Molecular Research of Epidermal Stem Cells 2015
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".
Deadline for manuscript submissions: closed (30 September 2015) | Viewed by 94326
Special Issue Editor
Interests: molecular biology and genetics of human keratin genes; transcriptional profiling of skin cells using DNA microarrays; effects of UV light on skin; signal transduction in skin during inflammatory and proliferative processes; epidermal stem cells and differentiation
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Special Issue Information
Dear Colleagues,
Arguably among the most exciting research areas, stem cell biology recently burst out with extraordinary thrill and promise. Because of its accessibility, epidermis was among the first organs targeted by stem cell researchers. Several crucial discoveries relating to stem cells biology originated in skin research, the origins of cancers, the influence of the niche, role in wound healing and use in gene replacement therapy, to name a few. The field is fast-moving, but sufficiently mature to warrant a special inclusive and comprehensive overview to define its range, challenges and future directions.
The goal of this special issue is to provide a summary of the field, describe its impact as well as introduce the recent advances in the Molecular Research of Epidermal Stem Cells. Both keratinocyte and melanocyte stem cells will be addressed, mainly those in the hair follicles, but the extrafollicular ones as well. This issue will address the markers of epidermal stem cells, the role of the niche, the regulatory processes governing quiescence and emergence into proliferation, epigenetics, interface of stem cells with cancer and wound healing, and their use in treating dermatologic disorders.
Dr. Miroslav Blumenberg
Guest Editor
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Keywords
- bulge region
- cancer
- epidermis
- epigenetics
- gene replacement therapy
- hair
- ichthyosis
- melanocyte
- niche
- sebaceous gland
- skin
- wound healing
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