.3 (p-trend: 0.051), as have estimated rates of vitamin A adequacy. Tomatoes, carrots, and spinach were major food sources of carotenoids, and consumption of carrots and tomatoes decreased, while the consumption of lettuce, spinach, and salsa increased from 2009 to 2018. Our results warrant further studies investigating the consequences of the decreased tendencies of carotenoid intake on chronic disease risk, especially focusing on population subgroups exhibiting low or decreasing trends of carotenoid intake status. Full article
(This article belongs to the Special Issue Nutritional Epidemiology and Metabolic Disorders)
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