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Fermentation
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Feature Review Papers in Industrial Fermentation 2023
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Feature Review Papers in Industrial Fermentation 2023

A special issue of Fermentation (ISSN 2311-5637). This special issue belongs to the section "Industrial Fermentation".

Deadline for manuscript submissions: closed (31 December 2023) | Viewed by 19532

Special Issue Editors

Dr. Diomi Mamma

E-Mail Website
Guest Editor
Biotechnology Laboratory, School of Chemical Engineering, National Technical University of Athens, Athens, Greece
Interests: biochemical engineering; fermentation biotechnology; bioreactor design; valorization of agro-industrial wastes and food wastes for biofuels; kinetic modeling; halogenated hydrocarbons degradation; mass transfer phenomena; hydrolytic enzymes (purification, characterization); bio-scouring of cotton fabrics; growth of microalgae
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. Xiaoqing Lin

E-Mail Website
Guest Editor
School of Chemical Engineering and Light Industry, Guangdong Provincial Key Laboratory of Plant Resources Biorefinery, Guangdong University of Technology, Guangzhou 510006, China
Interests: biofuels (ethanol and butanol); biomass pretreatment; downstream processing; lignocellulosic biorefineries; adsorption and separation; platform chemicals
Special Issues, Collections and Topics in MDPI journals
Dr. Alessio Siciliano

E-Mail Website
Guest Editor
Department of Chemical and Environmental Engineering, Università della Calabria, 87036 Cosenza, Italy
Interests: anaerobic digestion; biogas; bioreactors; organic waste pretreatment processes; water and wastewater treatment
Special Issues, Collections and Topics in MDPI journals
Dr. Konstantinos G. Kalogiannis

E-Mail Website
Guest Editor
Department of Chemical Engineering, University of Western Macedonia (UOWM), Kozani, Greece
Interests: biorefineries; biofuels; delignification and fractionation technologies; biomass and wastes valorization; pyrolysis; heterogeneous catalysis; thermochemical conversion technologies
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue aims to collect high-quality review papers in all fields of industrial fermentation. We encourage researchers from related fields to contribute review papers highlighting the latest developments in industrial fermentation (including fermentation for the production of chemicals, materials, biofuels, and pharmaceuticals; environmental bioprocesses and the biodegradation of pollutants; and biorefinery), or to invite relevant experts and colleagues to do so. Full-length comprehensive reviews will be preferred.

This Special Issue aims to share these scientific findings as widely as possible.

Dr. Diomi Mamma
Prof. Dr. Xiaoqing Lin
Dr. Alessio Siciliano
Dr. Konstantinos G. Kalogiannis
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Fermentation is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2100 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

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Further information on MDPI's Special Issue polices can be found here.

Related Special Issue

Published Papers (6 papers)

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Review

21 pages, 5232 KiB  
Review
Filamentous Fungi as Bioremediation Agents of Industrial Effluents: A Systematic Review
by Fernanda Maria Rosa, Thaís Fernandes Mendonça Mota, Cleverson Busso, Priscila Vaz de Arruda, Patrícia Elena Manuitt Brito, João Paulo Martins Miranda, Alex Batista Trentin, Robert F. H. Dekker and Mário Antônio Alves da Cunha
Fermentation 2024, 10(3), 143; https://doi.org/10.3390/fermentation10030143 - 1 Mar 2024
Cited by 4 | Viewed by 3338
Abstract
The industrial sector plays a significant role in global economic growth. However, it also produces polluting effluents that must be treated to prevent environmental damage and ensure the quality of life for future generations is not compromised. Various physical, chemical, and biological methods [...] Read more.
The industrial sector plays a significant role in global economic growth. However, it also produces polluting effluents that must be treated to prevent environmental damage and ensure the quality of life for future generations is not compromised. Various physical, chemical, and biological methods have been employed to treat industrial effluents. Filamentous fungi, in particular, have garnered attention as effective bioremediation agents due to their ability to produce enzymes capable of degrading recalcitrant compounds, and adsorb different pollutant molecules. The novelty of the work reported herein lies in its comprehensive assessment of the research surrounding the use of white- and brown-rot fungi for removing phenolic compounds from industrial effluents. This study employs a systematic review coupled with scientometric analysis to provide insights into the evolution of this technology over time. It scrutinizes geographical distribution, identifies research gaps and trends, and highlights the most studied fungal species and their applications. A systematic review of 464 publications from 1945 to 2023 assessed the use of these fungi in removing phenolic compounds from industrial effluents. White-rot fungi were predominant (96.3%), notably Phanerochaete chrysosporium, Pleurotus ostreatus, Trametes versicolor, and Lentinula edodes. The cultures employing free cells (64.15%) stand out over those using immobilized cells, just like cultures with isolated fungi regarding systems with microbial consortia. Geographically, Italy, Spain, Greece, India, and Brazil emerged as the most prominent countries in publications related to this area during the evaluated period. Full article
(This article belongs to the Special Issue Feature Review Papers in Industrial Fermentation 2023)
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25 pages, 2074 KiB  
Review
Fermentation Techniques and Biotechnological Applications of Modified Bacterial Cellulose: An Up-to-Date Overview
by Islam Sayah, Claudio Gervasi, Sami Achour and Teresa Gervasi
Fermentation 2024, 10(2), 100; https://doi.org/10.3390/fermentation10020100 - 8 Feb 2024
Cited by 1 | Viewed by 3168
Abstract
Bacterial cellulose (BC) is a pure exocellular polysaccharide produced by micro-organisms. It has several properties in comparison with plant-derived cellulose that make it perfectly suitable for many applications, ranging from the food industry to the biomedical area. Different production methods and modification or [...] Read more.
Bacterial cellulose (BC) is a pure exocellular polysaccharide produced by micro-organisms. It has several properties in comparison with plant-derived cellulose that make it perfectly suitable for many applications, ranging from the food industry to the biomedical area. Different production methods and modification or functionalization procedures have been investigated in response to the many possible attractive applications of BC. This review overviews the different fermentation techniques and functionalization methods together with the main possible biotechnological applications of BC for food industry and biomedical purposes. Full article
(This article belongs to the Special Issue Feature Review Papers in Industrial Fermentation 2023)
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18 pages, 386 KiB  
Review
Agro-Industrial Residues Used as Substrates for the Production of Bioaroma Compounds with Basidiomycetes: A Comprehensive Review
by Rafael Donizete Dutra Sandes, Raquel Anne Ribeiro dos Santos, Mônica Silva de Jesus, Hannah Caroline Santos Araujo, Maria Terezinha Santos Leite Neta, Gomathi Rajkumar and Narendra Narain
Fermentation 2024, 10(1), 23; https://doi.org/10.3390/fermentation10010023 - 28 Dec 2023
Cited by 1 | Viewed by 1751
Abstract
Flavoring compounds are substances that directly influence the acceptance or rejection of a product. They are considered as essential components in the industrial sector due to their wide range of applications in different areas, such as food, cosmetics and pharmaceuticals. With the growing [...] Read more.
Flavoring compounds are substances that directly influence the acceptance or rejection of a product. They are considered as essential components in the industrial sector due to their wide range of applications in different areas, such as food, cosmetics and pharmaceuticals. With the growing demand and concern of consumers for the acquisition of flavors from natural products, alternatives for the sustainable and low-cost production of such compounds becomes mandatory. Among these alternatives, biotechnological processes involving fungi are considered ecologically suitable and sustainable, as they tend to use conditions that are less harmful to the environment. The application of filamentous fungi such as basidiomycetes in biotechnological processes has been very promising, although it depends on the strain and growing conditions for obtaining bioaromas. The present review aims to compile reports on the potential of several basidiomycete fungi in the production of bioaromas using biotechnological methods. This review also includes the availability of nutrients and covers the new perspectives created with the application of agro-industrial residues as alternative cultivation substrates for these microorganisms. Thus, this is expected to consequently alleviate environmental pollution problems and enable the production of promising volatile compounds in a natural and sustainable way. Full article
(This article belongs to the Special Issue Feature Review Papers in Industrial Fermentation 2023)
30 pages, 5646 KiB  
Review
Fructooligosaccharides (FOS) Production by Microorganisms with Fructosyltransferase Activity
by Yadira Belmonte-Izquierdo, Luis Francisco Salomé-Abarca, Juan Carlos González-Hernández and Mercedes G. López
Fermentation 2023, 9(11), 968; https://doi.org/10.3390/fermentation9110968 - 12 Nov 2023
Cited by 3 | Viewed by 5360
Abstract
Fructans are fructose-based polymers, defined as fructooligosaccharides (FOS), when they possess a short chain. These molecules are highly appreciated in the food and pharmaceutical international market and have an increasing demand worldwide, mainly for their prebiotic activity and, therefore, for all their health [...] Read more.
Fructans are fructose-based polymers, defined as fructooligosaccharides (FOS), when they possess a short chain. These molecules are highly appreciated in the food and pharmaceutical international market and have an increasing demand worldwide, mainly for their prebiotic activity and, therefore, for all their health benefits to those who consume them constantly. Thus, new natural or alternative FOS production systems of industrial scale are needed. In this regard, microorganisms (prokaryotes and eukaryotes) have the potential to produce them through a wide and diverse number of enzymes with fructosyltransferase activity, which add a fructosyl group to sucrose or FOS molecules to elongate their chain. Microbial fructosyltransferases are preferred in the industry because of their high FOS production yields. Some of these enzymes include levansucrases, inulosucrases, and β-fructofuranosidases obtained and used through biotechnological tools to enhance their fructosyltransferase activity. In addition, characterizing new microorganisms with fructosyltransferase activity and modifying them could help to increase the production of FOS with a specific degree of polymerization and reduce the FOS production time, thus easing FOS obtention. Therefore, the aim of this review is to compile, discuss, and propose new perspectives about the microbial potential for FOS production through enzymes with fructosyltransferase activity and describe the modulation of FOS production yields by exogenous stimuli and endogenous modifications. Full article
(This article belongs to the Special Issue Feature Review Papers in Industrial Fermentation 2023)
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22 pages, 3021 KiB  
Review
Technological Insights on Glycerol Valorization into Propanediol through Thermocatalytic and Synthetic Biology Approaches
by Arash Yahyazadeh, Austin Bot, Sonil Nanda and Ajay K. Dalai
Fermentation 2023, 9(10), 894; https://doi.org/10.3390/fermentation9100894 - 6 Oct 2023
Cited by 2 | Viewed by 2417
Abstract
The adverse effects of climate change, predominantly propelled by greenhouse gas emissions from fossil fuels, underscore the urgency of seeking sustainable alternatives to fossil fuel use. Amid growing concerns about climate change caused by fossil fuels and petrochemicals, this review focuses on sustainable [...] Read more.
The adverse effects of climate change, predominantly propelled by greenhouse gas emissions from fossil fuels, underscore the urgency of seeking sustainable alternatives to fossil fuel use. Amid growing concerns about climate change caused by fossil fuels and petrochemicals, this review focuses on sustainable solutions through the conversion of glycerol into value-added biochemicals. Glycerol, as the main byproduct of biodiesel production, is a particularly attractive chemical due to its potential to be upgraded into value-added building blocks and biochemicals. This review provides a detailed analysis of different thermochemical (catalytic) and synthetic biology (fermentative) pathways for the conversion of glycerol into 1,2-propanediol and 1,3-propanediol, which have proven industrial and commercial applications globally. The synthesis of propanediol from glycerol hydrogenolysis and other catalytic processes using different active metals and acidic oxides is reviewed. The reaction mechanism involved in hydrogenolysis reactions concerning the surface reaction mechanism is systematically discussed. The metabolic activities of promising microorganisms in fermenting glycerol, as the carbon source used to produce propanediol, are illustrated and elaborated. Combining these insights, this review is a comprehensive resource that can foster a better understanding of glycerol transformation into propanediol and its implications for sustainable chemistry and industrial practices. This exploration of alternative methods emphasizes the potential of sustainable approaches to reshape production practices and contribute to climate change mitigation. Full article
(This article belongs to the Special Issue Feature Review Papers in Industrial Fermentation 2023)
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16 pages, 3067 KiB  
Review
Green Manufacturing of Steroids via Mycolicbacteria: Current Status and Development Trends
by Ming Zhao, Xiangfei Li, Liangbin Xiong, Kun Liu, Yan Liu, Zhenglian Xue and Rumeng Han
Fermentation 2023, 9(10), 890; https://doi.org/10.3390/fermentation9100890 - 3 Oct 2023
Cited by 1 | Viewed by 2702
Abstract
Steroids, the second largest drug category ranked after antibiotics, find widespread use in treatments for reproductive health, endocrine regulation, and inflammation. Advances in steroidal chemistry to date have led to the widespread use of sterols as starting substances in the development of environmentally [...] Read more.
Steroids, the second largest drug category ranked after antibiotics, find widespread use in treatments for reproductive health, endocrine regulation, and inflammation. Advances in steroidal chemistry to date have led to the widespread use of sterols as starting substances in the development of environmentally friendly biotechnologies for steroid production, including biocatalysis, microbial transformations, and biosynthesis using engineered micro-organisms. In this review, we synthesize some of the recent advancements in steroid biocatalysis using the Mycolicibacterium species, including the identification and modification of crucial elements for enhanced production. We also delve into the detailed characterization and reconstruction of metabolic pathways in specific microbial strains, shedding light on their potential for steroid biosynthesis. Additionally, we highlight the development of innovative de novo biosynthesis pathways for steroids within engineered cell factories. These results collectively provide an overview of the current landscape and emerging trends in green steroid manufacturing within the steroidal pharmaceutical industry. Full article
(This article belongs to the Special Issue Feature Review Papers in Industrial Fermentation 2023)
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