Sensors, Devices and Systems for Future Food Production and Packaging

A special issue of Micromachines (ISSN 2072-666X). This special issue belongs to the section "E:Engineering and Technology".

Deadline for manuscript submissions: closed (20 March 2022) | Viewed by 28047

Special Issue Editors


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Guest Editor
Biomanufacturing Technology Group, Bioprocessing Technology Institute, Singapore 138668, Singapore
Interests: cultured meat manufacturing; alternative proteins; tissue engineering; bioinks; extracellular matrix

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Guest Editor
BioSense Institute, University of Novi Sad, Novi Sad 21000, Serbia
Interests: biosensors; microfluidics; cultured meat; cellular agriculture; pathogens
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Guest Editor
The Good Food Institute, Mumbai 400051, India
Interests: cultivated meat; fermentation; bioreactors; stem cells; tissue engineering

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Assistant Guest Editor
MeliBio, Inc., Berkeley, CA, USA
Interests: environmental impacts of food production; biofermentation; novel ingredients; next-generation nutrition

Special Issue Information

Dear Colleagues,

It is our pleasure to invite you to contribute a manuscript to this Special Issue on “Sensors, Devices, and Systems for Future Food Production and Packaging". The United Nations estimates that the global population will reach 9.7 billion by 2050, which will go along with increased urbanization and change in consumer preferences. The rise in caloric demand, as well as aggressive consumption of proteins, will lead to increased exploitation of natural resources, putting tremendous pressure on the environment with catastrophic consequences on climate and global warming. Hence, innovative technologies that can disrupt current means of agricultural produce to enhance productivity with minimal environmental impact are imperative. “Future Foods” is an exciting and emerging area where systems/devices/sensors developed in the fields of biomedicine, tissue engineering, diagnostics, regenerative medicine, cell therapy, etc. could be adapted for growing more, functional, and better foods. One of the major emerging areas under “Future Foods” is developing alternative proteins and components produced by cellular agriculture. Existing bioprocessing technologies are being optimized and further designed to integrate new requirements for alternative protein production. Despite the tremendous recent breakthroughs, most alternative protein categories, including cultured meat/cultivated meat, are yet to achieve their scale-up potential, which is critical to attaining price, and taste parity. Bioprocess optimization research is vital in this particular area that will bolster the scale-up of alternative proteins. Devices, systems, and sensors are the necessary elements of the bioprocess optimization and will prove crucial for the successful scale-up of the sector to industry-level production. Furthermore, sensors, devices, and systems play an essential role in other segments of the future food value chain including packaging, distribution, and storage.

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This Special Issue will highlight advances (non-exhaustive list) in the field of:

  • Systems for mammalian, avian, insect, seafood cell isolation, enrichment, expansion (bioreactors, types/modes of bioreactors, bioprocess design, microcarrier and scaffolding biomaterials, media recycling options,);
  • Systems for the plant, algal, fungal–protein extractions, processing (solubilization, precipitation, heating, extrusion, cooling, texturization,);
  • Fermenter/bioreactor design, bioprocess design, feedstock optimization;
  • Sensing devices for cultured meat, plant-based meat, insect-based meat, agriculture, vertical farming, food-borne pathogens, food quality, food ingredient quality;
  • CFD modeling—computational modelling for optimization of processes and products;
  • Food processing systems (product formulation)—3D (bio)printers, flavouring, texturization;
  • Industry 4.0—Integration of IoT (during the food manufacturing process for food safety), blockchain (tracing the lifecycle of food products), and AI (sorting food, ensuring hygiene standards, food supply optimization,);
  • Packaging—Innovative active and intelligent packaging methods/processes/systems, tracking of food ingredients/finished food products, recycling, and valorization, etc. 

Dr. Deepak Choudhury
Dr. Ivana Gadjanski
Dr. Akshay Vishnu Bhat
Mr. Darko Mandich
Guest Editors

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Keywords

  • Active and intelligent packaging
  • Alternative proteins
  • Biomaterials
  • Bioprocessing
  • Bioreactors
  • Biosensors
  • Cellular agriculture
  • CFD modelling
  • Cultured meat/cell-based meat/cultivated meat
  • Fermentation
  • Food 3D (bio)printers
  • Food scanners
  • Future foods
  • Industry 4.0
  • Microcarriers
  • Plant-based meat alternatives
  • Recycling
  • Sensors
  • Sustainable packaging
  • Texturization
  • Valorization

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Published Papers (3 papers)

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Review

20 pages, 1076 KiB  
Review
Cellular Aquaculture: Prospects and Challenges
by Mukunda Goswami, Yashwanth Belathur Shambhugowda, Arjunan Sathiyanarayanan, Nevil Pinto, Alexandrea Duscher, Reza Ovissipour, Wazir Singh Lakra and Ravishankar Chandragiri Nagarajarao
Micromachines 2022, 13(6), 828; https://doi.org/10.3390/mi13060828 - 26 May 2022
Cited by 13 | Viewed by 6539
Abstract
Aquaculture plays an important role as one of the fastest-growing food-producing sectors in global food and nutritional security. Demand for animal protein in the form of fish has been increasing tremendously. Aquaculture faces many challenges to produce quality fish for the burgeoning world [...] Read more.
Aquaculture plays an important role as one of the fastest-growing food-producing sectors in global food and nutritional security. Demand for animal protein in the form of fish has been increasing tremendously. Aquaculture faces many challenges to produce quality fish for the burgeoning world population. Cellular aquaculture can provide an alternative, climate-resilient food production system to produce quality fish. Potential applications of fish muscle cell lines in cellular aquaculture have raised the importance of developing and characterizing these cell lines. In vitro models, such as the mouse C2C12 cell line, have been extremely useful for expanding knowledge about molecular mechanisms of muscle growth and differentiation in mammals. Such studies are in an infancy stage in teleost due to the unavailability of equivalent permanent muscle cell lines, except a few fish muscle cell lines that have not yet been used for cellular aquaculture. The Prospect of cell-based aquaculture relies on the development of appropriate muscle cells, optimization of cell conditions, and mass production of cells in bioreactors. Hence, it is required to develop and characterize fish muscle cell lines along with their cryopreservation in cell line repositories and production of ideal mass cells in suitably designed bioreactors to overcome current cellular aquaculture challenges. Full article
(This article belongs to the Special Issue Sensors, Devices and Systems for Future Food Production and Packaging)
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44 pages, 1264 KiB  
Review
Bioengineering Outlook on Cultivated Meat Production
by Ivana Pajčin, Teodora Knežić, Ivana Savic Azoulay, Vanja Vlajkov, Mila Djisalov, Ljiljana Janjušević, Jovana Grahovac and Ivana Gadjanski
Micromachines 2022, 13(3), 402; https://doi.org/10.3390/mi13030402 - 28 Feb 2022
Cited by 31 | Viewed by 12349
Abstract
Cultured meat (also referred to as cultivated meat or cell-based meat)—CM—is fabricated through the process of cellular agriculture (CA), which entails application of bioengineering, i.e., tissue engineering (TE) principles to the production of food. The main TE principles include usage of cells, grown [...] Read more.
Cultured meat (also referred to as cultivated meat or cell-based meat)—CM—is fabricated through the process of cellular agriculture (CA), which entails application of bioengineering, i.e., tissue engineering (TE) principles to the production of food. The main TE principles include usage of cells, grown in a controlled environment provided by bioreactors and cultivation media supplemented with growth factors and other needed nutrients and signaling molecules, and seeded onto the immobilization elements—microcarriers and scaffolds that provide the adhesion surfaces necessary for anchor-dependent cells and offer 3D organization for multiple cell types. Theoretically, many solutions from regenerative medicine and biomedical engineering can be applied in CM-TE, i.e., CA. However, in practice, there are a number of specificities regarding fabrication of a CM product that needs to fulfill not only the majority of functional criteria of muscle and fat TE, but also has to possess the sensory and nutritional qualities of a traditional food component, i.e., the meat it aims to replace. This is the reason that bioengineering aimed at CM production needs to be regarded as a specific scientific discipline of a multidisciplinary nature, integrating principles from biomedical engineering as well as from food manufacturing, design and development, i.e., food engineering. An important requirement is also the need to use as little as possible of animal-derived components in the whole CM bioprocess. In this review, we aim to present the current knowledge on different bioengineering aspects, pertinent to different current scientific disciplines but all relevant for CM engineering, relevant for muscle TE, including different cell sources, bioreactor types, media requirements, bioprocess monitoring and kinetics and their modifications for use in CA, all in view of their potential for efficient CM bioprocess scale-up. We believe such a review will offer a good overview of different bioengineering strategies for CM production and will be useful to a range of interested stakeholders, from students just entering the CA field to experienced researchers looking for the latest innovations in the field. Full article
(This article belongs to the Special Issue Sensors, Devices and Systems for Future Food Production and Packaging)
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20 pages, 876 KiB  
Review
Systems for Muscle Cell Differentiation: From Bioengineering to Future Food
by Kah-Yin Lee, Hui-Xin Loh and Andrew C. A. Wan
Micromachines 2022, 13(1), 71; https://doi.org/10.3390/mi13010071 - 31 Dec 2021
Cited by 17 | Viewed by 7568
Abstract
In light of pressing issues, such as sustainability and climate change, future protein sources will increasingly turn from livestock to cell-based production and manufacturing activities. In the case of cell-based or cultured meat a relevant aspect would be the differentiation of muscle cells [...] Read more.
In light of pressing issues, such as sustainability and climate change, future protein sources will increasingly turn from livestock to cell-based production and manufacturing activities. In the case of cell-based or cultured meat a relevant aspect would be the differentiation of muscle cells into mature muscle tissue, as well as how the microsystems that have been developed to date can be developed for larger-scale cultures. To delve into this aspect we review previous research that has been carried out on skeletal muscle tissue engineering and how various biological and physicochemical factors, mechanical and electrical stimuli, affect muscle cell differentiation on an experimental scale. Material aspects such as the different biomaterials used and 3D vs. 2D configurations in the context of muscle cell differentiation will also be discussed. Finally, the ability to translate these systems to more scalable bioreactor configurations and eventually bring them to a commercial scale will be touched upon. Full article
(This article belongs to the Special Issue Sensors, Devices and Systems for Future Food Production and Packaging)
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