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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in Tea Tree Metabolism and Genetics
edited by Xiaoling Sun
submission deadline 20 Aug 2025 | 3 articles | Viewed by 2703 | Submission Open
Keywords: tea tree; secondary metabolite; genetic transformation; genetic breeding; tea germplasm improvement
(This special issue belongs to the Section Molecular Plant Sciences)
Functional Genomics in Translational Medicine
edited by , Oana Zanoaga and
submission deadline 20 Aug 2025 | 2 articles | Viewed by 2408 | Submission Open
Keywords: functional genomics; omics approaches; drug response/resistance; therapeutic targets; genomics and transcriptomic alteration; bioinformatic analysis; data integration; human disease; personalized medicine
(This special issue belongs to the Section Molecular Genetics and Genomics)
Advances in Computational Biology: Molecular Dynamics Simulation of Biomolecules submission deadline 20 Aug 2025 | 1 articles | Viewed by 2263 | Submission Open
Keywords: computational biology; molecular dynamics; molecular simulation of rare diseases; computational design of antimicrobials; computational design of antivirals; molecular simulation of cancer-related processes; computational design of anti-cancer molecules; molecular simulation of biotechnology processes
(This special issue belongs to the Section Molecular Informatics)
Myocardial Disease: Molecular Pathology and Treatments
edited by
submission deadline 20 Aug 2025 | 2 articles | Viewed by 2092 | Submission Open
Keywords: hypertrophic cardiomyopathy; dilated cardiomyopathy; arrhythmogenic right ventricular cardiomyopathy; amyloidosis; myocarditis; sarcoidosis; genetic abnormalities; immune mechanisms
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Natural Products in Obesity: Novel Strategies and Molecular Mechanisms: 2nd Edition
edited by
submission deadline 20 Aug 2025 | 1 articles | Viewed by 1982 | Submission Open
Keywords: obesity; inflammation; white adipose tissue; adipogenesis; oxidative stress; metabolic disease; molecular mechanisms
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Bacteriophage: Molecular Ecology and Pharmacology, 2nd Edition
edited by , and Richard Allen White III
submission deadline 20 Aug 2025 | 2 articles | Viewed by 1951 | Submission Open
Keywords: bacteriophage ecology; bacteriophage pharmacology; intercell communication of bacteria; phage-host interactions; phage-host recognition; phage receptors; phage therapy
(This special issue belongs to the Section Molecular Microbiology)
Redox Enzymes of Bacteria and Parasites as Potential Drug Targets submission deadline 20 Aug 2025 | 1 articles | Viewed by 1541 | Submission Open
Keywords: bacteria and parasite electron transport chains; membrane and cell wall component synthesis; dioxygenases; nitroreductases; antibacterial and antiparasitic agents
(This special issue belongs to the Section Biochemistry)
Advances in Pro-inflammatory and Anti-inflammatory Cytokines
edited by
submission deadline 20 Aug 2025 | 1 articles | Viewed by 1411 | Submission Open
Keywords: pro-inflammation cytokine; anti-inflammation cytokine; chemotherapy; radiotherapy; signal transduction; microbiome– host response; sepsis; bone marrow; GI; brain
(This special issue belongs to the Section Molecular Immunology)
New Molecular Perspectives in Crustacean Neuroendocrinology
edited by
submission deadline 20 Aug 2025 | 1 articles | Viewed by 1266 | Submission Open
Keywords: neuroendocrinology; neuropeptides; functional genomics; arthropods development and reproduction; crustacean aquaculture
(This special issue belongs to the Section Molecular Biology)
Design, Synthesis and Applications of the Task-Specific Molecules
edited by and
submission deadline 20 Aug 2025 | 2 articles | Viewed by 1231 | Submission Open
Keywords: task-specific molecules; molecular design and synthesis; physical/chemical absorption; catalysis (including electrocatalysis; photocatalysis; etc.); mechanism on the molecular level; molecular dynamic simulations; optical materials; optoelectronic devices; photoelectric detection; semiconductors
(This special issue belongs to the Section Physical Chemistry and Chemical Physics)
Towards Complex Molecular Cancer Therapies
edited by Luba Hunáková
submission deadline 20 Aug 2025 | 1 articles | Viewed by 1153 | Submission Open
Keywords: precision medicine; immune system harnessing; targeted therapies
(This special issue belongs to the Section Molecular Oncology)
Cutting-Edge Molecular Research in Autoimmunity
edited by
submission deadline 20 Aug 2025 | 1 articles | Viewed by 1059 | Submission Open
Keywords: autoimmunity; autoimmune diseases; multiple sclerosis; rheumatoid arthritis; lupus; type 1 diabetes; inflammatory bowel disease; biomarkers; immune cells; signaling molecules
(This special issue belongs to the Section Molecular Immunology)
Amyloid Hetero-Aggregation: 2nd Edition submission deadline 20 Aug 2025 | Viewed by 895 | Submission Open
Keywords: amyloid; co-aggregation; hetero-aggregation; human proteins; bacterial amyloids; viral proteins; cytotoxicity; structure; function
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Mechanism of Acute Myeloid Leukemia
edited by
submission deadline 20 Aug 2025 | 1 articles | Viewed by 829 | Submission Open
Keywords: leukemia; cytokine; signal transduction; apoptosis; immune therapy
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular and Cellular Research on the Glioma and Tumor Microenvironment submission deadline 20 Aug 2025 | Viewed by 786 | Submission Open
Keywords: tumour microenvironment; immune cells; cell siganling; tumor niche; tumor heterogeneity; TMZ resistance; new therapeutic strategies; endothelial cells; fibroblasts; extracellular matrix
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Insights and Design Strategies for Carbonaceous Nanomaterials submission deadline 20 Aug 2025 | Viewed by 471 | Submission Open
Keywords: carbon nanomaterials; carbon (nano)fillers; graphene; carbon nanotubes; carbon quantum dots; nanoparticles; nanostructures
(This special issue belongs to the Section Molecular Nanoscience)
Mechanistic and Small Molecule Discoveries for Therapeutic Advances in Hypertrophic and Dilated Cardiomyopathies
edited by Osha Roopnarine
submission deadline 20 Aug 2025 | Viewed by 395 | Submission Open
Keywords: hypertrophic cardiomyopathy; dilated cardiomyopathies; cardiomyopathies
(This special issue belongs to the Section Molecular Pharmacology)
Research on Luminescent Materials and Their Luminescence Mechanism submission deadline 20 Aug 2025 | Viewed by 393 | Submission Open
Keywords: luminescence; molecular/ionic level; mechanism
(This special issue belongs to the Section Materials Science)
Interfaces for the Impact of Magnetic Pulses or EMF in Molecular Biology
edited by Richard H. W. Funk
submission deadline 20 Aug 2025 | Viewed by 331 | Submission Open
Keywords: electromagnetic treatment; magnetic pulses; biological interface; cell biology; molecular biology; signaling cascades; clinical treatment; monitoring; sensors
(This special issue belongs to the Section Molecular Biophysics)
Mechanisms of Protein–Ligand Interactions in Therapies for Lifestyle Diseases and Their Complications
edited by Agnieszka Szkudlarek
submission deadline 20 Aug 2025 | Viewed by 322 | Submission Open
Keywords: chronic diseases and their complications; protein– ligand interactions; protein modifications; therapeutic efficacy; binding affinity; serum proteins; pharmaceutical applications; biomedical research
(This special issue belongs to the Section Molecular Biology)
Roles of Phytochemicals in Cancer Prevention and Therapeutics: 2nd Edition submission deadline 20 Aug 2025 | Viewed by 308 | Submission Open
Keywords: phytochemicals; cancer prevention; cancer therapeutics; oxidative stress; inflammation; energetic metabolism
(This special issue belongs to the Section Bioactives and Nutraceuticals)
New Insights into Embryonic Development
edited by
submission deadline 20 Aug 2025 | Viewed by 308 | Submission Open
Keywords: embryonic development; molecular mechanisms; cellular mechanisms; model embryos; genetic
(This special issue belongs to the Section Molecular Biology)
Microbial Resistance Mechanisms in Biotechnology: From Extremes to Applications
edited by Giovanni Gallo and
submission deadline 20 Aug 2025 | Viewed by 291 | Submission Open
Keywords: microorganism resistance systems; extreme environments; molecular adaptation; genetic pathways; biotechnological applications; industrial biotechnology; environmental remediation; extremophiles; stress tolerance; evolutionary adaptations
(This special issue belongs to the Section Molecular Microbiology)
Cellular Senescence as a Therapeutic Target in Cancer: Mechanisms, Challenges, and Therapeutic Opportunities
edited by
submission deadline 20 Aug 2025 | Viewed by 289 | Submission Open
Keywords: cellular senescence; cancer therapy; therapeutic targeting; senolytic drugs; senescence-associated secretory phenotype (SASP)
(This special issue belongs to the Section Molecular Oncology)
Solanaceae Biology: From Genetics to Metabolism
edited by
submission deadline 20 Aug 2025 | Viewed by 287 | Submission Open
Keywords: Solanaceae; nightshade family; tomato; potato; tobacco; eggplant; genetics; metabolism; crop improvement; specialized metabolite
(This special issue belongs to the Section Molecular Plant Sciences)
Exploring the Impact of the Biological Clock on Health and Disease
edited by
submission deadline 20 Aug 2025 | Viewed by 278 | Submission Open
Keywords: circadian rhythm; inflammation; oxidative stress; energy balance; metabolic syndrome; ageing; cancer; diabetes; obesity; entrainment; synchrony; melatonin
(This special issue belongs to the Section Molecular Biology)
Cell Organelle Stress Responses and Implications in Human Diseases
edited by
submission deadline 20 Aug 2025 | Viewed by 254 | Submission Open
Keywords: organelle stresses; mitochondria; ER; lysosome; human diseases
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
The Role of Cannabinoids in Human Health and Disorder
edited by and Beatrice Polini
submission deadline 20 Aug 2025 | Viewed by 252 | Submission Open
Keywords: cannabinoids; cannabinoid receptors; endocannabinoid system; ECS synthetic modulators; clinical trials
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Advancements and Applications of Phyto-Nanotherapy in Targeted Disease Treatment submission deadline 20 Aug 2025 | Viewed by 243 | Submission Open
Keywords: phyto-nanotherapy; medicinal plants; nanoparticles; targeted drug delivery; phytochemicals; phytotherapy; green nanotechnology; chronic diseases; infectious diseases
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Nanotechnology in Drug Delivery: Applications and Perspectives
edited by Ádám Juhász
submission deadline 20 Aug 2025 | Viewed by 237 | Submission Open
Keywords: nanostructured materials; drug delivery; drug– carrier interactions; hydrogel; aerogels; associated colloids; surfactants; macromolecules; blood– brain barrier; controlled release
(This special issue belongs to the Section Molecular Nanoscience)
Insights into Neurological and Psychiatric Diseases from Invertebrate Models submission deadline 20 Aug 2025 | Viewed by 222 | Submission Open
Keywords: disease model development; disease model validation; GWAS validation; ameliorative approaches; pharmacogenetics; pharmacoproteomics; disease mechanisms; suppressor/enhancer genetic screens; synthetic lethality screens; biomarker screens and validation
(This special issue belongs to the Section Molecular Neurobiology)
Cellular and Molecular Mechanisms of Cardiovascular Repair
edited by
submission deadline 20 Aug 2025 | Viewed by 212 | Submission Open
Keywords: fibroblasts; injury repair; cardiac scar; extracellular matrix; fibrosis; angiogenesis; inflammation; cardioprotection
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Genetic Mechanisms of Neurological Disorders
edited by and Sara Duarte-Silva
submission deadline 20 Aug 2025 | Viewed by 202 | Submission Open
Keywords: neurodevelopmental disorders; neurodegenerative disorders; neuropsychiatric disorders; genetics; molecular biology; cellular models; animal models; pathogenesis; biomarkers; therapeutic targets; drug discovery; therapy  
(This special issue belongs to the Section Molecular Genetics and Genomics)
Molecular Advances on Solubility and Diffusivity in Water-Based Systems and in Biological Media submission deadline 20 Aug 2025 | Viewed by 46 | Submission Open
Keywords: water solubility  ; water-solute interactions  ; solvation; hydrophobic and hydrophilic effects  ; improving water solubility and prediction  ; solution of chemicals in biological media  ; diffusivity  ; drug transport and bioavailability; chemicals diffusivity across biological barriers
(This special issue belongs to the Section Physical Chemistry and Chemical Physics)
Analysis on Effector and Regulatory Molecules in Renal Diseases
edited by
submission deadline 20 Aug 2025 | Viewed by 33 | Submission Open
Keywords: effector molecules; regulatory molecules; membrane attack complex (MAC); perforin; granzyme; immune complex; neutrophil extracellular traps (NETs); proteolytic enzymes; reactive oxygen species; infection-related glomerulonephritis (IRGN); nephritis-associated plasmin receptor (NAPlr); streptococcal pyrogenic exotoxin B (SPEB); adhesion molecules
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Nrf1/2/3 and Other Antioxidant Transcription Factors in Health and Disease
edited by
submission deadline 20 Aug 2025 | Viewed by 21 | Submission Open
Keywords: transcription factor; oxidative stress; NRF1/2; NRF3; NFkB; P53; antioxidant-response elements; neurologial diseases; metabolic diseases; cancer
(This special issue belongs to the Section Molecular Immunology)
Advances in Genetics and Breeding Research in Horticultural Crops
edited by
submission deadline 20 Aug 2025 | Viewed by 8 | Submission Open
Keywords: horticultural crops; genomic sequencing; multi-omics technologies; molecular biology; gene editing; plant breeding; function of genes; molecular marker
Advances in Cardiometabolic Phenotypes of Pediatric Obesity
edited by Simona Georgiana Popa
submission deadline 22 Aug 2025 | Viewed by 554 | Submission Open
Keywords: cardiometabolic phenotypes of pediatric obesity; metabolomic profiles; microbiota; entero-insular axis; adipocytokines; precision therapy
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Endothelial Cells in Cancer: Molecular Advance
edited by Dae Joong Kim
submission deadline 22 Aug 2025 | Viewed by 75 | Submission Open
Keywords: tumor angiogenesis; metastasis; VEGFs; FGFs; Ang2; immune surveillance; antigen presentation; EC adhesion molecules; LYVE-1; lymphatic vessel; antigen-presenting cell; lymphocytes; high endothelial venule
(This special issue belongs to the Section Biochemistry)
New Insights into Bioactive Peptides: Design, Synthesis, Structure-Activity Relationship (2nd Edition) submission deadline 25 Aug 2025 | 5 articles | Viewed by 5357 | Submission Open
Keywords: peptides; protein-peptide interactions; PPI inhibition and modulation; peptide drugs; peptidomimetics; cyclic peptides; stapled peptides; diagnostic peptides; peptides for drug delivery; multidisciplinary approaches TRANSLATE with x English Arabic Hebrew Polish Bulgarian Hindi Portuguese Catalan Hmong Daw Romanian Chinese Simplified Hungarian Russian Chinese Traditional Indonesian Slovak Czech Italian Slovenian Danish Japanese Spanish Dutch Klingon Swedish English Korean Thai Estonian Latvian Turkish Finnish Lithuanian Ukrainian French Malay Urdu German Maltese Vietnamese Greek Norwegian Welsh Haitian Creole Persian   //   TRANSLATE with COPY THE URL BELOW Back EMBED THE SNIPPET BELOW IN YOUR SITE Enable collaborative features and customize widget: Bing Webmaster Portal Back //     This page is in English   Translate to Simplified Chinese         Afrikaans Albanian Amharic Arabic Armenian Azerbaijani Bengali Bulgarian Catalan Croatian Czech Danish Dutch English Estonian Finnish French German Greek Gujarati Haitian Creole Hebrew Hindi Hungarian Icelandic Indonesian Italian Japanese Kannada Kazakh Khmer Korean Kurdish (Kurmanji) Lao Latvian Lithuanian Malagasy Malay Malayalam Maltese Maori Marathi Myanmar (Burmese) Nepali Norwegian Pashto Persian Polish Portuguese Punjabi Romanian Russian Samoan Simplified Chinese Slovak Slovenian Spanish Swedish Tamil Telugu Thai Traditional Chinese Turkish Ukrainian Urdu Vietnamese Welsh   Always translate English to Simplified Chinese Never translate English Never translate admin.mdpi.com
(This special issue belongs to the Section Bioactives and Nutraceuticals)
New Insights into Epilepsy: From Molecular Physiology to Pathology
edited by Paolo Mainardi
submission deadline 25 Aug 2025 | Viewed by 342 | Submission Open
Keywords: epilepsy; molecular pathology; disease; therapeutic strategies; celluar advance
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Isolation and Biological Activities of Natural Products: Focus on Molecular Advance
edited by Pedro Ferreira and
submission deadline 25 Aug 2025 | Viewed by 60 | Submission Open
Keywords: natural products; sustainable isolation; biological activities; therapeutic potential; structure-activity relationships; omics technologies; bioavailability; functional foods; green chemistry; molecular docking
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Obesity: Different Perspectives Based on Molecular Physiology and Pathology
edited by Hector I. Rocha-Gonzalez
submission deadline 25 Aug 2025 | Viewed by 57 | Submission Open
Keywords: obesity; rational management; perspectives; new ideas; pharmacology; lifestyle modification; molecular advances
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Mechanistic Insights into Pharmacological and Non-Pharmacological Pain Therapies: From Cellular Responses to Therapy Outcomes
edited by
submission deadline 28 Aug 2025 | Viewed by 93 | Submission Open
Keywords: neuromodulation; neural plasticity; glial activation; endogenous pain modulation; neuroinflammation; therapeutic mechanisms
(This special issue belongs to the Section Molecular Pharmacology)
Genetic Analysis Based on CRISPR/Cas9 Technology: 2nd Edition
edited by and
submission deadline 30 Aug 2025 | 2 articles | Viewed by 2147 | Submission Open
Keywords: gene targeting (GT); homology-directed repair (HDR); homology-directed gene targeting (HGT); CRISPR/Cas; targeted mutagenesis; precision breeding; genetic analysis
(This special issue belongs to the Section Molecular Genetics and Genomics)
From Bench to Bedside: Well-Established and Emerging Preclinical Models in Cardiovascular Research
edited by and Veronica Dusi
submission deadline 30 Aug 2025 | 1 articles | Viewed by 1972 | Submission Open
Keywords: myocardial infarction; organ ischemia and reperfusion injury; hypertension; cardiovascular dysfunction; cardio-renal syndrome; stroke; arrhythmias; heart disease; heart failure; genetic disorders; translational medicine; organoids; bioreactors; organs on a chip; omics sciences; pharmacology; molecular biology; gene therapy; quantum biology
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
The Transcendental World of Plant Toxic Compounds
edited by
submission deadline 30 Aug 2025 | 1 articles | Viewed by 1894 | Submission Open
Keywords: alcaloids; biotic stress; defence; phenols; phytotoxins; secondary metabolism; terpenes
(This special issue belongs to the Section Molecular Plant Sciences)
Plant-Microbe Interaction: Current Status and Future Directions submission deadline 30 Aug 2025 | Viewed by 617 | Submission Open
Keywords: beneficial micro-organism; climate change; crop productivity; environmental stress; food production; plant growth; stress mitigation; yield
(This special issue belongs to the Section Molecular Plant Sciences)
Role of Quorum Sensing in Plant Microbiome: Advances and Prospects
edited by
submission deadline 30 Aug 2025 | Viewed by 232 | Submission Open
Keywords: quorum sensing; quorum quenching; rhizosphere signaling; signaling molecules; N-Acyl-L-homoserine lactones; AHLs; microbiome; chemical molecules; sustainable agriculture
(This special issue belongs to the Section Molecular Plant Sciences)
Plants Redox Biology
edited by
submission deadline 30 Aug 2025 | Viewed by 163 | Submission Open
Keywords: plant– environment interaction; stress physiology; plant redox signaling; plant hormones; plant– pathogen interaction; reactive oxygen species (ROS); reactive nitrogen species (RNS); ascorbate; flavonoid; glutathione
(This special issue belongs to the Section Molecular Plant Sciences)
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