Natural Chemotherapeutic Compounds for Prevention and Treatment of Breast Cancer
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: closed (15 November 2021) | Viewed by 5895
Special Issue Editor
Interests: natural product; therapeutics; health promotion; nutraceuticals; metabolomics; medicinal chemistry; innovative technology (artificial intelligence and machine learning)
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Breast cancer is the most diagnosed type of cancer in women, and it has the second highest mortality rate in this group, following only lung cancer. Every year, an estimated 1–1.3 million breast cancer cases are diagnosed worldwide. Of these, approximately 15–20% of breast cancers in women are triple-negative breast cancer (TNBC), which is considered to be more aggressive and is often diagnosed in patients younger than 50 years old. Other types of breast cancer are more commonly diagnosed in people aged 60 or older. In addition to young women, TNBC disproportionately affects women of African and Hispanic descent than women of Caucasian descent. Asian women and non-Hispanic white women are less likely to be diagnosed with this type of cancer. Family history is a well-recognized and established risk factor for aggressive breast cancer. For example, about 70% of breast cancers diagnosed in people with an inherited BRCA mutation, particularly BRCA1, are triple-negative breast cancer. Other factors, such as environmental exposure to mixtures of chemicals, have been linked to an increased incidence of breast cancer in the United States and, in particular, among minority populations. Although family history (hereditary) risk factors associated with breast cancer are not modifiable, lifestyle and some environmental factors can be modified and prevented. A healthy lifestyle can be achieved by keeping a normal body weight, eating well or consuming a high amount of vegetables and fruit, lowering blood pressure, managing stress, maintaining enough physical activity, minimizing alcohol intake, quitting cigarette smoking, and reducing second-hand smoke exposure.
National Cancer Institute (NCI)-supported research has indicated that aggressive breast tumors are more common in younger African American and Hispanic women living in low socioeconomic status areas. This more aggressive form of breast cancer is less responsive to standard cancer treatments and is associated with a lower survival rate. The treatment of aggressive breast cancer remains a critical challenge in the medical community, because there are no targeted therapies and the prognosis remains modest. Moreover, there is an urgent need for the discovery and development of agent(s) efficacious to treat aggressive breast cancer. Studies have shown that there are alternative treatments to conventional drugs that might be effective in the management of TNBC. The peer-reviewed articles published in this Special Issue will highlight the use of natural chemotherapeutic compounds for the prevention and/or treatment of breast cancer. In addition, this Special Issue will address the issues of preventive measures for breast cancer.
Dr. Clement G. Yedjou
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- breast cancer
- conventional therapy
- traditional medicine
- natural product
- prevention
- treatment
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue polices can be found here.
