Special Issues

Brain Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Headache: Advances in Pathophysiology, Clinical Presentations and Therapeutic Options
edited by
submission deadline 30 May 2025 | Viewed by 114 | Submission Open
Keywords: migraine; comorbidities; pathophysiology; pharmacological interventions; non-pharmacological interventions; mechanisms
(This special issue belongs to the Section Systems Neuroscience)
Relationships Between Disordered Sleep and Mental Health
edited by Anne M. Fink
submission deadline 31 May 2025 | 2 articles | Viewed by 2723 | Submission Open
Keywords: circadian rhythms; depression; genetics and genomics; rapid eye movement sleep behavior disorder; schizophrenia; sleep deprivation; shift– work sleep disorder; substance use disorder; suicide
(This special issue belongs to the Section Neuropsychiatry)
Brain Tumors: From Molecular Basis to Therapy
edited by Paolo Tini and Giuseppe Minniti
submission deadline 31 May 2025 | 3 articles | Viewed by 2665 | Submission Open
Keywords: brain tumors; molecular pathways; targeted therapy; diagnostic biomarkers; predictive biomarkers; therapeutic resistance
(This special issue belongs to the Section Neuro-oncology)
Aging-Related Changes in Memory and Cognition
edited by Anna Christakou
submission deadline 31 May 2025 | 2 articles | Viewed by 1641 | Submission Open
Keywords: aging; quality of life; cognitive/physical health; neurodegenerative diseases; geriatric physiotherapy; memory; cognition; attention; prevention; therapeutic treatments
(This special issue belongs to the Section Neurodegenerative Diseases)
Brain Stimulation Treatments for Memory Disorders submission deadline 31 May 2025 | 1 articles | Viewed by 971 | Submission Open
Keywords: DBS; tACS; tDCS; TUS; memory loss; plasticity; cognition; biochemistry
(This special issue belongs to the Section Systems Neuroscience)
Understanding the Functioning of Brain Networks in Health and Disease
edited by
submission deadline 31 May 2025 | Viewed by 197 | Submission Open
Keywords: brain networks; cognitive dysfunction; diffusion tensor imaging (DTI); electroencephalography (EEG); functional connectivity; functional magnetic resonance imaging (fMRI); magnetoencephalography (MEG); neurological disorders; neuroplasticity; psychiatric disorders; artificial intelligence; deep learning; neural networks; signal complexity
(This special issue belongs to the Section Neurotechnology and Neuroimaging)
State of the Art in Multisensory Integration: Predicting Age-Related Clinical Outcomes
edited by Jeannette R. Mahoney
submission deadline 1 Jun 2025 | Viewed by 287 | Submission Open
Keywords: multisensory integration; sensorimotor integration; aging; mobility; balance; falls; cognition; dementia
(This special issue belongs to the Section Sensory and Motor Neuroscience)
The Gut–Brain Axis: Exploring the Interactions Between the Microbiota and the Nervous System
edited by Kyle Gobrogge
submission deadline 1 Jun 2025 | Viewed by 49 | Submission Open
Keywords: gut– brain axis; microbiota– neuron interactions; neurological functions and disorders; animal models; behavior and cognition
(This special issue belongs to the Section Neural Control of Peripheral Function)
The Use of Chemogenetics and Optogenetics on Understanding the Neurobiology of Brain Disorders
edited by and
submission deadline 6 Jun 2025 | Viewed by 593 | Submission Open
Keywords: chemogenetics; optogenetics; DREADDs; brain disorders; neurobiology of disease
From Bench to Bedside: Motor–Cognitive Interactions—2nd Edition
edited by
submission deadline 10 Jun 2025 | 2 articles | Viewed by 2622 | Submission Open
Keywords: motor control and motor learning; movement; cognitive functions; falls; diagnosis; intervention; cognitive– motor training; cognition; fMRI
(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)
Current Research in Neurosurgery
edited by , Manlio Barbarisi and Lucas Alverne Freitas De Albuquerque
submission deadline 10 Jun 2025 | 1 articles | Viewed by 992 | Submission Open
Keywords: CSN tumor; glioblastoma; skull base; vertebral metastasis; spinal surgery; cerebral aneurysm; AVM; cavernoma; epilepsy
(This special issue belongs to the Section Neurosurgery and Neuroanatomy)
Biomarkers in Neurodegenerative Diseases: Advancements and Future Directions
edited by Fausto Roveta
submission deadline 10 Jun 2025 | Viewed by 174 | Submission Open
Keywords: Alzheimer’ s disease; Parkinson’ s disease; neurodegenerative disorders; biomarkers; neuroimaging
(This special issue belongs to the Section Neurodegenerative Diseases)
Role of Inflammation, Oxidative Stress, and Metabolic Dysfunction in Neurodevelopmental and Neurodegenerative Diseases: Pharmacological Targets and Therapeutic Interventions
edited by
submission deadline 13 Jun 2025 | 5 articles | Viewed by 6434 | Submission Open
Keywords: neuroinflammation; oxidative stress; mitochondrial dysfunction; metabolism; metabolomics; neurodegenerative diseases; neurodevelopmental diseases; pharmacological targets; potential drugs
(This special issue belongs to the Section Neurodegenerative Diseases)
Mental Health: From a Neurobiology Perspective submission deadline 13 Jun 2025 | 1 articles | Viewed by 2327 | Submission Open
Keywords: neurobiology; mental health; psychiatric disorders; neurotransmission; signaling pathway; genetic and epigenetic factors; neurodevelopment; inflammation; therapeutic interventions; translational and clinical research
(This special issue belongs to the Section Molecular and Cellular Neuroscience)
Exploration of the Brain Structural Changes in Patients with Mental Illness
edited by
submission deadline 15 Jun 2025 | Viewed by 183 | Submission Open
Keywords: psychiatric diseases; human brain connectome; biomarkers; endophenotypes
(This special issue belongs to the Section Neuropsychiatry)
Heterogeneity in Cognitive Aging: From Healthy Aging to Neurodegenerative Disease
edited by Yuta Katsumi, and Bradford C. Dickerson
submission deadline 15 Jun 2025 | Viewed by 91 | Submission Open
Keywords: aging; cognition; cognitive impairment; subjective cognitive decline; neurodegeneration; Alzheimer’ s disease; prognostication; brain imaging; neuromodulation; interventions
(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)
New Challenges in the Study of Cognitive Impairment in Parkinson’s Disease
edited by and Laura Colautti
submission deadline 16 Jun 2025 | 2 articles | Viewed by 2212 | Submission Open
Keywords: Parkinson’ s disease; cognitive impairment; assessment; intervention; executive functions; learning; decision making; creativity; cognitive reserve
(This special issue belongs to the Section Neurodegenerative Diseases)
Prediction and Prevention of Psychotic Disorders
edited by Francesco Monaco and Annarita Vignapiano
submission deadline 20 Jun 2025 | 1 articles | Viewed by 1515 | Submission Open
Keywords: psychotic disorders; early identification; prevention; biomarkers; genetics; psychosocial interventions
(This special issue belongs to the Section Neuropsychiatry)
Molecular Motors in Neuronal Homeostasis and Neurodegeneration submission deadline 20 Jun 2025 | Viewed by 524 | Submission Open
Keywords: molecular motors; kinesins; dynein; myosins; neuronal homeostasis; neuronal development; cellular trafficking; synaptic plasticity; biomarkers of early diagnosis; neurodegeneration
(This special issue belongs to the Section Molecular and Cellular Neuroscience)
Neurofunctional Basis of Language Processing—2nd Edition submission deadline 20 Jun 2025 | Viewed by 139 | Submission Open
Keywords: language neurological disorders; non-invasive; brain mapping; neural networks; plasticity
(This special issue belongs to the Section Neurolinguistics)
Neuropsychological Impact and Quality of Life in Chronic Illness
edited by Nicoletta Ciccarelli
submission deadline 20 Jun 2025 | Viewed by 137 | Submission Open
Keywords: chronic disease; HIV; cancer; cardiovascular disease; neurodegeneration; aging; cognitive impairment; cognitive evaluation; quality of life; patient reported outcome (PRO) measures
(This special issue belongs to the Section Neuropsychology)
Neurosurgery: Minimally Invasive Surgery in Brain and Spine
edited by Christopher Ahuja
submission deadline 25 Jun 2025 | Viewed by 161 | Submission Open
Keywords: minimally invasive surgery; neurosurgery; brain; spine
(This special issue belongs to the Section Neurosurgery and Neuroanatomy)
Multisensory Perception of the Body and Its Movement
edited by Monica Gori, Lara Coelho and Silvia Zanchi
submission deadline 27 Jun 2025 | 1 articles | Viewed by 618 | Submission Open
Keywords: body; space; spatial navigation; development; blindness multisensory
(This special issue belongs to the Section Sensory and Motor Neuroscience)
What Impact Does Lack of Sleep Have on Mental Health? submission deadline 28 Jun 2025 | 2 articles | Viewed by 3836 | Submission Open
Keywords: ADHD; Alzheimer's; anxiety; autism; bipolar disorder; CBT-I; chronotherapy; circadian rhythm; cognitive function; depression; eating disorders; emotional regulation; epilepsy; executive function; insomnia; jet lag; memory consolidation; mental health; multiple sclerosis; neurobiological mechanisms; neurodevelopmental disorders; neuropsychiatric disorders; OCD; Parkinson's disease; personality disorders; PTSD; schizophrenia; self-harm; shift work; sleep deprivation; sleep disturbances; sleep quality; social cognition; substance use disorders; suicidal ideation; wearable technology
(This special issue belongs to the Section Neuropsychiatry)
Integrating Advanced Imaging Techniques and Computational Models in Headache Research
edited by Catherine S. Hubbard
submission deadline 28 Jun 2025 | Viewed by 80 | Submission Open
Keywords: personalized medicine; migraine; headache disorders; machine learning; deep learning; neuroimaging; animal models; neuromodulation; fMRI; neural networks
(This special issue belongs to the Section Neuroscience of Pain)
New Advances in Neuroimmunology and Neuroinflammation
edited by , , Jing Sun and Matheus Uba Chupel
submission deadline 30 Jun 2025 | 3 articles | Viewed by 3365 | Submission Open
Keywords: neuroinflammation; neuroimmunology; glia; neurodegenerative diseases; cytokines; chemokines
(This special issue belongs to the Section Molecular and Cellular Neuroscience)
The Relationship Between Sleep and the Brain: New Insights into Sleep Disorders and Their Effects on Mental Health, Cognition, and Quality of Life
edited by
submission deadline 30 Jun 2025 | 2 articles | Viewed by 2302 | Submission Open
Keywords: sleep; REM sleep; circadian rhythm; melatonin; mood disorders; delta sleep; clock genes
(This special issue belongs to the Section Sleep and Circadian Neuroscience)
New Advances in the Development of New Drugs and Treatment Targets for Brain Cancers (2nd Edition) submission deadline 30 Jun 2025 | 1 articles | Viewed by 1550 | Submission Open
Keywords: gliomas; targeted therapy; blood– brain barrier; tumor microenvironment; molecular and cellular biology
(This special issue belongs to the Section Neuro-oncology)
Clinical Research on Sleep Disorders: Opportunities and Challenges
edited by
submission deadline 30 Jun 2025 | 1 articles | Viewed by 1118 | Submission Open
Keywords: innovation; personalized management; sleep disorders; telemonitoring; treatment
(This special issue belongs to the Section Sleep and Circadian Neuroscience)
Minimally Invasive Surgery for Brain and Skull Base Tumors submission deadline 30 Jun 2025 | 1 articles | Viewed by 1054 | Submission Open
Keywords: minimally invasive surgery; keyhole approaches; endoscopic surgery; stereotactic surgery; parafascicular surgery; brain tumors; neuro-oncology; skull base tumors
(This special issue belongs to the Section Neurosurgery and Neuroanatomy)
Neural Correlates of Art and Multisensory Perception submission deadline 30 Jun 2025 | Viewed by 895 | Submission Open
Keywords: neuroaesthetics; empirical aesthetics; visual perception; auditory perception; multisensory perception; art perception; music perception
(This special issue belongs to the Section Behavioral Neuroscience)
Translational EEG Biomarkers in Animal Models: Bridging Pre-Clinical Findings to Human Neuroscience
edited by and Cestmir Vejmola
submission deadline 30 Jun 2025 | 1 articles | Viewed by 633 | Submission Open
Keywords: EEG; ECoG; biomarker; animal model; pre-clinical
(This special issue belongs to the Section Neurotechnology and Neuroimaging)
Recent Advances in Neuroscience: Theoretical, Applied, and Experimental Research
edited by
submission deadline 30 Jun 2025 | Viewed by 573 | Submission Open
Keywords: neuroscience; genetics; brain; optogenetics; fMRI; MRI; TMS; tDCS; gene therapy; evolutionary neuroscience; psychiatric disorders
(This special issue belongs to the Section Systems Neuroscience)
Fetal Foundations of Cognition: Tracing Neurodevelopmental Pathways from an Integrated Perspective
edited by Pasquale Anthony Della Rosa and Cristina Baldoli
submission deadline 30 Jun 2025 | Viewed by 305 | Submission Open
Keywords: fetal neurodevelopment; neuroimaging techniques; cognitive outcomes; integrated perspectives; methodological innovations
(This special issue belongs to the Section Developmental Neuroscience)
The Role of Awareness in Visuomotor Control, Perception, and Spatial Attention submission deadline 30 Jun 2025 | Viewed by 229 | Submission Open
Keywords: visual awareness; visual perception; action; visuospatial attention; visuomotor integration
(This special issue belongs to the Section Behavioral Neuroscience)
Pain Memory: Assessment and Clinical Implications submission deadline 30 Jun 2025 | Viewed by 185 | Submission Open
Keywords: pain memory; psychosocial; pain chronification; pain medicine; pain assessment; pain neuroscience
(This special issue belongs to the Section Neuroscience of Pain)
Spinal Cord Injury
edited by Mark H. Tuszynski and Paul Lu
submission deadline 30 Jun 2025 | Viewed by 169 | Submission Open
Keywords: spinal cord injury; axonal regeneration; neural stem cells; neural progenitor cells; synaptic connection; neuronal relay
(This special issue belongs to the Section Molecular and Cellular Neuroscience)
The Latest Perspectives on Brain Tumor Surgery and Cognitive Rehabilitation
edited by Luca Zigiotto and Silvio Sarubbo
submission deadline 30 Jun 2025 | Viewed by 168 | Submission Open
Keywords: brain tumor surgery; awake surgery; cognitive impairments; neuropsychology; cognitive rehabilitation; structural and functional connectivity; cognitive functions; quality of life; high-grade gliomas; low-grade gliomas
(This special issue belongs to the Section Neurosurgery and Neuroanatomy)
Emotional Brain Development in Children
edited by Gemma Reynolds
submission deadline 30 Jun 2025 | Viewed by 137 | Submission Open
Keywords: emotional brain development; neurodevelopmental disorders; neural plasticity; genetic and environmental influences; atypical emotional development; emotional resilience and vulnerability
(This special issue belongs to the Section Developmental Neuroscience)
Immune-Mediated Disorders in Neurology and Their Management in the Era of Current and Emerging Treatments submission deadline 30 Jun 2025 | Viewed by 134 | Submission Open
Keywords: multiple sclerosis; neuromyelitis optica spectrum disorders (NMOSD); myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD); central nervous system; immune-mediated disease; disease modifying treatment; disease management; personalized medicine
(This special issue belongs to the Section Systems Neuroscience)
Psychological Approaches to the Understanding and Treatment of Psychological Difficulties in Individuals with Neurodegenerative Diseases
edited by
submission deadline 15 Jul 2025 | 1 articles | Viewed by 823 | Submission Open
Keywords: psychotherapy; psychological interventions; emotional distress; behavioural difficulties; neurodegenerative diseases; dementia; Huntington’ s disease; Parkinson’ s disease; motor neuron disease; amyotrophic lateral sclerosis
(This special issue belongs to the Section Behavioral Neuroscience)
Beyond Symptoms: How Brain Imaging is Revolutionizing Early Mental Health Disorders
edited by Annarita Vignapiano and Francesco Monaco
submission deadline 15 Jul 2025 | Viewed by 369 | Submission Open
Keywords: early-stage mental illness; brain imaging; MRI; biomarkers; personalized treatment
(This special issue belongs to the Section Neuropsychiatry)
Trends in Spinal Muscular Atrophy and Duchenne Muscular Dystrophy
edited by Alberto Dubrovsky
submission deadline 15 Jul 2025 | Viewed by 151 | Submission Open
Keywords: spinal muscular atrophy (SMA); Duchenne muscular dystrophy (DMD); neuromuscular disorders; therapies; new drugs
(This special issue belongs to the Section Neuromuscular and Movement Disorders)
Diagnosis and Management of Developmental Coordination Disorders
edited by Andrea Utley and Michael Wade
submission deadline 15 Jul 2025 | Viewed by 44 | Submission Open
Keywords: developmental coordination disorder; movement control; motor learning difficulties; assessment; intervention
(This special issue belongs to the Section Developmental Neuroscience)
Language, Communication and the Brain—2nd Edition submission deadline 15 Jul 2025 | Viewed by 42 | Submission Open
Keywords: cognitive; attention; working memory; executive functions; linguistic; language planning; speech production; fluency; sensorimotor; hearing; speech and language production; neurotypical; neurodiverse; autism; apraxia; dysarthria; stuttering; speech sound disorders; artificial intelligence; data science; theoretical; data-driven
(This special issue belongs to the Section Neurolinguistics)
AI-Driven Integration of Multimodal Imaging and Clinical Data for Long COVID: Mapping Brain-Behavior Associations and Treatment Outcomes submission deadline 20 Jul 2025 | 1 articles | Viewed by 900 | Submission Open
Keywords: artificial intelligence  ; neuroinflammation  ; cognitive dysfunction  ; multimodal imaging  ; neural connectivity  ; deep learning  ; neurocognitive assessment
(This special issue belongs to the Section Neurotechnology and Neuroimaging)
Eye-Tracking Monitoring of Neurological and Psychiatric Conditions Across Life Span submission deadline 20 Jul 2025 | 1 articles | Viewed by 783 | Submission Open
Keywords: gaze patterns; eye tracking; mild cognitive impairment; multiple sclerosis; neurodevelopmental disorders; saccades
(This special issue belongs to the Section Behavioral Neuroscience)
Lifestyle and Risk Factors for Multiple Sclerosis submission deadline 20 Jul 2025 | Viewed by 334 | Submission Open
Keywords: multiple sclerosis; lifestyle; risk factors; nutrition; pollution; sleep quality; progression
(This special issue belongs to the Section Neurodegenerative Diseases)
Psychedelic and Interventional Psychiatry
edited by
submission deadline 20 Jul 2025 | Viewed by 286 | Submission Open
Keywords: psychedelics; ketamine; interventional psychiatry; psychedelic medicine; LSD; DMT; psilocybin; MDMA; depression; anxiety; end of life; palliative medicine; treatment-resistant depression; OCD; anorexia nervosa; eating disorders; nitrous oxide; TMS; DBS; alcohol use disorders; substance use disorders; trauma; post-traumatic stress disorders; PTSD; ketamine and other psychedelic use disorders
(This special issue belongs to the Section Neuropsychiatry)
Emerging Trends in Youth Mental Health
edited by
submission deadline 20 Jul 2025 | Viewed by 42 | Submission Open
Keywords: mental health; adolescent mental health; young adult; stress; psychological; social media; climate change; identity development; digital health; school health services
(This special issue belongs to the Section Neuropsychology)
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