Sensitivity Enhancement Approaches to the Separation Techniques for Pharmaceutical Analysis and Therapeutic Drug Monitoring
A special issue of Separations (ISSN 2297-8739). This special issue belongs to the section "Analysis of Natural Products and Pharmaceuticals".
Deadline for manuscript submissions: closed (30 September 2023) | Viewed by 10999
Special Issue Editors
Interests: automation in liquid chromatography; capillary electrophoresis; mass spectrometry; flow injection analysis; therapeutic drug monitoring; quality control of pharmaceuticals; green chemistry
Interests: HPLC; LC-MS; environmental analytical chemistry; green chemistry technology; chromatographic method development; sample preparation; quality control for analysis of drugs in dosage forms and/or in biological fluids
Special Issues, Collections and Topics in MDPI journals
Interests: HPLC; LC-MS; capillary electrophoresis; immune analytical methods and Immunosensors; quality control for analysis of drugs in dosage forms or/and in biological fluids
Special Issue Information
Dear Colleagues,
Several separation techniques are available for pharmaceutical and biomedical analysis, but when these techniques are utilized alone, where it is essential to quantify the analytes at the lowest possible concentrations, the success rates are not very encouraging. This could imply that even robust routine separation techniques that provide reliable specificity and validity at the usual working concentrations can fail at low concentration levels of pharmaceuticals. This poses significant problems for investigating product purity and drug monitoring in bio-fluid samples. Sensitivity enhancement approaches are consequently required to maximize the performance of separation procedures. This issue focuses on potential strategies for enhancing sensitivity as they can be applied to current separation techniques for pharmaceutical analysis and therapeutic drug monitoring.
Prof. Dr. Samy Emara
Prof. Dr. Randa Abdel-Salam
Prof. Dr. Ibrahim Darwish
Guest Editors
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Keywords
- pharmaceutical analysis
- biomedical analysis
- therapeutic drug monitoring
- separation techniques
- sensitivity enhancement
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