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Diet and Lifestyle Factors Associated with Allergic Diseases in Early...
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Diet and Lifestyle Factors Associated with Allergic Diseases in Early Life

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutritional Immunology".

Deadline for manuscript submissions: 25 January 2025 | Viewed by 873

Special Issue Editor

Dr. Remo Frei

E-Mail Website
Guest Editor
1. Christine Kühne Center for Allergy Research and Education (CK-CARE), Davos, Switzerland
2. Division of Respiratory Medicine and Allergology, Department of Paediatrics, Inselspital, University of Bern, Bern, Switzerland
Interests: allergy; immune regulation; microbiome; metabolome; short-chain fatty acids; inflammatory response; epithelial barrier integrity

Special Issue Information

Dear Colleagues,

The prevalence of allergic diseases has increased in the past few decades in Westernized countries. Nowadays, up to 30% of children suffer from at least one allergic disease, making allergies a significant public health concern. Allergies are a complex inflammatory disease characterized by a T-helper cell-type-2-driven phenotype, as well as epidermal and immune-related genotypes, skin barrier defects, immune dysregulation and microbial dysbiosis.

Epidemiological studies have shown that lifestyle factors such as growing up on a farm or nutrition diversity in the first year of life can beneficially influence the developing gut microbiome and metabolome; both factors have been connected to healthy immune homeostasis and epithelial barrier integrity development in children.

Understanding the influences of dietary and lifestyle factors on the development of the microbiome and the immune system is crucial to reversing the increase in allergy prevalence and developing preventive strategies. Therefore, this Special Issue, titled ‘Diet and Lifestyle Factors Associated with Allergic Diseases in Early Life’, will highlight these issues in greater depth.

Dr. Remo Frei
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • allergy
  • lifestyle
  • nutrition
  • immune regulation
  • epithelial barrier function
  • microbiome
  • metabolome
  • risk factor
  • protective factor
  • early life
  • childhood

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Published Papers (1 paper)

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Research

11 pages, 263 KiB  
Article
Validation of a Food Frequency Questionnaire: VioScreen-Allergy
by Kaci Pickett-Nairne, Deborah Glueck, Jessica Thomson, Rick Weiss, Kelly N. Z. Fuller, Stefka Fabbri, Claudia Schaefer, Courtney Evans, Emily Bowhay, Monica Martinez, Wendy Moore, David Fleischer and Carina Venter
Nutrients 2024, 16(21), 3772; https://doi.org/10.3390/nu16213772 - 2 Nov 2024
Viewed by 696
Abstract
Background/Objectives: An adapted version of an online pictorial food frequency questionnaire (FFQ), VioScreen-Allergy, assesses total dietary intake and intake of allergens and foods in the maternal diet index (MDI), linked to offspring allergy. This study assessed intermethod reliability, test–retest reliability, and external validity [...] Read more.
Background/Objectives: An adapted version of an online pictorial food frequency questionnaire (FFQ), VioScreen-Allergy, assesses total dietary intake and intake of allergens and foods in the maternal diet index (MDI), linked to offspring allergy. This study assessed intermethod reliability, test–retest reliability, and external validity of the VioScreen-Allergy. Methods: Females of childbearing age were recruited at Denver Health and Children’s Hospital, Colorado, USA, and were asked to complete four 24 h recalls and two VioScreen-Allergy FFQs over the course of a month. All those with at least two 24 h dietary recalls and both VioScreen-Allergy assessments were analyzed. Energy-adjusted and non-adjusted linear mixed models (1) compared MDI scores and intake of nutrients and allergens as measures of intermethod reliability; (2) evaluated VioScreen-Allergy test–retest reliability as differences between repeated measurements; and (3) assessed external validity by modeling associations between VioScreen-Allergy-derived intake of beta-carotene and orange vegetables and Veggie Meter®-assessed skin carotenoids. Bonferroni corrections controlled multiple comparisons within the assessment. Results: Of 53 participants enrolled, 25 demographically dissimilar participants were included in the analysis. There were no significant differences between 24 h recall and VioScreen-Allergy mean intakes of macronutrients, micronutrients, allergens, or MDI, except for Vitamin C, niacin, and cashew allergen protein. There were no significant differences between repeated measurements of VioScreen-Allergy, either energy-adjusted or unadjusted. Both beta-carotene and orange vegetable servings were significantly associated with Veggie Meter®. Conclusions: Although non-significance could have been due to low power, clinical as well as statistical assessments of intermethod reliability, test–retest reliability, and external validity suggest that VioScreen-Allergy has reasonable utility for trials assessing food allergens and MDI in the context of overall intake. The VioScreen questionnaire can also be used in future studies to assess macro- and micronutrient intake. Additional validation studies assessing different portion sizes and foods eaten by infants and young children are currently undergoing. Full article
(This article belongs to the Special Issue Diet and Lifestyle Factors Associated with Allergic Diseases in Early Life)
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