Biological Effect of Environmental Pollutants: Silkworm as a Model Organism

A special issue of Toxics (ISSN 2305-6304). This special issue belongs to the section "Novel Methods in Toxicology Research".

Deadline for manuscript submissions: 30 April 2025 | Viewed by 658

Special Issue Editor

School of Life Sciences, Jiangsu University, Zhenjiang 212013, China
Interests: multi-omics; silkworm; toxicology; biomarker

Special Issue Information

Dear Colleagues,

The biological effects of environmental pollution on silkworms are significant, mainly reflected in air pollution, pesticides, and environmental hormones. Fluoride in air pollution also causes toxicity to silkworms, and there is a fluoride tolerance mechanism in their bodies. Silkworms have a short life cycle, simple feeding, and low cost. Due to their artificial domestication, their stress resistance is gradually deteriorating, making them sensitive to adverse external factors. Therefore, they are very suitable for studying the toxicological mechanisms of environmental pollution factors. Pesticides and hormones often cause toxicity to sericulture by affecting cell apoptosis and by disrupting the antioxidant defense system. In addition, an excessive intake of heavy metals, such as arsenic, cadmium, lead, etc., from mulberry leaves can also damage the digestive system of silkworms and affect their growth and development. This type of research will not only help to elucidate the toxicological mechanisms of environmental pollution but will also present significant implications for the sustainable development of the silkworm industry.

Dr. Liang Chen
Guest Editor

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Keywords

  • silkworm
  • toxicity
  • biomarker
  • proteomics
  • metabolomics

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Published Papers (1 paper)

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Review

23 pages, 3204 KiB  
Review
Toxicity of Per- and Polyfluoroalkyl Substances and Their Substitutes to Terrestrial and Aquatic Invertebrates—A Review
by Jiaxin Zhang, Hassan Naveed, Keping Chen and Liang Chen
Toxics 2025, 13(1), 47; https://doi.org/10.3390/toxics13010047 - 9 Jan 2025
Viewed by 539
Abstract
Per- and polyfluoroalkyl substances (PFASs) have been widely used in daily life but they cause certain impacts on the environment due to their unique carbon–fluorine chemical bonds that are difficult to degrade in the environment. Toxicological studies on PFASs and their alternatives have [...] Read more.
Per- and polyfluoroalkyl substances (PFASs) have been widely used in daily life but they cause certain impacts on the environment due to their unique carbon–fluorine chemical bonds that are difficult to degrade in the environment. Toxicological studies on PFASs and their alternatives have mainly focused on vertebrates, while terrestrial and aquatic invertebrates have been studied to a lesser extent. As invertebrates at the bottom of the food chain play a crucial role in the whole ecological chain, it is necessary to investigate the toxicity of PFASs to invertebrates. In this paper, the progress of toxicological studies on PFASs and their alternatives in terrestrial and aquatic invertebrates is reviewed, and the accumulation of PFASs, their toxicity in invertebrates, as well as the neurotoxicity and toxicity to reproduction and development are summarized. This provides a reference to in-depth studies on the comprehensive assessment of the toxicity of PFASs and their alternatives, promotes further research on PFASs in invertebrates, and provides valuable recommendations for the use and regulation of alternatives to PFASs. Full article
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