Special Issues

Life publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Interdisciplinarity in Cardiovascular Diseases: From Pathophysiology to Diagnosis and Treatment—2nd Edition submission deadline 5 Mar 2025 | 10 articles | Viewed by 18362 | Submission Open
Keywords: interdisciplinary team; cardiovascular diseases; cardiovascular complications; gastro-esophago-enterology and hepatology; metabolic associated steato-hepatitis; gut microbiota; nephrocardiology; pulmonary diseases; rheumatology diseases; endocrinology diseases
(This special issue belongs to the Section Physiology and Pathology)
Laparoscopy and Treatment. An All-Encompassing Solution for Surgeons
edited by Niculae Iordache and Claudiu-Octavian Ungureanu
submission deadline 5 Mar 2025 | Viewed by 141 | Submission Open
Keywords: oncological; staging laparoscopy; tool; radical surgery; diagnostic
(This special issue belongs to the Section Medical Research)
Interdisciplinarity in Cardiovascular Pathology submission deadline 10 Mar 2025 | 1 articles | Viewed by 1136 | Submission Open
Keywords: cardiovascular disease; atherosclerosis; cardio-reno-metabolic syndrome; diabetes; obesity; obstructive pulmonary disease; sleep apnea syndrome; low-grade inflammation
(This special issue belongs to the Section Physiology and Pathology)
Etiology, Prediction and Prognosis of Ischemic Stroke
edited by , and Jiang Li
submission deadline 11 Mar 2025 | 2 articles | Viewed by 2882 | Submission Open
Keywords: ischemic stroke; recurrent stroke; etiology; machine learning; artificial intelligence; subtyping; prediction; prognosis; genetic risk factors; lifestyle factors; environmental factors; biomarkers; cerebrovascular diseases; prevention; treatment strategies
(This special issue belongs to the Section Physiology and Pathology)
Dermatology: Inflammatory Disorders and Future Perspectives
edited by
submission deadline 14 Mar 2025 | 5 articles | Viewed by 11017 | Submission Open
Keywords: psoriasis; atopic dermatitis; acne; rosacea; COVID-19; inflammatory skin diseases
(This special issue belongs to the Section Physiology and Pathology)
Soil–Plant–Microbe Interactions: The Role of Biostimulants and Agro-Environmental Implications
edited by Regina Gabilondo and
submission deadline 15 Mar 2025 | 1 articles | Viewed by 999 | Submission Open
Keywords: soil– plant– microbe system; biostimulants; rhizosphere; fertilizers; availability of mineral nutrients; microfaunal grazing; protozoa; nematode; mycorrhizae; microbial loop
(This special issue belongs to the Section Plant Science)
Biomarkers and Prognostic Markers in Cardiovascular Diseases
edited by and Serge Sicouri
submission deadline 20 Mar 2025 | 2 articles | Viewed by 1730 | Submission Open
Keywords: biomarkers; cardiovascular disease; prognostic markers; prognostic tools; cardiac disease; aortic disease
(This special issue belongs to the Section Medical Research)
Mammalian Gametogenesis, Fertilization and Early Embryogenesis: 2nd Edition
edited by
submission deadline 20 Mar 2025 | 1 articles | Viewed by 1036 | Submission Open
Keywords: mammalian reproduction; mammalian gametogenesis; mammalian fertilization; zygote; embryogenesis; spermatogenesis; oogenesis; sperm– egg interaction; zygotic activation
(This special issue belongs to the Section Animal Science)
Management of Patients with Diabetes
edited by Paola Simeone
submission deadline 20 Mar 2025 | Viewed by 153 | Submission Open
Keywords: prevention; diagnosis and therapies; type 2 diabetes (T2D); type 1 diabetes (T1D); diabetes mellitus; gestational diabetes mellitus (GDM)
(This special issue belongs to the Section Medical Research)
Environmental Exposure and Human Health: Morphological, Physiological and Clinical Consequences
edited by
submission deadline 21 Mar 2025 | 1 articles | Viewed by 1722 | Submission Open
Keywords: environmental risk; human health; morphological studies; physiological studies; molecular aspects; clinical implications; biomarkers; advanced imaging techniques; risk factors; mechanistic studies
(This special issue belongs to the Section Physiology and Pathology)
New Insights Into Leishmaniasis and Chagas Disease: Focus on Diagnosis and Genetic Characterization of Parasites: 2nd Edition
edited by and Cristina Ballart
submission deadline 21 Mar 2025 | 1 articles | Viewed by 1212 | Submission Open
Keywords: leishmania; leishmaniasis; chagas disease; American trypanosomiasis; Trypanosoma cruzi; diagnostics; genetic diversity; characterization; neglected tropical disease
(This special issue belongs to the Section Epidemiology)
Human Health Before, During, and After COVID-19
edited by Alessia Verduri
submission deadline 25 Mar 2025 | 12 articles | Viewed by 17996 | Submission Open
Keywords: COVID-19; telemedicine; pandemic-related anxiety; pandemic-related depression; long COVID; unvaccinated people; new SARS-CoV-2 variants
(This special issue belongs to the Section Epidemiology)
Diet and Vascular Disease submission deadline 25 Mar 2025 | 3 articles | Viewed by 4872 | Submission Open
Keywords: cardiovascular disease; cardiovascular risk; diet; dyslipidaemias; heart failure; human; hypertension; sodium; salt
(This special issue belongs to the Section Physiology and Pathology)
Movement Analysis and Electrophysiology in Neurological Pathologies
edited by , Francesco Piccione and
submission deadline 25 Mar 2025 | 1 articles | Viewed by 1658 | Submission Open
Keywords: movement analysis; neurological disorders; electrophysiology
(This special issue belongs to the Section Physiology and Pathology)
Advances in Medical Imaging of Animal Models for Human Diseases
edited by and Tsai-Hsien Hung
submission deadline 25 Mar 2025 | Viewed by 102 | Submission Open
Keywords: medical imaging; animal models; preclinical research; human disease; oncology
(This special issue belongs to the Section Medical Research)
Musculoskeletal Medicine in Rheumatic Diseases
edited by Florentin Ananu Vreju and Emilio Filippucci
submission deadline 26 Mar 2025 | 2 articles | Viewed by 1638 | Submission Open
Keywords: rheumatic disease; rheumatoid arthritis; spondylarthritis; microcrystal arthritis; musculoskeletal ultrasonography; biologic treatment; disease-modifying antirheumatic drugs; imagining techniques
(This special issue belongs to the Section Medical Research)
Innovative Approaches in Dermatological Therapies and Diagnostics submission deadline 28 Mar 2025 | Viewed by 211 | Submission Open
Keywords: dermatology; inflammatory diseases; skin cancer; non-invasive diagnosis; dermoscopy; confocal dermoscopy; targeted therapy; JAK inhibitors; biologics; artificial intelligence
(This special issue belongs to the Section Medical Research)
Recent Advances in Physiotherapy for Musculoskeletal
edited by Miguel Ángel Rosety-Rodríguez and
submission deadline 28 Mar 2025 | Viewed by 90 | Submission Open
Keywords: musculoskeletal rehabilitation; emerging technologies; virtual reality; artificial intelligence; inflammatory genetics; physiotherapy; sports medicine; functional recovery
(This special issue belongs to the Section Physiology and Pathology)
Sialic Acid and Sialic Acid Derivatives in Biomedicine
edited by and
submission deadline 30 Mar 2025 | Viewed by 169 | Submission Open
Keywords: sialic acid; drug development; sialidase inhibitors; sialylation; sialidase; biomarker
(This special issue belongs to the Section Physiology and Pathology)
Gender Medicine: Current Knowledge and Future Perspectives
edited by
submission deadline 30 Mar 2025 | Viewed by 124 | Submission Open
Keywords: gender; gender medicine; LGBTQ + health; health equity in gender medicine; intersectionality; pharmacology; reproductive health; chronic diseases; transgender healthcare; sex-specific healthcare
(This special issue belongs to the Section Medical Research)
What Is Life?
edited by and André Brack
submission deadline 31 Mar 2025 | 9 articles | Viewed by 17887 | Submission Open
Keywords: definition of life; origins of life; synthetic biology; theoretical biology; quantum biology; water; time; electrostatic potential; DNA; mutations; molecular interactions
(This special issue belongs to the Section Biochemistry, Biophysics and Computational Biology)
Recent Advances in Chemosensory-Based Behaviorally, Physiologically, and Molecularly Manipulated Technology of Pest Insects
edited by and Nanji Jiang
submission deadline 31 Mar 2025 | 8 articles | Viewed by 8877 | Submission Open
Keywords: insect pests; chemosensory reception; environmental cues; neural pathways; molecular function; pest management
(This special issue belongs to the Section Animal Science)
Feature Paper in Physiology and Pathology: 2nd Edition
edited by and Eleni Stamellou
submission deadline 31 Mar 2025 | 9 articles | Viewed by 7060 | Submission Open
Keywords: applied physiology; biomechanics; cardiovascular pathobiology; cell physiology; comparative pathology; comparative physiology
(This special issue belongs to the Section Physiology and Pathology)
Gastrointestinal Health: Clinical Research and Therapeutic Innovations
edited by
submission deadline 31 Mar 2025 | 8 articles | Viewed by 5813 | Submission Open
Keywords: gut microbiota; inflammatory bowel diseases; irritable bowel syndrome; gastroesophageal reflux disease; fatty liver disease; liver cirrhosis; probiotics; mediterranean diet; epidemiology; diagnosis; treatment; artificial intelligence
(This special issue belongs to the Section Medical Research)
Emerging Biomarkers: Recent Findings and Application in Pathological Condition Detection—2nd Edition submission deadline 31 Mar 2025 | 5 articles | Viewed by 5364 | Submission Open
Keywords: biomarkers; biological fluids; early diagnosis; laboratory medicine
(This special issue belongs to the Section Medical Research)
Implications of Bioactive Compounds in Lifelong Disorders submission deadline 31 Mar 2025 | 3 articles | Viewed by 3172 | Submission Open
Keywords: phytochemicals; functional food; oxidative stress; metabolic syndrome; neuroinflammation; antioxidant; polyphenols; diabetes; inflammatory bowel disease; natural products; neurodegenerative disease
(This special issue belongs to the Section Pharmaceutical Science)
Physical Medicine and Rehabilitation: Trends and Applications—3rd Edition submission deadline 31 Mar 2025 | 5 articles | Viewed by 3127 | Submission Open
Keywords: clinical physical medicine and rehabilitation; neurorehabilitation; cardiopulmonary rehabilitation; orthopedic rehabilitation; pediatric rehabilitation; geriatric rehabilitation; cancer rehabilitation; musculoskeletal pain management; physical therapy; occupational therapy; speech and swallowing therapy
(This special issue belongs to the Section Epidemiology)
Skin Technology and Artificial Intelligence in Dermatology
edited by Mohamad Goldust and Maria M. Tsoukas
submission deadline 31 Mar 2025 | 1 articles | Viewed by 2372 | Submission Open
Keywords: skin technology; artificial intelligence; machine learning
(This special issue belongs to the Section Medical Research)
Clinical Management and Prevention of Adverse Pregnancy Outcomes submission deadline 31 Mar 2025 | 4 articles | Viewed by 2233 | Submission Open
Keywords: pathologic pregnancies; ultrasound; clinical and molecular characteristics; fetal pathologies
(This special issue belongs to the Section Reproductive and Developmental Biology)
Ecotoxicity Effects of Metals and Microplastics on Aquatic Organisms
edited by Chiara Martino
submission deadline 31 Mar 2025 | 2 articles | Viewed by 1699 | Submission Open
Keywords: aquatic organisms; emerging contaminants; metals; microplastics; defense strategies; cell stress; heavy metals; environmental stress; pollution; ecotoxicology
(This special issue belongs to the Section Animal Science)
Evolutionary and Conservation Genetics: 3rd Edition
edited by and Ilenia Azzena
submission deadline 31 Mar 2025 | 1 articles | Viewed by 1403 | Submission Open
Keywords: evolutionary genetics; population genetics; conservation genetics; phylogeography; phylogenetics; phylodynamics; molecular taxonomy
(This special issue belongs to the Section Evolutionary Biology)
Non-coding RNAs: Genomics, Biogenesis, Mechanisms, and Functions
edited by
submission deadline 31 Mar 2025 | 1 articles | Viewed by 1367 | Submission Open
Keywords: ncRNA-interacting proteins; ncRNA modification; ncRNA biogenesis; ncRNA degradation; ncRNA decay; function; disease; therapeutic targets
(This special issue belongs to the Section Physiology and Pathology)
A Paradigm Shift in Airway and Pain Management—2nd Edition
edited by
submission deadline 31 Mar 2025 | 1 articles | Viewed by 1208 | Submission Open
Keywords: airway management; pain management; ultrasonography; motor activity; nerve block; anesthesia; conduction; regenerative medicine; multidisciplinary/comprehensive care program; transarterial embolization for pain management; joint denervation for pain management
(This special issue belongs to the Section Medical Research)
Sports Medicine: Nutritional Sciences and Nutritional Biochemistry: 2nd Edition
edited by
submission deadline 31 Mar 2025 | 1 articles | Viewed by 722 | Submission Open
Keywords: sport nutrition; sport supplementation; sport biochemistry; metabolomics; miRNA
(This special issue belongs to the Section Physiology and Pathology)
Prevention Data Collecting Technology or Methodology to Live a Safe, Secure, Comfortable, Healthy and Sustainable Life submission deadline 31 Mar 2025 | Viewed by 509 | Submission Open
(This special issue belongs to the Section Medical Research)
Synthesis and Evaluation of Novel Anticancer and Anti-Inflammatory Agents
edited by Po-Jen Chen, and Shun-Hua Chen
submission deadline 31 Mar 2025 | Viewed by 182 | Submission Open
Keywords: anticancer agents; anti-inflammatory agents; pharmacology; molecular and cell biology; drug design; medicinal chemistry; pharmacodynamics; pharmacokinetics; structure– activity relationship (SAR)
(This special issue belongs to the Section Pharmaceutical Science)
Space Medicine Ophthalmology: Insights from Molecular Observations to the Clinical Management of Ocular Risks in Microgravity
edited by Joshua Ong
submission deadline 31 Mar 2025 | Viewed by 165 | Submission Open
Keywords: spaceflight; space medicine; ophthalmology; space medicine; microgravity; cornea; retina; ocular surface
(This special issue belongs to the Section Astrobiology)
Plant Physiology: From Omic Analysis Toward Physiological Mechanism Research: 2nd Edition
edited by and Fang He
submission deadline 31 Mar 2025 | Viewed by 160 | Submission Open
Keywords: plant physiology; transcriptome; proteomics; gene regulatory network; bioinformation; omics; molecular mechanisms
(This special issue belongs to the Section Plant Science)
Molecular and Cellular Biology of Transplantation
edited by Robert Ramm and Sebastian G. Michel
submission deadline 31 Mar 2025 | Viewed by 157 | Submission Open
Keywords: xeno- and allotransplantation; ex vivo perfusion; costimulatory blockade; CAR Treg; accommodation
(This special issue belongs to the Section Physiology and Pathology)
Current Updates in Pharmacoepidemiology
edited by
submission deadline 31 Mar 2025 | Viewed by 131 | Submission Open
Keywords: pharmacoepidemiology; real-world data; medication safety; machine learning; big data analytics; personalized medicine; drug efficacy; population health; pharmacovigilance
(This special issue belongs to the Section Pharmaceutical Science)
Nephrology in the 21st Century: Native Kidney Diseases and Impact of Artificial Intelligence, and Advances in Renal Transplantation
edited by Marjan Afrouzian, Lukman Cheraghvandi and Jenna Reisler
submission deadline 31 Mar 2025 | Viewed by 120 | Submission Open
Keywords: Artificial Intelligence (AI); nephrology; native kidney diseases; renal transplantation
(This special issue belongs to the Section Medical Research)
Innovative Approaches in Breast Reconstruction: From Diagnostics to Treatment of Complications
edited by Eun Young Rha
submission deadline 31 Mar 2025 | Viewed by 114 | Submission Open
Keywords: breast reconstruction; imaging study; autologous tissue; implant; acellular dermal matrix; surgical outcome; scar
(This special issue belongs to the Section Medical Research)
Bone and Cartilage Fractures: Types, Diagnosis, Complications, Prevention and Treatment
edited by Massimiliano Leigheb, Gabriele Colò and
submission deadline 31 Mar 2025 | Viewed by 113 | Submission Open
Keywords: fracture; traumatology; diagnosis; surgery; osteosynthesis; reduction; cartilage; chondral; lesion; injury; rehabilitation; complication
(This special issue belongs to the Section Medical Research)
Dialysis submission deadline 31 Mar 2025 | Viewed by 112 | Submission Open
Keywords: hemodialysis; hemodiafiltration; peritoneal dialysis; home hemodialysis; incremental dialysis; dialyzer membrane; vascular access; dialysis adequacy; cardiovascular disease; infection; symptoms in dialysis; mineral bone disease; inflammation; anemia; frailty; quality of life
(This special issue belongs to the Section Medical Research)
Novel Approaches and Strategies in Nutrition and Feeding of Animals: 2nd Edition
edited by
submission deadline 31 Mar 2025 | Viewed by 107 | Submission Open
Keywords: animal nutrition; animal production efficiency; animal product quality (milk; eggs; meat); bioactive compounds; sustainability feeding management; advanced grazing management; feed aditives; alternative feed ingredients; fish nutrition; nutrition and health; human health
(This special issue belongs to the Section Animal Science)
Advances in Cardiac Arrest: Prognostic Performance and Management
edited by
submission deadline 31 Mar 2025 | Viewed by 102 | Submission Open
Keywords: cardiac arrest; resuscitation; emergency medicine; critical care medicine
(This special issue belongs to the Section Medical Research)
Exploring the Interplay between Diet, Microbiota, and Cancer submission deadline 31 Mar 2025 | Viewed by 83 | Submission Open
Keywords: microbiota/microbiome and cancer; dysbiosis; environmental pollutants; xenobiotic; metabolic disorders; diet; health/cancer; microbiota– host symbiosis; age diet; probiotics; prebiotics
(This special issue belongs to the Section Microbiology)
Vitamin D in Autoimmune and Infectious Diseases submission deadline 31 Mar 2025 | Viewed by 82 | Submission Open
Keywords: vitamin D; autoimmunity; rheumatoid arthritis; systemic lupus erythematosus; systemic sclerosis; infectious agents; COVID-19; SARS-CoV-2
(This special issue belongs to the Section Physiology and Pathology)
Molecular and Cellular Biology of Angiogenesis
edited by Roberta Marques Lassance-Soares
submission deadline 31 Mar 2025 | Viewed by 81 | Submission Open
Keywords: neovascularization; endothelial proliferation; vascular growth
(This special issue belongs to the Section Physiology and Pathology)
Lipid Metabolism, Regulation and Biosynthesis of Microalgae
edited by Yi Xin and
submission deadline 10 Apr 2025 | 3 articles | Viewed by 5368 | Submission Open
Keywords: microalgae; lipid biosynthesis; lipid metabolism; carbon and nitrogen metabolism; energy metabolism; genetic engineering; genome editing; environmental stress; signaling regulation; tag biosynthesis; biochemical regulation
(This special issue belongs to the Section Plant Science)
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