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Life publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advancements in Heart Failure Research

edited by Tzu-Hurng Cheng and

Ju-Chi Liu

submission deadline 31 Jan 2025 | 4 articles | Viewed by 5203 | Submission Open

Keywords: cardiac remodeling; biomarkers; precision medicine; patient-centered care; therapeutic innovations

(This special issue belongs to the Section Medical Research)

Interaction Between Dietary Components and Gut Microbiota: Their Effect on Human and Animal Health

edited by

Georgia Saxami

Dimitrios Arapoglou

and

Christos Eliopoulos

submission deadline 31 Jan 2025 | 2 articles | Viewed by 2890 | Submission Open

Keywords: gut microbiota; dietary components; disease prevention and development; probiotic and prebiotic; omics approaches; animals’ gut health

(This special issue belongs to the Section Microbiology)

Feature Papers in Medical Research: 3rd Edition

edited by

Christian Lehmann

submission deadline 31 Jan 2025 | 3 articles | Viewed by 2793 | Submission Open

Keywords: dermatological research; cancer research; cardiovascular research; general medicine; gastroenterological research; hematological research; immunological research; infectious diseases research; metabolism and endocrinology; nervous system research; nursing; pediatrics; pulmonary research; psychiatric research; rehabilitation; renal and urinary research; reproductive research and women's health; rheumatological research; skeletal and muscular research; vision research

(This special issue belongs to the Section Medical Research)

Resistance Training Is Medicine

edited by

Daniel J. McDonough

submission deadline 31 Jan 2025 | 2 articles | Viewed by 2037 | Submission Open

Keywords: resistance training; resistance exercise; physical activity; sedentary behavior; strength training; chronic disease; risk factors; obesity; physical health

(This special issue belongs to the Section Epidemiology)

Novel Finding in Cancer Genomics

edited by

Da-Tian Bau

submission deadline 31 Jan 2025 | 1 articles | Viewed by 1821 | Submission Open

Keywords: bladder cancer; prostate cancer; renal cell carcinoma; upper tract urothelial carcinoma

(This special issue belongs to the Section Genetics and Genomics)

Common and Novel Markers of Inflammation and Tissue Damage in Various Pathological Conditions

edited by

Marzena Tylicka

Joanna Kamińska

and

Olga Koper-Lenkiewicz

submission deadline 31 Jan 2025 | 1 articles | Viewed by 1177 | Submission Open

Keywords: body fluids; cytokines; damage-associated molecular patterns (DAMPS); inflammatory response; injury; markers of inflammation and tissue damage; metalloproteinases; novel markers; pathological conditions; proteasome; tissue damage; tissue repair processes; various diseases

(This special issue belongs to the Section Physiology and Pathology)

Advancements in Postoperative Management of Patients After Surgery

edited by

Antonino Zanghi

Luigi La Via

Antonino Maniaci

and Alessandro Cappellani

submission deadline 31 Jan 2025 | 1 articles | Viewed by 818 | Submission Open

Keywords: surgery; ERAS; postoperative management; recovery; pain

(This special issue belongs to the Section Medical Research)

Antioxidants—Key Players in Innovative Pharmaceutical Products and Food Supplements

edited by Bogdan Manolescu,

Eliza Oprea

and

Magdalena Mititelu

submission deadline 31 Jan 2025 | Viewed by 807 | Submission Open

Keywords: antioxidants; delivery systems; controlled release; bioavailability; bioactive natural products; food supplements

(This special issue belongs to the Section Pharmaceutical Science)

Cardioncology: From Molecular Mechanisms to Advanced Imaging and New Treatments

edited by

Carla Contaldi

, Giuseppe Pacileo and

Paolo Calabrò

submission deadline 31 Jan 2025 | Viewed by 381 | Submission Open

Keywords: cardiotoxicity; echocardiography; cardiac magnetic resonance; cardiac computed tomography; serum cardiac biomarkers; cancer therapy; arrhythmias; cardiotoxicity treatment

(This special issue belongs to the Section Physiology and Pathology)

Novel Diagnostic and Therapeutic Approaches in Congenital Heart Diseases

edited by

Ştefana Moisǎ

and

Eliza Elena Cintezǎ

submission deadline 31 Jan 2025 | Viewed by 345 | Submission Open

Keywords: congenital heart disease; echocardiography; interventional cardiology; multimodal imaging; heart surgery

(This special issue belongs to the Section Medical Research)

The Regulation Networks of the Circadian Clock in Plants

edited by

Mathias Foo

submission deadline 31 Jan 2025 | Viewed by 218 | Submission Open

Keywords: plant circadian; circadian clock; transcriptional; post-transcriptional; epigenetic mechanisms

(This special issue belongs to the Section Plant Science)

Fertility Preservation and Sterility Treatment

edited by

Stefano Canosa

submission deadline 31 Jan 2025 | Viewed by 189 | Submission Open

Keywords: fertility preservation; oncofertility; cryopreservation; basic research; gonadotoxicity; oocyte cryopreservation; sperm cryopreservation; ovarian tissue transplantation; assisted reproductive technologies

(This special issue belongs to the Section Medical Research)

Epidemiology Studies of Cardiovascular Diseases in Older Adults

edited by Nadya Kagansky

submission deadline 31 Jan 2025 | Viewed by 149 | Submission Open

Keywords: cardiovascular diseases in older adults; gerontology; hypertension; hyperlipidemia; diabetes; obesity

(This special issue belongs to the Section Epidemiology)

Inflammation and Natural Products: 2nd Edition

edited by

Azahara Rodríguez-Luna

Salvador González

and Irene García Domínguez

submission deadline 31 Jan 2025 | Viewed by 137 | Submission Open

Keywords: natural products; inflammation; biological activity; anti-inflammatory activity; antioxidant activity; anticancer potential; terrestrial products; marine products; phytochemistry; pharmacology

(This special issue belongs to the Section Pharmaceutical Science)

Advancing Nanotechnology in Cancer Theranostics

edited by

Yulia Merkher

submission deadline 31 Jan 2025 | Viewed by 110 | Submission Open

Keywords: nanotechnology; cancer; nanoscale materials; nanoparticles; diagnostic accuracy; therapeutic efficacy; metastasis detection and prediction; targeted drug delivery; personalized cancer therapy

(This special issue belongs to the Section Medical Research)

The Multifaceted Role of B Cells in the Pathogenesis of Rheumatic Diseases

edited by Achilleas Floudas

submission deadline 31 Jan 2025 | Viewed by 105 | Submission Open

Keywords: B cells; antibodies; arthritis; RNAseq; ACPA; RF; antigen-specific

(This special issue belongs to the Section Cell Biology and Tissue Engineering)

Innovations in Pathology and Viral Oncology

edited by Luca Roncati

submission deadline 17 Feb 2025 | Viewed by 119 | Submission Open

Keywords: pathology; viral oncology; gynecological oncology; hematological oncology; head and neck tumors; human papilloma virus (HPV); HPV-test; PAP-test; oncoviruses; cancer

(This special issue belongs to the Section Physiology and Pathology)

Research Update on Pancreaticobiliary Endotherapy

edited by Mateusz Jagielski

submission deadline 18 Feb 2025 | Viewed by 164 | Submission Open

Keywords: acute pancreatitis; chronic pancreatitis; pancreatic necrosis; pancreatic pseudocyst; endoscopic retrograde cholangiopancreatography (ERCP); endoscopic ultrasound (EUS); transpapillary drainage; transmural drainage; endoscopic necrosectomy

(This special issue belongs to the Section Medical Research)

Immuno-Pathogenesis Skin Diseases: Novel Molecular Targets and Biomarkers: 2nd Edition

edited by

Annunziata Raimondo

submission deadline 20 Feb 2025 | 2 articles | Viewed by 3117 | Submission Open

Keywords: chronic inflammatory skin diseases; immunopathogenesis; inflammatory pathways; molecular target; biomarkers; psoriasis; atopic dermatitis; hidradenitis suppurativa; urticaria; skin cancer

(This special issue belongs to the Section Physiology and Pathology)

Robot-Assisted Surgery: New Trends and Solutions

edited by

Davide Ghinolfi

and Felipe Boff Maegawa

submission deadline 20 Feb 2025 | 2 articles | Viewed by 2505 | Submission Open

Keywords: robotic surgery; minimally invasive abdominal surgery; minimally invasive liver surgery; minimally invasive pancreatic surgery

(This special issue belongs to the Section Medical Research)

Gynecological Endocrinology: From Physiological Mechanisms to Clinical Practice

edited by Ralitsa Robeva

submission deadline 20 Feb 2025 | Viewed by 288 | Submission Open

Keywords: PCOS; hypothalamic amenorrhea; congenital adrenal hyperplasia; hypogonadotropic hypogonadism; premature ovarian insufficiency (POI)

(This special issue belongs to the Section Physiology and Pathology)

Vascular Disease: Etiologic, Diagnostic, Prognostic and Therapeutic Research—2nd Edition

edited by

Dan Mircea Olinic

and

Agata Stanek

submission deadline 21 Feb 2025 | 10 articles | Viewed by 9431 | Submission Open

Keywords: vascular diseases; etiology; diagnosis; prognosis; therapy

(This special issue belongs to the Section Medical Research)

Effects of Physical Training on Youth Athletes' Physical Performance, Health and Well-Being

edited by

Jorge Arede

Thomas Dos'Santos

and Oliver Gonzalo-Skok

submission deadline 25 Feb 2025 | 5 articles | Viewed by 5415 | Submission Open

Keywords: biological maturation; strength; endurance; speed; sleep; psychosocial; physical activity; conditioning; long-term athlete development; body composition

(This special issue belongs to the Section Physiology and Pathology)

Therapeutic Effects of Natural Products on Human Diseases: 2nd Edition

edited by

Seung Ho Lee

submission deadline 25 Feb 2025 | 2 articles | Viewed by 1728 | Submission Open

Keywords: natural products; natural extracts; cancer; neurodegenerative diseases; immunological disorders; metabolic diseases; oriental medicine; microorganisms; algae; functional foods

(This special issue belongs to the Section Pharmaceutical Science)

Structural Biology of Pathogens and Drug Development

edited by

Litao Sun

submission deadline 25 Feb 2025 | Viewed by 199 | Submission Open

Keywords: antiviral and antibacterial medications; emerging infectious diseases; drug-resistant pathogens; structural biology; drug discovery and design; medicinal chemistry; drug screening

(This special issue belongs to the Section Microbiology)

Pathophysiology, Diagnosis and Treatment of Immune Disease

edited by

Miriana D'Alessandro

and Lucia Vietri

submission deadline 26 Feb 2025 | 3 articles | Viewed by 5286 | Submission Open

Keywords: immune disease treatment; autoimmunity; biomarkers; treatment; immunology

(This special issue belongs to the Section Physiology and Pathology)

Optogenetics and Light-Induced Processes in Synthetic Biology

edited by

Pasquale Stano

submission deadline 26 Feb 2025 | Viewed by 410 | Submission Open

(This special issue belongs to the Section Synthetic Biology and Systems Biology)

Pathophysiology, Diagnosis, and Treatments of Intestinal Diseases

edited by Amosy Ephreim M’Koma

submission deadline 26 Feb 2025 | Viewed by 219 | Submission Open

Keywords: gastrointestinal disease/disorders; pathophysiology; diagnostics and treatment

(This special issue belongs to the Section Physiology and Pathology)

Carbon and Nitrogen Cycles in Terrestrial Ecosystems

edited by

Naiqing Pan

submission deadline 26 Feb 2025 | Viewed by 202 | Submission Open

Keywords: process-based modeling and machine learning; field experiments and meta-analysis; terrestrial carbon and nitrogen cycles; role of living organisms in biogeochemical cycles

(This special issue belongs to the Section Diversity and Ecology)

Helicobacter pylori

edited by

Ovidiu Pop

and

Simona Gurzu

submission deadline 28 Feb 2025 | 8 articles | Viewed by 31204 | Submission Open

Keywords: H. Pylori; cancers; antioxidative process; diagnostic methods

(This special issue belongs to the Section Microbiology)

Effects of Environmental Factors on Challenges of Plant Breeding

edited by

Katalin Magyar-Tábori

and

Nóra Mendler-Drienyovszki

submission deadline 28 Feb 2025 | 7 articles | Viewed by 10173 | Submission Open

Keywords: plant breeding; winter hardiness; sowing time; adaptation to cold/frost; physiology of cold/frost tolerance; snow cover

(This special issue belongs to the Section Plant Science)

Understanding Comorbidities in Gynecologic Diseases: A Holistic Approach to Women’s Health

edited by

Noemi Salmeri

and

Giovanni Buzzaccarini

submission deadline 28 Feb 2025 | 3 articles | Viewed by 2680 | Submission Open

Keywords: women’ s health; women’ s disease; systemic diseases; comorbities; systemic approach; multi-organ

(This special issue belongs to the Section Reproductive and Developmental Biology)

Noninvasive Skin Imaging: The Present and the Future in General Dermatology

edited by

Bijan Safai

and

Banu Farabi

submission deadline 28 Feb 2025 | 3 articles | Viewed by 2296 | Submission Open

Keywords: skin imaging; dermatoscopy; dermatology imaging; dermatosurgery; clinical dermatology

(This special issue belongs to the Section Medical Research)

Alzheimer’s Disease: Recent Developments in Pathogenesis, Diagnosis, and Therapy

edited by

Ivana Shawkatová

and

Juraj Javor

submission deadline 28 Feb 2025 | 2 articles | Viewed by 2288 | Submission Open

Keywords: Alzheimer’ s disease; biomarkers; epigenetics; genetics; genomics; immune mediators; neurodegeneration; neuroinflammation; proteomics; risk factors; therapy; transcriptomics

(This special issue belongs to the Section Physiology and Pathology)

Physical Activity in People with Cognitive Impairment

edited by

Luca Puce

and

Nicola Luigi Bragazzi

submission deadline 28 Feb 2025 | 2 articles | Viewed by 1965 | Submission Open

Keywords: cognition; mild cognitive impairment; Alzheimer’ s disease; dementia; physical activity; sport; athletes with disabilities; para-athletes

(This special issue belongs to the Section Physiology and Pathology)

Fertility Preservation in Female and Male Benign and Malignant Conditions: 2nd Edition

edited by Arianna D’Angelo, Suman Dadhich and Ali Thwaini

submission deadline 28 Feb 2025 | 1 articles | Viewed by 1893 | Submission Open

Keywords: oncofertility; fertility preservation; cancer; oncology; fertility; egg freezing; embryo freezing; sperm freezing; freezing; IVF; premature ovarian failure; premature ovarian insufficiency; testicular failure; ovarian tissue freezing; PESA; TESE

(This special issue belongs to the Section Reproductive and Developmental Biology)

Management of Ischemia and Heart Failure—2nd Edition

edited by

Cristian Mornoş

submission deadline 28 Feb 2025 | 2 articles | Viewed by 1424 | Submission Open

Keywords: cardiac ischemia; heart failure; therapy; medical innovation; emerging technologies; care strategies; prognosis; treatment efficacy; clinical protocols; personalized therapies

(This special issue belongs to the Section Medical Research)

Unlocking New Biochemical Pathways: A Bridge for Drug Development in Human and Animal Diseases

edited by

Vincenzo Vestuto

Ignazio Restivo

and

Giuseppe Piegari

submission deadline 28 Feb 2025 | 1 articles | Viewed by 1384 | Submission Open

Keywords: drug discovery; omics sciences; veterinary sciences; oxidative stress; bioactive compounds; inflammation; cancer; neurodegeneration; cell death

(This special issue belongs to the Section Pharmaceutical Science)

Clinical Research in Male Reproduction

edited by Andrea Crafa,

Aldo E. Calogero

and Richard Quinton

submission deadline 28 Feb 2025 | 2 articles | Viewed by 1326 | Submission Open

Keywords: male infertility; male fertility; male sub-fertility; idiopathic male infertility; male reproduction

(This special issue belongs to the Section Medical Research)

Algae—a Step Forward in the Sustainability of Resources: 2nd Edition

edited by

Graciliana Lopes

and

Leonel Pereira

submission deadline 28 Feb 2025 | 2 articles | Viewed by 1000 | Submission Open

Keywords: macroalgae; microalgae; cyanobacteria; bioactive compounds; biomass production; pharmaceuticals; nutraceuticals; cosmetics; food/feed; CO2 sequestrations; water treatment; IMTA; ecosystem services; biofuels; biopesticides; green extraction methods

(This special issue belongs to the Section Microbiology)

Latest Advances in Dermatology: From Molecular Insights into Clinical Applications

edited by

Emilio García Mouronte

and Alfonso Perez-Gonzalez

submission deadline 28 Feb 2025 | 1 articles | Viewed by 896 | Submission Open

Keywords: dermatology; personalized medicine; molecular diagnostic techniques; targeted therapies; skin cancer; inflammatory skin diseases

(This special issue belongs to the Section Medical Research)

Reconstruction of Bone Defects

edited by

Jörg Eschweiler

and

Philipp Kobbe

submission deadline 28 Feb 2025 | 1 articles | Viewed by 891 | Submission Open

Keywords: bone and fracture biomechanics; bone healing; critical size bone defects; fracture non-union; inflammation; joint arthroplasty and fracture osteosynthesis; implant designs; materials proprieties; patient selection; primary and revision settings

(This special issue belongs to the Section Medical Research)

New Insights into Parkinson’s Disease: From Molecular Basis to Therapy

edited by

Kallirhoe Kalinderi

submission deadline 28 Feb 2025 | Viewed by 473 | Submission Open

Keywords: Parkinson’ s disease; neurodegeneration; genes; GWAs; polygenic risk score; therapy; precision medicine; pathways; pharmacogenetics; surgicogenomics

(This special issue belongs to the Section Medical Research)

Bone Remodeling

edited by

Tada-aki Kudo

submission deadline 28 Feb 2025 | Viewed by 282 | Submission Open

Keywords: bone remodeling; osteoblast; osteoclast; osteocyte; osteoporosis

(This special issue belongs to the Section Cell Biology and Tissue Engineering)

Multi-Omics for Diagnosing Diseases: Bioinformatics Approaches and Integrative Data Analyses

edited by

Emanuel Maldonado

and

Imran Khan

submission deadline 28 Feb 2025 | Viewed by 252 | Submission Open

Keywords: bioinformatics; computer hardware; software; and methods; first-/second-/third-generation sequencing; clinical genomics; mendelian diseases; whole-exome sequencing; evolutionary and comparative genomics; whole-genome sequencing; multi-omics; microbiome diseases

(This special issue belongs to the Section Genetics and Genomics)

Human-Specific RNA Metabolism: Mechanisms, Dysregulation, and Disease Implications

edited by Xiangbo Ruan

submission deadline 28 Feb 2025 | Viewed by 238 | Submission Open

Keywords: human-specific RNA metabolism; mechanisms; dysregulation; disease implications

(This special issue belongs to the Section Physiology and Pathology)

Urinary Microbiome and Genitourinary System Disorders: 2nd Edition

edited by

Mohammad Sajjad Rahnama'i

and

Philip Van Kerrebroeck

submission deadline 28 Feb 2025 | Viewed by 176 | Submission Open

Keywords: microbiome; microbiota; bacteria; 16s-RNA sequencing; bladder; urinary tract infection; urgency; incontinence; lower urinary tract symptoms (LUTS)

(This special issue belongs to the Section Microbiology)

Cardiac Arrhythmias: Physiological Mechanisms, Clinical Insights, and Epidemiological Research

edited by Thomas A. Agbaedeng

submission deadline 28 Feb 2025 | Viewed by 170 | Submission Open

Keywords: cardiac arrhythmias; atrial fibrillation; sudden cardiac death; ventricular arrhythmias; electrophysiological remodelling; structural remodelling; omics; risk factors; (epi)genetics; GWAS; PheWas; polygenic risk; machine learning models; natural language models

(This special issue belongs to the Section Medical Research)

Effects of Exercise on Susceptibility to Environmental and Disease Stressors

edited by Suzanne M. Schneider

submission deadline 28 Feb 2025 | Viewed by 149 | Submission Open

Keywords: aerobic exercise; physical activity; steps per day; cytokines; exerkines; hepatokines; myokines; adipokines; gut– brain axis; immune function; obesity; diabetes; cardiovascular disease; hypertension; osteoporosis; tumor growth; cognitive function; dementia; depression; sleep disorders; hyperthermia; asthma

(This special issue belongs to the Section Physiology and Pathology)

Updates in Genetic Susceptibility to Cancers

edited by Chia-Wen Tsai

submission deadline 28 Feb 2025 | Viewed by 141 | Submission Open

Keywords: cancer genomics; genome-wide association study (GWAS); single nucleotide polymorphism (SNP); genotype-phenotype correlation; prognosis; diagnosis

(This special issue belongs to the Section Medical Research)

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