Synthetic Compounds: Antioxidant and Anti-Inflammatory Activities, Biomedical Properties and Formulations
A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Health Outcomes of Antioxidants and Oxidative Stress".
Deadline for manuscript submissions: 15 April 2025 | Viewed by 752
Special Issue Editors
Interests: natural compounds; medicinal chemistry; food chemistry; antioxidants; antimicrobials; anti-inflammatory; anticancer; extracion; bioactive compounds; nutrceutical; well-being; food supplement; functional food
Special Issues, Collections and Topics in MDPI journals
Interests: chemical modification of natural compounds; medicinal chemistry; food chemistry; antioxidants; antimicrobials; anti-inflammatory; anticancer; guanidines; organic synthesis; delivery systems; drug resistance
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Whether of natural or synthetic origin, antioxidants can protect cells and tissues from free-radical-mediated damage. Antioxidants can minimize food loss, act as preservatives in drug and herbal formulations, or act as health-promoting compounds. Indeed, oxidation and inflammation are strictly connected by means of pleiotropic and redundant pathways. Antioxidants can tackle inflammation-related diseases by limiting excessive cytokine-mediated inflammatory responses. In this Special Issue, we will focus on antioxidant design, synthesis, purification, characterization, mechanisms of action, and biological and toxicological activities through in vitro, ex vivo, and in vivo investigations into synthetic antioxidants and anti-inflammatory agents. Nanotechnology-based formulations and delivery systems for these compounds, to improve bioavailability and reduce toxicity or chemical instability, will be also considered. Finally, updates on pharmacological effects, therapeutic properties, and future options in these compounds are also welcome. New protocols to assess the efficacy of these compounds will, furthermore, be considered.
The Special Issue welcomes manuscripts (reviews or research articles) regarding any aspect of synthetic antioxidants in relation to their applications in nutrition, medicinal chemistry, pharmacology and pharmacy, and food chemistry and technology.
Dr. Simone Carradori
Guest Editor
Dr. Ilaria D'Agostino
Guest Editor Assistant
Manuscript Submission Information
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Keywords
- antioxidants
- inflammation pathways
- therapeutic activity
- redox potential
- synthesis
- preclinical studies
- macrophages
- immunomodulation
- packaging
- formulations
- topical application
- polymers
- nanotechnology
- cytotoxicity
- mechanism of action
- food
- drug design
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