Early Life Exposure to Persistent Organic Pollutants, a Particularly Sensitive Period
A special issue of Toxics (ISSN 2305-6304). This special issue belongs to the section "Reproductive and Developmental Toxicity".
Deadline for manuscript submissions: closed (15 November 2022) | Viewed by 19021
Special Issue Editors
2. CALBINOTOX, Faculté des Sciences et Technologies, Université de Lorraine, Campus Aiguillettes BP70239, 54506 Nancy, France
Interests: environmental toxicology; Persistent Organic Pollutants (POPs); Polycyclic Aromatic Hydrocarbons (PAH); neuro-developmental disorders; biomarkers
Interests: behavioural epigenetics; molecular consequences of early life adversity; DNA methylation; HPA axis; glucocorticoid receptor; genetics and epigenetics of the stress response
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Special Issue Information
Dear Colleagues,
Accumulating evidence suggests that exposure to persistent organic pollutants (POP) during critical periods of development may be a major risk factor in the occurrence of chronic diseases later in life. An increase in the incidence of asthma, cancer, birth defects and developmental and neurodevelopmental disabilities has been pointed out in children over the last two decades. For some of these diseases, an environmental origin has been clearly established; for others, it is still at the level of assumption. This underlines the importance of the mode and period of exposure as a critical window for development and suggests that epigenetic modifications may play a key role in the onset of these disorders. The toxicity of early exposure to low levels of POP remains, therefore, to be elucidated and needs to be studied further, especially regarding the long-term effects of such cocktail exposure and its role in the incidence of disease later in life. In this context, we are pleased to invite you to participate in this Special Issue, which aims to assess the impact of POP exposure across the developmental period on the occurrence of later life phenotypes.
In this Special Issue, original research articles and reviews are welcome. Research areas may include (but are not limited to) the following:
- Environmental medicine and public health
- Environmental epidemiology
- Health risk assessment
- Early developmental toxicity
- Neurodevelopmental toxicity
- Neurodevelopmental disorders
- Endocrine disruptions
- Immune toxicity
- Immune-aging
- DOHAD (Developmental Origins of Health and Disease).
We look forward to receiving your contributions.
Dr. Nathalie Grova
Dr. Jonathan Turne
Guest Editors
Manuscript Submission Information
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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Toxics is an international peer-reviewed open access monthly journal published by MDPI.
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Keywords
- early life adversity
- perinatal exposure
- persistent organic pollutants
- DOHAD
- environmental epidemiology
- epigenetics
- neurodevelopmental toxicity
- overall life trajectories
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