Parasites and Parasitic Diseases in the Livestock Industry in Latin America

A special issue of Pathogens (ISSN 2076-0817). This special issue belongs to the section "Parasitic Pathogens".

Deadline for manuscript submissions: 20 April 2025 | Viewed by 4320

Special Issue Editor


E-Mail Website
Guest Editor
Centro Nacional de Investigación Disciplinaria en Salud Animal e Inocuidad, Jiutepec 62550, Morelos, Mexico
Interests: ecto-parasites; endo-parasites; control strategies; sustainability; ruminants
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

From the point of view of biodiversity, Latin America (LA) is a privileged region, since it contains a large variety of plants, animals, and forms of life. It is estimated that more than 40% of the world's biodiversity is situated in this area. This region accounts for around sixty percent of global terrestrial life, and diverse freshwater and marine species can be found within this region. The bio-diversity in this region where organisms share the same habitats trying to survive in the face of adverse biotic and abiotic conditions promotes the establishment of natural regulating mechanisms such as parasitism. Cattle and small ruminants are continuously exposed to external parasites, i.e., ticks (Rhipicephalus microplus), horn flies (Haematobia irritans) and stable flies(Stomoxis calcitrans), and also to internal parasitosis, including gastrointestinal parasitic nematodes, liver fluke Fasciola hepatica and protozoa, i.e., Eimeria spp. These parasitosis are responsible for important economic loses affecting the livestock industry. The problem caused by parasites to animals worsens by the lack of efficacy of anti-parasitic chemical drugs due to the development of anti-parasitic resistance (APR). The effects and consequences of parasitic diseases together with other infectious diseases on animal health and the economy of farmers demotivate them and sometimes, producers abandon their livestock activity. The present Special Issue displays research studies developed in the LA region that contribute to understanding the problem of ecto and endo parasites in cattle and small ruminants from an epidemiological perspective, including the problem of APR and sustainable methods of control and prevention of the main parasitic diseases affecting ruminants in LA.    

Topics for submissions

  • Epidemiology of ecto and endo parasitic diseases;
  • Resistance to anthelmintic chemical drugs;
  • Resistance to ixodicides;
  • Plant and plant metabolites against ecto and endo parasites;
  • Biological control of ecto and endo parasites;
  • Other sustainable alternative methods of control of ecto and endo parasitic diseases

Dr. Pedro Mendoza de Gives
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pathogens is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • parasitic diseases
  • epidemiology
  • antiparasitic resistance
  • alternative methods of control
  • livestock
  • small ruminants

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.

Further information on MDPI's Special Issue polices can be found here.

Published Papers (4 papers)

Order results
Result details
Select all
Export citation of selected articles as:

Research

11 pages, 6192 KiB  
Article
In Situ Localization of Staphylococcus shinii and Staphylococcus succinus in Infected Rhipicephalus microplus Ticks: Implications for Biocontrol Strategies
by Cesar A. Arreguin-Perez, Raquel Cossio-Bayugar, Hugo Aguilar-Diaz and Estefan Miranda-Miranda
Pathogens 2024, 13(12), 1025; https://doi.org/10.3390/pathogens13121025 - 21 Nov 2024
Viewed by 449
Abstract
Rhipicephalus microplus is a blood-sucking parasite that causes heavy infestations on cattle and is a vector for severe tick-borne diseases, such as anaplasmosis and babesiosis, and poses a significant threat to the cattle industry. Cattle ticks show increasing acaricide resistance, which creates an [...] Read more.
Rhipicephalus microplus is a blood-sucking parasite that causes heavy infestations on cattle and is a vector for severe tick-borne diseases, such as anaplasmosis and babesiosis, and poses a significant threat to the cattle industry. Cattle ticks show increasing acaricide resistance, which creates an additional problem concerning the inefficient chemical control of tick populations in cattle-grazing areas, necessitating the exploration of alternative tick biocontrol methods. Our study aimed to demonstrate the acaropathogenic efficacy of two bacterial species during experimental infections on R. microplus. Our experimental data confirmed that S. shinii and S. succinus exhibited significant acaropathogenic properties against R. microplus, as demonstrated by the tracking of fluorescent-labeled bacteria within the engorged-tick body. Our experiments revealed that both bacterial species could infect the hemolymph, salivary glands, and vestibular vagina of the tick, inducing histological changes in the affected organs that may impair feeding as well as reproductive capabilities. Gené’s organ infection was detected only in S. succinus. Our findings offer valuable insights for developing biocontrol strategies to manage Rhipicephalus microplus populations effectively. Full article
Show Figures

Figure 1

13 pages, 1262 KiB  
Article
Excreted/Secreted 15-kDa Proteins and Serine Protease Peptides from Haemonchus contortus Act as Immune-Response Enhancers in Lambs
by René Camas-Pereyra, Génesis Andrea Bautista-García, Gustavo Pérez-Anzúrez, Zaira Carolina Duran-Cortes, David Emanuel Reyes-Guerrero, Jocelyn Maza-Lopez, Agustín Olmedo-Juárez and María Eugenia López-Arellano
Pathogens 2024, 13(7), 604; https://doi.org/10.3390/pathogens13070604 - 22 Jul 2024
Viewed by 1334
Abstract
This study assessed the immunoprotective effect in lambs of a native excreted/secreted 15-kDa protein and two synthesised S28 peptides derived from the infective transitory larvae (xL3) and adult stages (AS) of Haemonchus contortus. Twenty-two Pelibuey lambs were divided into negative [...] Read more.
This study assessed the immunoprotective effect in lambs of a native excreted/secreted 15-kDa protein and two synthesised S28 peptides derived from the infective transitory larvae (xL3) and adult stages (AS) of Haemonchus contortus. Twenty-two Pelibuey lambs were divided into negative and positive control groups, as well as immunised lamb groups, with 100 µg of the 15-kDa native protein (15kDaNP) and S28 peptides (S28P). The eggs per gram (EPG) and haematocrit were measured, and AS were counted and morphologically measured. To assess the immunoprotection in lambs, indirect enzyme-linked immunosorbent assays and relative expression analyses of immune cytokines were performed using serum and abomasal samples. Our results showed a 72.28% reduction in adult worms (AW) in the 15kDaNP-immunised group, achieving a high clinical response with 41% haematocrit and low EPG values (436 ± 661). Conversely, the S28P group achieved the highest IgG levels (2.125 ± 0.880 OD), with AW exhibiting the greatest body length (p > 0.05) and upregulation of the IL5 and FCεR1A genes associated with nematode control. The 15kDaNP group showed increased expression of genes related to nematode control and anti-inflammatory responses, including IL4, IL5, IL6, and IL13 (p < 0.05). The S28P and 15kDaNP should be explored as potential vaccines against sheep haemonchosis. Full article
Show Figures

Figure 1

12 pages, 830 KiB  
Article
Understanding Artemisia cina Ethyl Acetate Extract’s Anthelmintic Effect on Haemonchus contortus Eggs and L3 Larvae: The Synergism of Peruvin Binary Mixtures
by Luis David Arango-De-la Pava, Manasés González-Cortazar, Alejandro Zamilpa, Jorge Alfredo Cuéllar-Ordaz, Héctor Alejandro de la Cruz-Cruz, Rosa Isabel Higuera-Piedrahita and Raquel López-Arellano
Pathogens 2024, 13(6), 509; https://doi.org/10.3390/pathogens13060509 - 16 Jun 2024
Cited by 1 | Viewed by 1180
Abstract
Haemonchus contortus, a blood-feeding parasite in grazing sheep, causes economic losses. Drug resistance necessitates exploring plant-based anthelmintics like Artemisia cina (Asteraceae). The plant, particularly its ethyl acetate extract, shows anthelmintic activity against H. contortus. However, there is limited information on pharmacodynamic [...] Read more.
Haemonchus contortus, a blood-feeding parasite in grazing sheep, causes economic losses. Drug resistance necessitates exploring plant-based anthelmintics like Artemisia cina (Asteraceae). The plant, particularly its ethyl acetate extract, shows anthelmintic activity against H. contortus. However, there is limited information on pharmacodynamic interactions in ethyl acetate compounds. The study aims to identify pharmacodynamic interactions in the ethyl acetate extract of A. cina with anthelmintic effects on H. contortus eggs and L3 larvae using binary mixtures. Bioactive compounds were isolated via chromatography and identified using spectroscopic techniques. Pharmacodynamic interactions were assessed through binary mixtures with a main compound. Four bioactive compounds were identified: 1-nonacosanol, hentriacontane, peruvin, and cinic acid. Binary mixtures, with peruvin as the main compound, were performed. Peruvin/1-nonacosanol-hentriacontane and peruvin/cinic acid mixtures demonstrated 1.42-fold and 4.87-fold increased lethal effects in H. contortus L3 infective larvae, respectively, at a 0.50LC25/0.50LC25 concentration. In this work, we determined the synergism between bioactive compounds isolated from the ethyl acetate extract of A. cina and identified unreported compounds for the specie. Full article
Show Figures

Figure 1

18 pages, 4633 KiB  
Article
Assessing the In Vitro Individual and Combined Effect of Arthrobotrys oligospora and A. musiformis (Orbiliales) Liquid Culture Filtrates against Infective Larvae of the Sheep Blood-Feeding Nematode Haemonchus contortus (Trichostrongylidae)
by Antonio Colinas-Picazo, Pedro Mendoza-de Gives, Gustavo Pérez-Anzúrez, Enrique Gutiérrez-Medina, Génesis Andrea Bautista-García, Edgar Jesús Delgado-Núñez and Agustín Olmedo-Juárez
Pathogens 2024, 13(6), 498; https://doi.org/10.3390/pathogens13060498 - 11 Jun 2024
Viewed by 936
Abstract
Background: Arthrobotrys species are nematophagous fungi that secrete extracellular nematocidal products (ECP). The individual and combined effects of ECP from Arthrobotrys oligospora (Ao) and A. musiformis (Am) growth in liquid media against Haemonchus contortus L3 (HcL3) were assessed. Methods: [...] Read more.
Background: Arthrobotrys species are nematophagous fungi that secrete extracellular nematocidal products (ECP). The individual and combined effects of ECP from Arthrobotrys oligospora (Ao) and A. musiformis (Am) growth in liquid media against Haemonchus contortus L3 (HcL3) were assessed. Methods: The isolation, morphological (MI) and molecular identification (Mol-I), assessment of nematocidal activity (NA) of fungal liquid culture filtrates (LCF) in two liquid media alone and in combination and the myco-compound profile identification (MCP) were performed. Results: The MI suggested that the fungi corresponded to the species Ao and Am. This result was confirmed by PCR analysis followed by sequencing, alignment and a phylogenetic analysis. Likewise, the highest Hc mortalities were 91.4% with individual LCF of Am and 86.2% with those of Ao at the highest concentration (100 mg/mL) in Czapek-Dox Broth. The combination of both LCF resulted in a similarly high larval mortality with no statistical differences in relation to individual activity (p > 0.05). The MCP showed the presence of alkaloids in both fungi. Coumarins, sterols and saponins were found only in Ao. Main conclusions: Both fungi produced ECP with a high NA that could be identified and assessed in future studies as potential natural anthelmintic compounds. Full article
Show Figures

Figure 1

Back to TopTop