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Biosensors
Special Issues
Biosensing Based on Electrochemical Analysis
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Biosensing Based on Electrochemical Analysis

A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Biosensors and Healthcare".

Deadline for manuscript submissions: closed (30 April 2024) | Viewed by 8213

Special Issue Editor

Dr. Hafsa Korri-Youssoufi

E-Mail Website
Guest Editor
Institut de Chimie Moléculaire et des Matériaux d’Orsay (ICMMO), Centre National de la Recherche Scientifique, Unité Mixte de Recherche 8182, Université Paris Saclay, 17 Avenue des Sciences, 91400 Orsay, France
Interests: biosensor; biochips; electrochemistry; material chemistry; analytical chemistry; nanotechnology
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Regarding an increasing demand to develop methods and systems that enable the detection of various biomarkers of interest at ultra-trace and with high accuracy and precision, biosensor systems are analytical devices that could respond to these requirements. Biosensor devices involve biological elements that can detect the analyte and a transducer that allows for obtaining the signal. Electrochemical biosensor devices are promising analytical tools because they can convert chemical or biological reactions into electrical signals and exploit the current developments in nanotechnology and nanosciences to achieve sensitive and selective devices. Electrochemical biosensors are involved in the detection of contaminants, pathogens, and hazardous molecules and open the way to their application for human health, such as diagnosis, biomedical, environmental control, food safety, security and defense, etc.

Recent developments in biosensors based on Electrochemical analysis demonstrated their integration in point-of-care devices, Internet of Things (IoT) and wearables devices, opening the way to their implementation in various applications.

We invite authors to submit original research or review articles on novel systems or approaches in electrochemical biosensors. Potential topics include, but are not limited to:

  • Innovative concepts in electrochemical biosensors involving bioreceptors such as DNA, RNA, Aptamer protein, antibodies, carbohydrates, cell, etc.
  • New materials and nanomaterials used in electrochemical biosensor devices: carbon nanotubes, graphene, organic and inorganic nanoparticles, metal chalcogenides organic-based semiconductors, conducting polymers, bio-sourced polymers, etc.
  • Electrochemical detection analysis in vitro and in vivo.
  • Devices and systems including electrochemical biosensors such as microfluidics, wireless, IOT, etc.
  • Achievement in intelligence artificial in connection of electrochemical biosensors. 

Dr. Hafsa Korri-Youssoufi
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biosensors is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • electrochemical
  • biosensors
  • bioreceptors
  • nanomaterials
  • applications
  • IOT
  • wireless

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Published Papers (3 papers)

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Research

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12 pages, 2620 KiB  
Article
Electrochemical Characterization of Neurotransmitters in a Single Submicron Droplet
by Heekyung Park and Jun Hui Park
Biosensors 2024, 14(2), 102; https://doi.org/10.3390/bios14020102 - 17 Feb 2024
Viewed by 1676
Abstract
Single-entity electrochemistry, which employs electrolysis during the collision of single particles on ultramicroelectrodes, has witnessed significant advancements in recent years, enabling the observation and characterization of individual particles. Information on a single aqueous droplet (e.g., size) can also be studied based on the [...] Read more.
Single-entity electrochemistry, which employs electrolysis during the collision of single particles on ultramicroelectrodes, has witnessed significant advancements in recent years, enabling the observation and characterization of individual particles. Information on a single aqueous droplet (e.g., size) can also be studied based on the redox species contained therein. Dopamine, a redox-active neurotransmitter, is usually present in intracellular vesicles. Similarly, in the current study, the electrochemical properties of neurotransmitters in submicron droplets were investigated. Because dopamine oxidation is accompanied by proton transfer, unique electrochemical properties of dopamine were observed in the droplet. We also investigated the electrochemical properties of the adsorbed droplets containing DA and the detection of oxidized dopamine by the recollision phenomenon. Full article
(This article belongs to the Special Issue Biosensing Based on Electrochemical Analysis)
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12 pages, 4279 KiB  
Article
A Recognition-Molecule-Free Photoelectrochemical Sensor Based on Ti3C2/TiO2 Heterostructure for Monitoring of Dopamine
by Zhifang Wu, Fangjie Han, Tianqi Wang, Liwei Guan, Zhishan Liang, Dongxue Han and Li Niu
Biosensors 2023, 13(5), 526; https://doi.org/10.3390/bios13050526 - 7 May 2023
Cited by 3 | Viewed by 2078
Abstract
Herein, a novel, recognition-molecule-free electrode based on Ti3C2/TiO2 composites was synthesized using Ti3C2 as the Ti source and TiO2 in situ formed by oxidation on the Ti3C2 surface for the selective [...] Read more.
Herein, a novel, recognition-molecule-free electrode based on Ti3C2/TiO2 composites was synthesized using Ti3C2 as the Ti source and TiO2 in situ formed by oxidation on the Ti3C2 surface for the selective detection of dopamine (DA). The TiO2 in situ formed by oxidation on the Ti3C2 surface not only increased the catalytically active surface for DA binding but also accelerated the carrier transfer due to the coupling between TiO2 and Ti3C2, resulting in a better photoelectric response than pure TiO2. Through a series of experimental conditions optimization, the photocurrent signals obtained by the MT100 electrode were proportional to the DA concentration from 0.125 to 400 µM, with a detection limit estimated at 0.045 µM. We also monitored DA in human blood serum samples using the MT100 electrode. The results showed good recovery, demonstrating the promising use of the sensor for the analysis of DA in real samples. Full article
(This article belongs to the Special Issue Biosensing Based on Electrochemical Analysis)
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Review

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17 pages, 9023 KiB  
Review
Surface-Activated Pencil Graphite Electrode for Dopamine Sensor Applications: A Critical Review
by Sakthivel Srinivas and Annamalai Senthil Kumar
Biosensors 2023, 13(3), 353; https://doi.org/10.3390/bios13030353 - 6 Mar 2023
Cited by 9 | Viewed by 3814
Abstract
Pencil graphite electrode (PGE) is an alternative, commercially available, ready-to-use, screen-printed electrode for a wide range of electroanalytical applications. Due to the complex-matrix composition and unpredictable electro-inactive nature of PGE in its native form, a surface pre-treatment/activation procedure is highly preferred for using [...] Read more.
Pencil graphite electrode (PGE) is an alternative, commercially available, ready-to-use, screen-printed electrode for a wide range of electroanalytical applications. Due to the complex-matrix composition and unpredictable electro-inactive nature of PGE in its native form, a surface pre-treatment/activation procedure is highly preferred for using it as an electroactive working electrode for electroanalytical applications. In this article, we review various surface pre-treatment and modification procedures adopted in the literature with respect to the sensitive and selective detection of dopamine as a model system. Specific generation of the carbon–oxygen functional group, along with partial surface exfoliation of PGE, has been referred to as a key step for the activation. Based on the Scopus® index, the literature collection was searched with the keywords “pencil and dopamine”. The obtained data were segregated into three main headings as: (i) electrochemically pre-treated PGE; (ii) polymer-modified PGEs; and (iii) metal and metal nanocomposite-modified PGE. This critical review covers various surface activation procedures adopted for the activation for PGE suitable for dopamine electroanalytical application. Full article
(This article belongs to the Special Issue Biosensing Based on Electrochemical Analysis)
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