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Nutrition Strategy for Maternal and Infant Wellbeing

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutrition in Women".

Deadline for manuscript submissions: 15 April 2025 | Viewed by 1147

Special Issue Editors


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Guest Editor
Department of Obstetrics and Gynecology, ASST Santi Paolo e Carlo-San Paolo University Hospital, 20142 Milan, Italy
Interests: fetal–maternal medicine; fetal programming; prediction and management of great obstetric syndromes; placental disease; prenatal diagnosis
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Clinical Department of Pediatrics, San Paolo Hospital, ASST Santi Paolo e Carlo-San Paolo University Hospital, 20142 Milan, Italy
Interests: pediatric; dietary interventions; familial hypercholesterolemia; dyslipidemia; nutraceuticals
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

During pregnancy, eating a balanced variety and appropriate quantity of nutritious foods improves both obstetric outcomes and infant health, according to the well-established fetal programming hypothesis.

Nowadays, heterogeneity in dietary intakes, patterns, and behaviors related to socio-economic issues, cultural reasons, or changes in modern food offering represents a new challenge for specialists in fetal–maternal medicine and pediatrics. Additionally, the exposure to various environmental pollutants during pregnancy and in the early-life stages can affect both maternal health and reproductive health in children.

This upcoming Special Issue aims to present a series of articles covering dietary intake/patterns/behaviors and their relationship to undernutrition, overweight and obesity, hypertension, diabetes, metabolic syndrome, and suboptimal neurodevelopment. The main findings from these papers will provide solid evidence to underscore future policy making for nutritional improvements among populations at a childbearing age.

Dr. Stefania Triunfo
Dr. Giuseppe Banderali
Guest Editors

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Keywords

  • diet
  • nutrition
  • prevention
  • pregnancy
  • children
  • fetal programming
  • adverse outcomes
  • diabetes
  • hypertension
  • overweight
  • obesity
  • suboptimal neurodevelopment
  • metabolic diseases

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Published Papers (2 papers)

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Research

14 pages, 877 KiB  
Article
Impact of Vitamin D Deficiency on Gestational Diabetes and Pregnancy Outcomes Across Diverse Ethnic Groups: A Retrospective Cohort Study
by Sushant Saluja, Navin Sugathan, Roopa Krishnamurthy and Edward B. Jude
Nutrients 2025, 17(3), 565; https://doi.org/10.3390/nu17030565 - 2 Feb 2025
Viewed by 296
Abstract
Background: Vitamin D deficiency is linked to adverse pregnancy outcomes like gestational diabetes mellitus (GDM), but its effects across ethnic groups are unclear. This study examines the relationship among vitamin D levels, glucose tolerance, GDM prevalence, and neonatal outcomes in a multi-ethnic cohort [...] Read more.
Background: Vitamin D deficiency is linked to adverse pregnancy outcomes like gestational diabetes mellitus (GDM), but its effects across ethnic groups are unclear. This study examines the relationship among vitamin D levels, glucose tolerance, GDM prevalence, and neonatal outcomes in a multi-ethnic cohort of pregnant women. Methods: We conducted a retrospective analysis of 252 pregnant women from antenatal clinics between 2018 and 2022. Participants were divided into four groups based on serum vitamin D levels: severely deficient (<25 nmol/L), deficient (25–50 nmol/L), insufficient (51–75 nmol/L), and sufficient (>75 nmol/L). The analysis included multivariate linear regression models adjusted for age, ethnicity, BMI, gestational diabetes status, and seasonality. An area under the receiver operating characteristic (AUROC) analysis identified the vitamin D threshold linked to an increased GDM risk. Results: Women classified as severely deficient had higher fasting glucose levels (5.73 ± 1.24 mmol/L) than those in other groups (p = 0.003, adjusted). The AUROC analysis identified a vitamin D threshold of 45 nmol/L associated with an elevated GDM risk (AUROC = 0.78, CI: 0.70–0.85). South Asian women had lower vitamin D levels (41.17 ± 18.03 nmol/L vs. 45.15 ± 16.75 nmol/L) and higher glucose tolerance test (GTT) levels than Caucasian women, despite having lower BMIs. Moreover, vitamin D levels positively correlated with neonatal birth weight (p = 0.02). Conclusions: There is a strong link between vitamin D deficiency and increased GDM risk, especially among South Asian women. These findings underscore the need for targeted interventions to improve vitamin D levels in high-risk ethnic groups. Full article
(This article belongs to the Special Issue Nutrition Strategy for Maternal and Infant Wellbeing)
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13 pages, 240 KiB  
Article
Prenatal Breastfeeding Intention Is Consistently Associated with Breastfeeding Duration Among WIC-Participating Women
by Christopher E. Anderson, Fu-Chi Yang and Shannon E. Whaley
Nutrients 2024, 16(24), 4289; https://doi.org/10.3390/nu16244289 - 12 Dec 2024
Viewed by 580
Abstract
Background/Objective: The Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) provides breastfeeding support to participating women in low-income households. This study aimed to determine the relationships between prenatal maternal and household characteristics and breastfeeding duration, as well as whether these characteristics [...] Read more.
Background/Objective: The Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) provides breastfeeding support to participating women in low-income households. This study aimed to determine the relationships between prenatal maternal and household characteristics and breastfeeding duration, as well as whether these characteristics modify associations of prenatal breastfeeding intention with breastfeeding duration. Methods: This is a prospective cohort study of pregnant respondents to Los Angeles County (LAC), California, WIC surveys conducted between 2005 and 2020 (n = 1014). Associations of prenatal breastfeeding intention with duration (months) of any or fully breastfeeding, determined by WIC infant food package issuance, were assessed with linear regression models. Results: Most women reported the intention to breastfeed (67.7%) and perceived breastfeeding support during pregnancy from WIC and family/friends was associated with breastfeeding intention (both p-values < 0.0001). Stronger breastfeeding intention, lower maternal BMI, greater maternal age, greater maternal education, paternal cohabitation and employment, and greater breastfeeding support from family/friends were associated with longer duration of any or fully breastfeeding in multivariable models. Stronger breastfeeding intention was more strongly associated with longer duration of any breastfeeding among women with lower BMI (interaction p-value 0.03). Conclusions: Breastfeeding support from WIC is an important contributor to stronger breastfeeding intention. Given the robust association of breastfeeding intention with breastfeeding duration, regardless of maternal and household characteristics, WIC breastfeeding support during pregnancy represents an important mechanism to improve breastfeeding outcomes in this population. Further research is needed to understand the directionality of associations between breastfeeding support and intention among WIC participants. Full article
(This article belongs to the Special Issue Nutrition Strategy for Maternal and Infant Wellbeing)
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