The Effect of Airborne Contaminants Exposure on Early Health Damage Biomarkers: 2nd Edition

A special issue of Toxics (ISSN 2305-6304). This special issue belongs to the section "Air Pollution and Health".

Deadline for manuscript submissions: 31 January 2025 | Viewed by 830

Special Issue Editors


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Guest Editor
Department of Occupational and Environmental Health, School of Public Health, Health Science Center, Xi'an Jiaotong University, Xi’an 710061, China
Interests: air pollution; cardiovascular health; environmental epidemiology; epigenetics; mental health
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Guest Editor
School of Public Health, Guangzhou Medical University, Guangzhou 511436, China
Interests: environmental epidemiology and biostatistics; climate change; extreme weather; air pollution; public health
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Guest Editor
School of Public Health, Capital Medical University, Beijing 100069, China
Interests: air pollution and health; climate change and health; cohort study; time-series study
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
School of Public Health, Fudan University, Shanghai 200437, China
Interests: environmental health

Special Issue Information

Dear Colleagues,

Air pollution is air contamination due to various airborne contaminants that are harmful to human health and are among the leading risk factors for disease burden globally. Exposure to airborne contaminants has been linked to a series of chronic diseases, including but not limited to cardiovascular, respiratory, mental, neurological, and reproductive diseases. It has been demonstrated that airborne contaminants could enter the body through the respiratory tract and circulatory system, cause complex internal cellular responses that are followed by biological effects, and lead to adverse health outcomes. The cellular responses and biological effects lie in the early stage of health damage by airborne contaminants. They could be reflected by changes in various biomarkers related to inflammation, oxidative stress, endothelial dysfunction, coagulation, autonomic imbalance, metabolic disorder, epigenetic modifications, etc. However, current studies are mainly based on cross-sectional or panel study design, limiting the convincing causal links between air pollution and biomarkers, and heterogeneity also exists among current evidence. The Special Issue aims to publish studies investigating the early health damage biomarkers and related mechanisms for the effect of airborne contaminants, particularly those from well-designed longitudinal research. Your contribution to the Special Issue is greatly appreciated and will greatly add to the existing literature.

Prof. Dr. Shaowei Wu
Prof. Dr. Jun Yang
Prof. Dr. Shengzhi Sun
Dr. Cong Liu
Guest Editors

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Keywords

  • airborne contaminants
  • biomarkers
  • biological effects
  • cellular responses
  • chronic diseases
  • early health damage
  • mechanisms

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Published Papers (1 paper)

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Review

18 pages, 4221 KiB  
Review
Association Between Long-Term Exposure to Ambient Air Pollution and Fasting Blood Glucose: A Systematic Review and Meta-Analysis
by Tong Wu, Yang Lan, Ge Li, Kai Wang, Yu You, Jiaqi Zhu, Lihua Ren and Shaowei Wu
Toxics 2024, 12(11), 792; https://doi.org/10.3390/toxics12110792 - 30 Oct 2024
Viewed by 649
Abstract
Increasing studies are indicating a potential association between ambient air pollution exposure and fasting blood glucose (FBG), an indicator of prediabetes and diabetes. However, there is inconsistency within the existing literature. The aim of this study was to summarize the associations of exposures [...] Read more.
Increasing studies are indicating a potential association between ambient air pollution exposure and fasting blood glucose (FBG), an indicator of prediabetes and diabetes. However, there is inconsistency within the existing literature. The aim of this study was to summarize the associations of exposures to particulate matters (PMs) (with aerodynamic diameters of ≤1 μm (PM1), ≤2.5 μm (PM2.5), and ≤10 μm (PM10), respectively) and gaseous pollutants (sulfur dioxide (SO2), nitrogen dioxide (NO2) and ozone (O3)) with FBG based on the existing epidemiological research for a better understanding of the relationship between air pollution and diabetes. Up to 2 July 2024, we performed a comprehensive literature retrieval from various electronic databases (PubMed, Web of Science, Scopus, and Embase). Random-effect and fixed-effect models were utilized to estimate the pooled percent changes (%) and 95% confidence intervals (CIs). Then, subgroup meta-analyses and meta-regression analyses were applied to recognize the sources of heterogeneity. There were 33 studies eligible for the meta-analysis. The results showed that for each 10 μg/m3 increase in long-term exposures to PM1, PM2.5, PM10, and SO2, the pooled percent changes in FBG were 2.24% (95% CI: 0.54%, 3.96%), 1.72% (95% CI: 0.93%, 2.25%), 1.19% (95% CI: 0.41%, 1.97%), and 0.52% (95% CI:0.40%, 0.63%), respectively. Long-term exposures to ambient NO2 and O3 were not related to alterations in FBG. In conclusion, our findings support that long-term exposures to PMs of various aerodynamic diameters and SO2 are associated with significantly elevated FBG levels. Full article
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