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B Vitamin Supplements: Benefits, Deficiencies and Toxicity

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Micronutrients and Human Health".

Deadline for manuscript submissions: closed (20 February 2023) | Viewed by 5095

Special Issue Editor


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Guest Editor
1. Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong 999077, China
2. CUHK Jockey Club Centre of Positive Ageing, The Chinese University of Hong Kong, Hong Kong 999077, China
3. CUHK Jockey Club Centre for Osteoporosis Care and Control, The Chinese University of Hong Kong, Hong Kong 999077, China
Interests: dementia; osteoporosis; nutrition; health services

Special Issue Information

Dear Colleagues,

B vitamins have important functions in energy and amino acid metabolism, neuronal health and hemopoiesis. Although deficiency states are uncommon among the general population, B vitamins in different combinations are commonly prescribed or bought over the counter for health maintenance and clinical conditions, e.g., neuropathic pain, anxiety and depression. In addition, high doses of some B vitamins have been utilized for their therapeutic effects, e.g., enhancement of cognitive function or mood, lipid lowering, etc. Yet some B vitamins have harmful effects in higher doses. On the other hand, there has been increasing interest in the impact of vitamin B supplements on gut microbiota and interactions of vitamin B supplements with other nutrients, drugs and genetic factors.

For this Special Issue, we are interested in papers investigating how vitamin B supplements can impact on health both positively and negatively.

Prof. Dr. Timothy CY Kwok
Guest Editor

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Keywords

  • B vitamin
  • dietary supplements
  • toxicity
  • vitamin B deficiency
  • food-drug interactions
  • nutrigenomics

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Published Papers (1 paper)

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Research

13 pages, 409 KiB  
Article
Maternal Serum Vitamin B12 during Pregnancy and Offspring Autism Spectrum Disorder
by Andre Sourander, Sanju Silwal, Heljä-Marja Surcel, Susanna Hinkka-Yli-Salomäki, Subina Upadhyaya, Ian W. McKeague, Keely Cheslack-Postava and Alan S. Brown
Nutrients 2023, 15(8), 2009; https://doi.org/10.3390/nu15082009 - 21 Apr 2023
Cited by 2 | Viewed by 4709
Abstract
This study examined the association between maternal serum vitamin B12 levels during early pregnancy and offspring autism spectrum disorders (ASD) and subtypes. Based on a Finnish national birth cohort, case offspring (n = 1558) born in 1987–2007 and diagnosed with ASD by 2015 [...] Read more.
This study examined the association between maternal serum vitamin B12 levels during early pregnancy and offspring autism spectrum disorders (ASD) and subtypes. Based on a Finnish national birth cohort, case offspring (n = 1558) born in 1987–2007 and diagnosed with ASD by 2015 were matched with one control on date of birth, sex and place of birth. Maternal vitamin B12 levels were measured during first and early second trimesters of pregnancy. High maternal vitamin B12 levels (≥81th percentile) was associated with increased risk for offspring childhood autism, adjusted odds ratio, 1.59, 95% confidence interval 1.06–2.41 (p = 0.026). No significant associations were observed between maternal vitamin B12 levels and offspring Asperger’s or pervasive developmental disorder/NOS. Full article
(This article belongs to the Special Issue B Vitamin Supplements: Benefits, Deficiencies and Toxicity)
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