Association between Ambient Fine Particulate Matter Exposures and Human Health Risk

A special issue of Toxics (ISSN 2305-6304). This special issue belongs to the section "Air Pollution and Health".

Deadline for manuscript submissions: closed (30 September 2024) | Viewed by 2413

Special Issue Editors


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Guest Editor
School of Public Health, Capital Medical University, Beijing 100069, China
Interests: air pollution and health; climate change and health; cohort study; time-series study
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310000, China
Interests: environmental toxicology; air pollution; ambient fine particulate matter exposures

Special Issue Information

Dear Colleagues,

Air pollutants pose a significant risk to human health, and almost the entire global population breathes air that exceeds WHO air quality limits. Ambient fine particulate matter is among the most hazardous of all air pollutants. Daily exposure to ambient fine particulate matter has been linked to an increased risk of mortality, yet our understanding of its effects on morbidity, potential biological mechanisms, and the susceptible population remains limited.

This Special Issue of Toxics is devoted to emerging research on the adverse effects of ambient fine particulate matter exposure on health risk. Topics that will be covered include, but are not limited to, diseases of the respiratory system, the circulatory system, and the responses of other systems to particulate matter; an examination of interaction effects between ambient fine particulate matter and other air pollutants or meteorological factors, etc.; an estimation of the causal effects of ambient fine particulate matter and health; an exploration of disease mechanisms using multi-omics analysis such as transcriptomics and metagenomics; and exposure risk assessment in human populations.

We welcome contributions that shed light on these critical areas, providing insights that can inform policy, guide interventions, and ultimately protect public health against air pollution.

Prof. Dr. Shengzhi Sun
Dr. Mingluan Xing
Guest Editors

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Keywords

  • environmental toxicology
  • air pollution
  • ambient fine particulate matter exposures
  • exposure risk assessment
  • mechanisms of environmental diseases

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Published Papers (2 papers)

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Research

14 pages, 1676 KiB  
Article
Association of Air Quality Improvement and Frailty Progression: A National Study across China
by Mingqin Liu, Mohammed Zeeshan, Tiantian Sun, Xiangming Hu, Zhiqiang Nie, Haojian Dong, Guanghui Dong and Yanqiu Ou
Toxics 2024, 12(7), 464; https://doi.org/10.3390/toxics12070464 - 27 Jun 2024
Viewed by 1125
Abstract
Accumulating evidence strongly suggests that exposure to ambient air pollution is linked with increased frailty. However, little is known about the effect of improved air quality on frailty progression. We aimed to investigate whether improvements in air quality (PM1, PM2.5 [...] Read more.
Accumulating evidence strongly suggests that exposure to ambient air pollution is linked with increased frailty. However, little is known about the effect of improved air quality on frailty progression. We aimed to investigate whether improvements in air quality (PM1, PM2.5, PM10, NO2, and O3) can alleviate frailty progression, particularly in the aftermath of implementation of the “Clean Air Action” policy in China. The study involved 12,891 participants with geocoded environmental data from the nationwide China Health and Retirement Longitudinal Study (CHARLS) during the period from May 2011 to August 2015. Multivariate logistic regression models were used to analyze the association of air pollution improvements and frailty progression. The protective effects were noted for PM1, PM2.5, PM10, and NO2 indices, with an aOR (adjusted odds ratio) ranging from 0.72 to 0.79. Air quality improvement in PM1, PM2.5, PM10, and NO2 could alleviate the progression of frailty. The study is the first to examine the association between the improvement of air quality and the progression of frailty, setting a precedent for the importance of a nationwide clean air policy and its impact on healthy ageing. Full article
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15 pages, 1820 KiB  
Article
The Association between Short-Term Exposure to PM1 and Daily Hospital Admission and Related Expenditures in Beijing
by Jingwen Xu, Yan Chen, Feng Lu, Lili Chen and Zhaomin Dong
Toxics 2024, 12(6), 393; https://doi.org/10.3390/toxics12060393 - 28 May 2024
Viewed by 893
Abstract
Ambient particulate matter (PM) pollution is a leading environmental health threat worldwide. PM with an aerodynamic diameter ≤ 1.0 μm, also known as PM1, has been implicated in the morbidity and mortality of several cardiorespiratory and cerebrovascular diseases. However, previous studies [...] Read more.
Ambient particulate matter (PM) pollution is a leading environmental health threat worldwide. PM with an aerodynamic diameter ≤ 1.0 μm, also known as PM1, has been implicated in the morbidity and mortality of several cardiorespiratory and cerebrovascular diseases. However, previous studies have mostly focused on analyzing fine PM (PM2.5) associated with disease metrics, such as emergency department visits and mortality, rather than ultrafine PM, including PM1. This study aimed to evaluate the association between short-term PM1 exposure and hospital admissions (HAs) for all-cause diseases, chronic obstructive pulmonary disease (COPD), and respiratory infections (RIs), as well as the associated expenditures, using Beijing as a case study. Here, based on air pollution and hospital admission data in Beijing from 2015 to 2017, we performed a time-series analysis and meta-analysis. It was found that a 10 μg/m3 increase in the PM1 concentration significantly increased all-cause disease HAs by 0.07% (95% Confidence Interval (CI): [0, 0.14%]) in Beijing between 2015 and 2017, while the COPD and RI-related HAs were not significantly associated with short-term PM1 exposure. Meanwhile, we estimated the attributable number of HAs and hospital expenditures related to all-cause diseases. This study revealed that an average of 6644 (95% CI: [351, 12,917]) cases of HAs were attributable to ambient PM1, which was estimated to be associated with a 106 million CNY increase in hospital expenditure annually (95% CI: [5.6, 207]), accounting for 0.32% (95% CI: [0.02, 0.62%]) of the annual total expenses. The findings reported here highlight the underlying impact of ambient PM pollution on health risks and economic burden to society and indicate the need for further policy actions on public health. Full article
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