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Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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MMPs and EMMPRIN/CD147 in Physiological and Pathological Processes 2.0

edited by

Eric Huet

submission deadline 30 Apr 2025 | 3 articles | Viewed by 6627 | Submission Open

Keywords: matrix metalloproteinases; EMMPRIN; tissue remodeling; cell interactions; physiopathology

(This special issue belongs to the Section Molecular and Translational Medicine)

Oncolytic Viruses and Combinatorial Immunotherapy for Cancer

edited by

Zong Sheng Guo

and

Michael H. Lehmann

submission deadline 30 Apr 2025 | 2 articles | Viewed by 5185 | Submission Open

Keywords: oncolytic virus; antitumor immunity; cold tumor; tumor antigen; cancer vaccine; immunotherapy; combinatorial therapy; immune checkpoint blockade

(This special issue belongs to the Section Immunology and Immunotherapy)

Molecular Mechanisms and Treatments on Musculoskeletal Disorders

edited by

Wei-Bin Hsu

and

Meng-Huang Wu

submission deadline 30 Apr 2025 | 2 articles | Viewed by 5028 | Submission Open

Keywords: osteoporosis; sarcopenia; osteoblast; osteoclast; myoblast; satellite cell

(This special issue belongs to the Section Molecular and Translational Medicine)

Pancreatitis: Etiology, Pathology, and Treatment

edited by Laura Gaman, Mariana Jinga and Stoian Irina

submission deadline 30 Apr 2025 | 3 articles | Viewed by 4641 | Submission Open

Keywords: acute and chronic pancreatitis; pathophysiology; autoimmunity; novel biomarkers; innovative endoscopic; personalized treatment

(This special issue belongs to the Section Molecular and Translational Medicine)

The End of the COVID-19 Pandemic—What Is Currently Known and What Could Have Been Useful Four Years Ago? (2nd Edition)

edited by

Monika Zajkowska

and

Monika Gudowska-Sawczuk

submission deadline 30 Apr 2025 | 3 articles | Viewed by 4308 | Submission Open

Keywords: COVID-19; SARS-CoV-2; pandemic; diagnosis; biomarkers; treatment; immunity; inflammation; cytokines; vaccine

(This special issue belongs to the Section Molecular and Translational Medicine)

Molecular Processes Underlying Pathogenesis and Advanced Therapies for Genodermatosis

edited by

Natividad Cuadrado-Corrales

submission deadline 30 Apr 2025 | 2 articles | Viewed by 3269 | Submission Open

Keywords: genodermatosis; rare skin disease; molecular pathology; clinical diagnostic; gene therapy

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

Advances in the Treatment of Kidney and Upper Urinary Tract Cancers: Second Edition

edited by

Łukasz Zapała

submission deadline 30 Apr 2025 | 2 articles | Viewed by 3124 | Submission Open

Keywords: renal cancer; urothelial cancer; immunotherapy; systemic therapy

(This special issue belongs to the Section Cancer Biology and Oncology)

Advances in Macrophage-Based Immunotherapy

edited by

Dolores Ortiz-Masiá

submission deadline 30 Apr 2025 | 2 articles | Viewed by 2503 | Submission Open

Keywords: macrophages; fibrosis; cancer; chronic inflammation; autophagy; apoptosis; senescence; immunotherapy

(This special issue belongs to the Section Immunology and Immunotherapy)

Interaction between Liver and Adipose Tissues

edited by Yongke Lu

submission deadline 30 Apr 2025 | 2 articles | Viewed by 2450 | Submission Open

Keywords: ethanol; bile acid; gluconeogenesis; steatosis; obesity; fatty acid oxidation; extracellular vesicles

(This special issue belongs to the Section Cell Biology and Pathology)

From Bench to Bedside: Advances in Non-small Cell Lung Cancer in the Era of Precision Oncology

edited by Iyare Izevbaye

submission deadline 30 Apr 2025 | 2 articles | Viewed by 2433 | Submission Open

Keywords: non-small-cell lung cancer; precision medicine; liquid biopsy; biomarkers; predictive modeling; comprehensive genomic profiling; biomarkers; immuno-oncology; lung cancer biology

(This special issue belongs to the Section Cancer Biology and Oncology)

New Diagnostic and Therapeutic Approaches in Diabetic Microvascular Complications, 2nd Edition

edited by

Ana Maria Dascalu

and

Dragos Serban

submission deadline 30 Apr 2025 | 1 articles | Viewed by 2378 | Submission Open

Keywords: diabetic retinopathy; diabetic foot ulcer; inflammatory biomarkers; microbiota; novel therapies

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Advances in the Pharmacology of Neuroendocrine Tumors

edited by

Maja Cigrovski Berković

submission deadline 30 Apr 2025 | 2 articles | Viewed by 2370 | Submission Open

Keywords: pancreatic neuroendocrine tumors; gastrointestinal endocrine tumors; treatment; systemic therapy; somatostatin; interferon-alpha; molecular-targeted agents; tumor apoptosis; symptom control

(This special issue belongs to the Section Cancer Biology and Oncology)

Molecular Research in Substance Abuse: Toxicity, Neurotoxicity and Neuropathological Findings

edited by

Angelo Montana

and

Arianna Giorgetti

submission deadline 30 Apr 2025 | 1 articles | Viewed by 2311 | Submission Open

Keywords: drug abuse; neurotoxicity; neuropathology; histopathology; immunohistochemistry; toxicology; toxicogenetics; in vitro; in vivo; and in silico models; hypoxic– ischaemic brain injury; biomarkers; behavioral addictions

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Head-and-Neck Sarcomas: Exploring Ways for Their Optimal Treatment

edited by Recine Federica,

Silvia Vanni

Alessandro De Vita

and Giacomo Miserocchi

submission deadline 30 Apr 2025 | 1 articles | Viewed by 1880 | Submission Open

Keywords: sarcomas; citogenetic features; molecular profile; novel therapeutic approaches; rare neoplasms

(This special issue belongs to the Section Cancer Biology and Oncology)

Modulation of Anti-tumor Immunity and Tumor Microenvironment

edited by Yu-Jen Chen

submission deadline 30 Apr 2025 | 1 articles | Viewed by 1863 | Submission Open

Keywords: anti-tumor immunity; tumor microenvironment; immunotherapy; chemotherapy; target therapy; hyperthermia; radiotherapy

(This special issue belongs to the Section Immunology and Immunotherapy)

Molecular Mechanisms of Steroid Hormone Action—2nd Edition

edited by

Omar Cauli

submission deadline 30 Apr 2025 | 1 articles | Viewed by 1802 | Submission Open

Keywords: oestrogen; androgens; thyroid; adrenal gland; menopause; cancer

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Diagnosis, Pathogenesis and Treatment of Pancreatic Ductal Adenocarcinoma

edited by

Teresa Perra

and

Alberto Porcu

submission deadline 30 Apr 2025 | 1 articles | Viewed by 1768 | Submission Open

Keywords: pancreatic cancer; pancreatic ductal adenocarcinoma; treatment; management; complications; vascular reconstruction; neoadjuvant therapy

(This special issue belongs to the Section Cancer Biology and Oncology)

Advanced Biomedical Research on COVID-19 (2nd Edition)

edited by

Federica Perelli

submission deadline 30 Apr 2025 | 2 articles | Viewed by 1618 | Submission Open

Keywords: SARS-CoV-2; COVID-19; antibody; infection; immunity

(This special issue belongs to the Section Immunology and Immunotherapy)

Pathogenesis, Diagnosis, and Treatment of Respiratory Diseases

edited by

Te-Chun Shen

submission deadline 30 Apr 2025 | 1 articles | Viewed by 1482 | Submission Open

Keywords: COPD; asthma; interstitial lung disease; lung cancer; pneumonia; tuberculosis; respiratory failure; ARDS; COVID-19; obstructive sleep apnea

(This special issue belongs to the Section Cell Biology and Pathology)

Tumor Immune Microenvironment and Novel Strategies for Cancer Immunotherapy

edited by Sidra Islam

submission deadline 30 Apr 2025 | 1 articles | Viewed by 1360 | Submission Open

Keywords: tumor microenvironment cancer immunotherapy; immune markers; tumor infilterating immune cells; tumors

(This special issue belongs to the Section Immunology and Immunotherapy)

Endocrine Cancers: Pathophysiology and Therapy

edited by

Rajeev Parameswaran

and Amit Agrawal

submission deadline 30 Apr 2025 | 1 articles | Viewed by 1348 | Submission Open

Keywords: thyroid; parathyroid; adrenal; paraganglioma; genomes; transcriptomes; signalling pathways; precision medicine

(This special issue belongs to the Section Cancer Biology and Oncology)

Epigenetic Regulation in Cancer Progression

edited by

Yonghwan Shin

submission deadline 30 Apr 2025 | 1 articles | Viewed by 1298 | Submission Open

Keywords: cancer progression; epigenetic regulation; gene expression; dysregulation; therapeutic targets

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

Advanced Research in Atrial Fibrillation

edited by

Wern Yew Ding

submission deadline 30 Apr 2025 | 1 articles | Viewed by 1195 | Submission Open

Keywords: atrial fibrillation; arrhythmia; electrophysiology; cardiovascular; mechanism; laboratory; experimental

(This special issue belongs to the Section Molecular and Translational Medicine)

Biomarkers in Pain

edited by

Mats B. Eriksson

and

Anders O. Larsson

submission deadline 30 Apr 2025 | 1 articles | Viewed by 1191 | Submission Open

Keywords: analgesia; biomarker; CSF; cytokine; inflammation; neuropathy; neurotransmitter; pain; QoL; sensitization; sensory

(This special issue belongs to the Section Molecular and Translational Medicine)

Emerging Research and Applications in Target and Drug Discovery Field

edited by Alfonso Trezza

submission deadline 30 Apr 2025 | 1 articles | Viewed by 1151 | Submission Open

Keywords: molecular dynamics and docking simulation; molecular modeling; target and drug discovery; precision medicine; circular bioeconomy

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Role of Factors in Embryo Implantation and Placental Development

edited by

Micol Massimiani

and Valentina Lacconi

submission deadline 30 Apr 2025 | 1 articles | Viewed by 1131 | Submission Open

Keywords: placental development; implantation; embryo development; pregnancy disorders; endometrium; implantation failure; recurrent pregnancy loss; decidualization

(This special issue belongs to the Section Molecular and Translational Medicine)

Involvement of Free Radicals in Health and Disease

edited by

Laura Lõpez-Pingarrõn

submission deadline 30 Apr 2025 | 1 articles | Viewed by 1055 | Submission Open

Keywords: free radicals; mitochondrial ; peroxisomes; cytochrome P450

(This special issue belongs to the Section Cell Biology and Pathology)

PPARs in Health and Disease, 2nd Edition

edited by

Maria Konstandi

submission deadline 30 Apr 2025 | 1 articles | Viewed by 1037 | Submission Open

Keywords: PPARα ; PPARβ /δ ; PPARγ ; nuclear receptor; lipid homeostasis; glucose homeostasis; neurodegenerative disorders; dyslipidemia; atherosclerosis; cardiovascular disease; cancer

(This special issue belongs to the Section Cell Biology and Pathology)

Morphomolecular Characterization of Neoplastic and Pre-neoplastic Lesions in Solid Tumors

edited by Giuseppe Nicolò Fanelli and

Edoardo Francini

submission deadline 30 Apr 2025 | 1 articles | Viewed by 789 | Submission Open

Keywords: solid cancer; molecular pathology; histopathology; diagnostic; prognostic and predictive biomarkers

(This special issue belongs to the Section Cell Biology and Pathology)

Genetic Research on Neuropsychiatric Disorders and Complex Human Diseases

edited by Wen Zhang

submission deadline 30 Apr 2025 | 1 articles | Viewed by 690 | Submission Open

Keywords: neuropsychiatric disorders; complex human diseases; genetic research; omics data analysis; high-throughput sequencing; machine learning; disease mechanism

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

Tendinopathy and Myopathy: From Molecular Basis to Therapy

edited by

Simon Fuk-Tan Tang

and Carl Pai Chu Chen

submission deadline 30 Apr 2025 | 1 articles | Viewed by 586 | Submission Open

Keywords: musculoskeletal disorder; tendinopathy; myopathy

(This special issue belongs to the Section Molecular and Translational Medicine)

Molecular and Translational Research in Cardiovascular Disease

edited by

Simon Lebek

and

Philipp Hegner

submission deadline 30 Apr 2025 | 1 articles | Viewed by 566 | Submission Open

Keywords: cardiovascular disease; heart failure; atrial fibrillation; arrhythmias; lon channels; sleep apnea

(This special issue belongs to the Section Molecular and Translational Medicine)

Atrial Fibrillation and Related Complications: Pathogenetic, Diagnostic and Therapeutic Perspectives

edited by Jien Jiun Chen

submission deadline 30 Apr 2025 | Viewed by 547 | Submission Open

Keywords: atrial fibrillation; complication; genetics; pathogenesis; ablation; stroke prevention

(This special issue belongs to the Section Molecular and Translational Medicine)

Exploring the Interplay between Endothelial Cells and Immune Cells in the Pathogenesis of Metabolic Diseases

edited by

Kenneth Chat Pan Cheung

and Rodrigo A. Loiola

submission deadline 30 Apr 2025 | Viewed by 522 | Submission Open

Keywords: tumor microenvironment; blood vessels; immunology; immunotherapy; drug delivery and mechanism; metabolic reprogramming; chemoresistance

(This special issue belongs to the Section Molecular and Translational Medicine)

From Molecules to Minds: Translational Breakthroughs in Preclinical Psychiatry

edited by

Masaru Tanaka

Simone Battaglia

and

Sandra Barbalho

submission deadline 30 Apr 2025 | Viewed by 345 | Submission Open

Keywords: depression; anxiety; bipolar disorder; post-traumatic stress disorder; mental disorders; epigenomics; psychiatric disorders/genetics; circadian rhythm; sex characteristics; mitochondrial dysfunction; neurotoxins; intergenerational transmission; cannabinoid receptor modulators; adolescent neuroplasticity; synaptic pruning; psychoimmunology; preclinical studies; translational medical research; neuroplasticity; neuromodulation; phytochemicals; plant extracts; transcranial magnetic stimulation

(This special issue belongs to the Section Molecular and Translational Medicine)

Convergence of Allergology and Immunology: Unveiling Mechanistic Insights

edited by

Kinga Lis

submission deadline 30 Apr 2025 | Viewed by 333 | Submission Open

Keywords: allergy; hypersensitivity; allergens; immunological mechanisms; immunological diagnostics; immunotherapy

(This special issue belongs to the Section Immunology and Immunotherapy)

Advanced Research in Secondary Immunodeficiency in Oncohematological Diseases

edited by

Giuseppe Murdaca

and

Sebastiano Gangemi

submission deadline 30 Apr 2025 | Viewed by 320 | Submission Open

Keywords: secondary immunodeficiencies and opportunistic infections; secondary immunodeficiencies and B-lymphocytes; secondary immunodeficiencies and hematological diseases; secondary immunodeficiencies and cancers; secondary immunodeficiencies and novel cancer treatments; secondary immunodeficiencies and oxidative stress

(This special issue belongs to the Section Immunology and Immunotherapy)

The Development of Cancer Immunotherapy

edited by

Satoshi Wada

submission deadline 30 Apr 2025 | Viewed by 303 | Submission Open

Keywords: cancer immunotherapy; immune checkpoint inhibitors; genetically modified T-cell therapy; hematological cancers; solid tumors

(This special issue belongs to the Section Cancer Biology and Oncology)

Nano-Based Drug Delivery and Drug Discovery

edited by

Xiangli Shao

submission deadline 30 Apr 2025 | Viewed by 299 | Submission Open

Keywords: nanotechnology; drug discovery; drug delivery; nanocarriers; nanomaterials; drug targeting; drug release; drug therapeutic

(This special issue belongs to the Section Nanomedicine and Nanobiology)

Bioinformatics Analysis of miRNA for Human Health and Disease

edited by Jihwan Ha

submission deadline 30 Apr 2025 | Viewed by 289 | Submission Open

Keywords: bioinformatics; computational biology; machine learning; multi-omics data analysis; biomarker detection; biomedical AI convergence; medical and public health informatics

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

Emerging Trends in Traumatic Brain Injury

edited by David James Davies

submission deadline 30 Apr 2025 | Viewed by 278 | Submission Open

Keywords: photonic approaches to the central nervous system; NIRS; Raman; LLLT; cold laser therapy; brain biomarkers; concussion and mild TBI; severe TBI

(This special issue belongs to the Section Molecular and Translational Medicine)

Molecular Research of Neurological and Psychiatric Disorders

edited by

Yuen Gao

submission deadline 30 Apr 2025 | Viewed by 275 | Submission Open

Keywords: molecular biology; neurodegenerative disorders; psychiatry; biomarkers; therapeutic targets

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Relationship between Insulin Resistance/Hyperinsulinemia and the Development of Atherosclerosis/Arteriosclerosis as the Cause of Cardiovascular Diseases

edited by

Maria Grau

submission deadline 30 Apr 2025 | Viewed by 266 | Submission Open

Keywords: atherosclerosis; arteriosclerosis; insulin resistance; hyperinsulinemia; cardiovascular diseases; carotid artery diseases; coronary artery disease; peripheral vascular diseases

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Thoracic Malignancies: From Pathophysiology to Novel Therapeutic Approaches

edited by Yanyun Gao

submission deadline 30 Apr 2025 | Viewed by 251 | Submission Open

Keywords: malignant pleural mesothelioma; diagnosis; molecular subtypes; chemotherapy; target therapy; MPM metabolism; biomarkers; immunotherapy; preclinical models for MPM

(This special issue belongs to the Section Cancer Biology and Oncology)

Oxidative Stress and Proteinopathy in Alzheimer's Disease

edited by Chanchal Sharma

submission deadline 30 Apr 2025 | Viewed by 246 | Submission Open

Keywords: Alzheimer’ s disease; oxidative stress; synaptic dysfunction; abnormal protein accumulation; gliosis; neuroinflammation; antioxidant therapies

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

New Insights and Latest Advances in Corneal and Ocular Surface Diseases

edited by Isabella M. Y. Cheung and Akilesh Gokul

submission deadline 30 Apr 2025 | Viewed by 244 | Submission Open

Keywords: corneal disease; ocular surface disease prevention; diagnosis; management; pathobiology; epidemiology; health service delivery

(This special issue belongs to the Section Molecular and Translational Medicine)

Mechanisms, Implications, and Therapeutic Targets in Infectious Diseases

edited by Mihai Lazăr and Oana Săndulescu

submission deadline 30 Apr 2025 | Viewed by 234 | Submission Open

Keywords: infectious diseases; virus; antibiotics; pathophysiology; molecular mechanism; therapeutic management

(This special issue belongs to the Section Immunology and Immunotherapy)

Immune Mechanisms in Dermatology

edited by

Olga Simionescu

submission deadline 30 Apr 2025 | Viewed by 229 | Submission Open

Keywords: skin innate immunity; skin acquired immunity; biologics; immunofluorescence; PRP; viral skin infections; bullous disorders; connective tissue disorders; skin cancer immunology

(This special issue belongs to the Section Immunology and Immunotherapy)

Molecular Mechanisms of Myeloid Cell Differentiation and Resistance to Anti-Tumor Immunity

edited by Laura Strauss

submission deadline 30 Apr 2025 | Viewed by 229 | Submission Open

Keywords: emergency myelopoiesis; MDSC; immunotherapy resistance; dysfunctional myeloid differentiation; TME in cold tumors

(This special issue belongs to the Section Cancer Biology and Oncology)

The Neuropharmacology of Cannabinoids: Developments in Medicine

edited by

Tibor Markus Brunt

submission deadline 30 Apr 2025 | Viewed by 221 | Submission Open

Keywords: THC; CBD; cannabis; endocannabinoid system; therapeutic; disease; health

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

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